Search Results - "drug development"

"Endophytes: an unexplored treasure to combat Multidrug resistance" by Purvashi Pasrija, Meetali Girdhar, Mukesh Kumar, Shivani Arora, Anju Katyal

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A PDE10A inhibitor CPL500036 is a novel agent modulating striatal function devoid of most neuroleptic side-effects by Mikolaj Matloka, Sylwia Janowska, Piotr Pankiewicz, Sofiya Kokhanovska, Tomasz Kos, Małgorzata Hołuj, Izabela Rutkowska-Wlodarczyk, Krzysztof Abramski, Monika Janicka, Piotr Jakubowski, Maciej Świątkiewicz, Marlena Welniak-Kaminska, Joanna Hucz-Kalitowska, Paulina Dera, Lukasz Bojarski, Paweł Grieb, Piotr Popik, Maciej Wieczorek, Jerzy Pieczykolan

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Drug-like molecules with anti-trypanothione synthetase activity identified by high throughput screening by Diego Benítez, Jaime Franco, Florencia Sardi, Alejandro Leyva, Rosario Durán, Gahee Choi, Gyongseon Yang, Taehee Kim, Namyoul Kim, Jinyeong Heo, Kideok Kim, Honggun Lee, Inhee Choi, Constantin Radu, David Shum, Joo Hwan No, Marcelo A. Comini

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Inhibition of Chloride Intracellular Channel 1 (CLIC1) as Biguanide Class-Effect to Impair Human Glioblastoma Stem Cell Viability by Federica Barbieri, Roberto Würth, Alessandra Pattarozzi, Ivan Verduci, Chiara Mazzola, Maria G. Cattaneo, Michele Tonelli, Agnese Solari, Adriana Bajetto, Antonio Daga, Lucia M. Vicentini, Michele Mazzanti, Tullio Florio, Tullio Florio

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Efficacy, safety and mechanism of Simiaoyongan decoction in the treatment of carotid atherosclerotic plaque: a randomized, double-blind, placebo-controlled clinical trial protocol by QinHua Fan, ZhongJian Tan, WenQuan Su, QingXiao Li, Dian Jin, YaWei Du, LiPing Zhang, ShengXian Wu

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Screening a mushroom extract library for activity against <it>Acinetobacter baumannii </it>and <it>Burkholderia cepacia </it>and the identification of a compound with anti-<it>Burk... by Rott Marc, Toce Joseph, Monte Aaron, Klett Tiffany, Engelbrecht Kathleen, Gebhardt Michael, Dunek Craig, Schwan William R, Volk Thomas J, LiPuma John J, Liu Xue-Ting, McKelvey Ronald

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Circ_001653 alleviates sepsis associated-acute kidney injury by recruiting BUD13 to regulate KEAP1/NRF2/HO-1 signaling pathway by Xinxin Li, Wei Zhou, Jianjun Chen, Liangliang Zhou, Yingbing Li, Xufeng Wu, Xia Peng

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Maximising value from a United Kingdom Biomedical Research Centre: study protocol by Trisha Greenhalgh, Pavel V. Ovseiko, Nick Fahy, Sara Shaw, Polly Kerr, Alexander D. Rushforth, Keith M. Channon, Vasiliki Kiparoglou, On behalf of the Partnerships for Health, Wealth and Innovation cross-cutting theme of the National Institute for Health Research Biomedical Research Centre, Oxford

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Upregulation of casein kinase 1ε in dorsal root ganglia and spinal cord after mouse spinal nerve injury contributes to neuropathic pain by Zong Shuqin, Saegusa Hironao, Kouchi Kasumi, Kurihara Takashi, Sakurai Eri, Tanabe Tsutomu

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Perspectives on a Way Forward to Implementation of Precision Medicine in Patients With Diabetic Kidney Disease; Results of a Stakeholder Consensus-Building Meeting by Elisabeth Bakker, Peter G. M. Mol, Peter G. M. Mol, Peter G. M. Mol, João Nabais, João Nabais, Thorsten Vetter, Matthias Kretzler, John J. Nolan, Gert Mayer, Anna K. Sundgren, Hiddo J. L. Heerspink, Anja Schiel, Anja Schiel, Sieta T. de Vries, Maria F. Gomez, Friedrich Schulze, Dick de Zeeuw, Michelle J. Pena, for the BEAt-DKD Consortium

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Anti-proliferative and apoptosis-inducing effect of theabrownin against non-small cell lung adenocarcinoma A549 cells by Feifei Wu, Li Zhou, Wangdong Jin, Weiji Yang, Ying Wang, Bo Yan, Wenlin Du, Qiang Zhang, Lei Zhang, Yonghua Guo, Jin Zhang, Letian Shan, Thomas Efferth

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Clinical Utility of Osilodrostat in Cushing&rsquo;s Disease: Review of Currently Available Literature by Perosevic M, Tritos NA

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Molecular Psychiatry

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Protective effects of five compounds from Livistona chinensis R. Brown leaves against hypoxia/reoxygenation, H2O2, or adriamycin-induced injury in H9c2 cells by Li S, Luo S, Chen H, Zheng Y, Lin L, Yao H, Lin X

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Automated GMP-Compliant Production of [⁶⁸Ga]Ga-DO3A-Tuna-2 for PET Microdosing Studies of the Glucagon Receptor in Humans by Michael Wagner, Johan G. Doverfjord, Joachim Tillner, Gunnar Antoni, Torsten Haack, Martin Bossart, Iina Laitinen, Lars Johansson, Stefan Pierrou, Olof Eriksson, Irina Velikyan

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The Effects of Primary Unconjugated Bile Acids on Nanoencapsulated Pharmaceutical Formulation of Hydrophilic Drugs: Pharmacological Implications by Mooranian A, Foster T, Ionescu CM, Carey L, Walker D, Jones M, Wagle SR, Kovacevic B, Chester J, Johnstone E, Kuthubutheen J, Brown D, Atlas MD, Mikov M, Al-Salami H

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Antidiabetic and gastric emptying inhibitory effect of herbal Melia azedarach leaf extract in rodent models of diabetes type 2 mellitus by Seifu D, Gustafsson LE, Chawla R, Genet S, Debella A, Holst M, Hellström PM

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MUC1 and CREB3 are Hub Ferroptosis Suppressors for Nucleus Pulposus and Annulus Fibrosus Degeneration by Integrated Bioinformatics and Experimental Verification by Yang X, Li Q, Wang L, Chen J, Quan Z

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Prediction of Targets of Curculigoside A in Osteoporosis and Rheumatoid Arthritis Using Network Pharmacology and Experimental Verification by Han J, Wan M, Ma Z, Hu C, Yi H

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Investigation of Wound Healing and Anti-Inflammatory Activities of Leaf Gel of Aloe trigonantha L.C. Leach in Rats by Tazeze H, Mequanente S, Nigussie D, Legesse B, Makonnen E, Mengie T

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