Search Results - "drug development"

Use of patient-reported outcomes (PRO) data to complement exposure-response analysis in early clinical cancer drug development by Huiming Xia, Brian P. Booth, Yaning Wang, Chunling Fan, Vishal Bhatnagar, Paul Kluetz, Jeanne Fourie Zirkelbach

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Study Design Selection in Early Clinical Anti‐Hyperglycemic Drug Development: A Simulation Study of Glucose Tolerance Tests by Moustafa M. A. Ibrahim, Siti M. S. Ghadzi, Maria C. Kjellsson, Mats O. Karlsson

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Advances in quantitative methods and modeling for complex generic drugs and opportunities to hybridize learnings between innovator and generic drug developers by Priya Jayachandran

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Artificial intelligence-enabled social media listening to inform early patient-focused drug development: perspectives on approaches and strategies by Erica Spies, Jennifer A. Flynn, Nuno Guitian Oliveira, Prathamesh Karmalkar, Harsha Gurulingappa

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An Innovative Disease‐Drug‐Trial Framework to Guide Binge Eating Disorder Drug Development: A Case Study for Topiramate by Shamir N. Kalaria, Susan L. McElroy, Jogarao Gobburu, Mathangi Gopalakrishnan

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Targeting FMN, TPP, SAM-I, and glmS Riboswitches with Chimeric Antisense Oligonucleotides for Completely Rational Antibacterial Drug Development by Nikolet Pavlova, Martina Traykovska, Robert Penchovsky

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Analysis of Biologics Molecular Descriptors towards Predictive Modelling for Protein Drug Development Using Time-Gated Raman Spectroscopy by Jaakko Itkonen, Leo Ghemtio, Daniela Pellegrino, Pia J. Jokela (née Heinonen), Henri Xhaard, Marco G. Casteleijn

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Cystic Fibrosis Treatment: A Paradigm for New Pediatric Medicines, Globalization of Drug Development and the Role of the European Medicines Agency by Klaus Rose, Michael G. Spigarelli

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EMA perspective on the value of model‐informed drug development for labeling recommendations regarding medicine use during pregnancy and breastfeeding by Efthymios Manolis, Flora Tshinanu Musuamba, Corinne S. deVries, Pieter J. Colin, Martin B. Oleksiewicz

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Impacts of FDA approval and Medicare restriction on antiamyloid therapies for Alzheimer's disease: patient outcomes, healthcare costs, and drug development by Rouen Brockmann, Joanna Nixon, Bryan L. Love, Ismaeel Yunusa

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Improving Pediatric Drug Development: Challenges, Opportunities and Lessons LearnedBook review prepared for Frontiers in Pediatric Clinical Pharmacology by Donald eMattison

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Multi-Compartment 3D-Cultured Organ-on-a-Chip: Towards a Biomimetic Lymph Node for Drug Development by Aya Shanti, Bisan Samara, Amal Abdullah, Nicholas Hallfors, Dino Accoto, Jiranuwat Sapudom, Aseel Alatoom, Jeremy Teo, Serena Danti, Cesare Stefanini

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Marine Sponge Xestospongia sp.: A Promising Source for Tuberculosis Drug Development - Computational Insights into Mycobactin Biosynthesis Inhibition by Arfan Arfan, Aiyi Asnawi, La Ode Aman

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Commercially Available Cell-Free Permeability Tests for Industrial Drug Development: Increased Sustainability through Reduction of In Vivo Studies by Ann-Christin Jacobsen, Sonja Visentin, Cosmin Butnarasu, Paul C. Stein, Massimiliano Pio di Cagno

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Molecular Mechanisms and Drug Development in Aquaporin Water Channel Diseases: Molecular Mechanism of Water Channel Aquaporin-2 Trafficking by Yumi Noda, Sei Sasaki

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Navigating a transforming landscape: the evolving role of pharmacovigilance physicians in drug development and implications for future challenges and training requirements by Tarek A. Hammad, Salman Afsar, Herve Le-Louet, Herve Le-Louet, Veronique F. Kugener

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Review on the potential of 1,3,4-Oxadiazine derivatives: Synthesis, structure-activity relationship, and future prospects in drug development by Saleem Akbar, Subham Das, Rikeshwer Prasad Dewangan, Alex Joseph, Bahar Ahmed

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A Model-Informed Drug Development (MIDD) Approach for a Low Dose of Empagliflozin in Patients with Type 1 Diabetes by Curtis K. Johnston, Rena J. Eudy-Byrne, Ahmed Elmokadem, Valerie Nock, Jan Marquard, Nima Soleymanlou, Matthew M. Riggs, Karl-Heinz Liesenfeld

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Integrating risk minimization planning throughout the clinical development and commercialization lifecycle: an opinion on how drug development could be improved by Morrato EH, Smith MY

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Supervised Relation Extraction Between Suicide-Related Entities and Drugs: Development and Usability Study of an Annotated PubMed Corpus by Karina Karapetian, Soo Min Jeon, Jin-Won Kwon, Young-Kyoon Suh

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