Search Results - "drug development"

Analysis of Global Drug Development Pathways and Postmarketing Safety in Japan: Local Studies May Reduce Drug‐Related Deaths by Tomoko Kawamura Okubo, Shunsuke Ono

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Novel Targets and Biomarkers in Solid Tumors

Subjects: “…drug development…”
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Novel Targets and Biomarkers in Solid Tumors, 2nd Edition

Subjects: “…drug development…”
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Nuclear Receptors as Targets for Drug Development: Peroxisome Proliferator-Activated Receptor γ in Mast Cells: Its Roles in Proliferation and Differentiation by Kazutaka Maeyama, Maiko Emi, Masashi Tachibana

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Type 2 Diabetes Complicated With Heart Failure: Research on Therapeutic Mechanism and Potential Drug Development Based on Insulin Signaling Pathway by Hui Ye, Yanan He, Chuan Zheng, Fang Wang, Ming Yang, Junzhi Lin, Runchun Xu, Dingkun Zhang

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Novel Situations of Endothelial Injury in Stroke - Mechanisms of Stroke and Strategy of Drug Development: Protective Effects of Antiplatelet Agents Against Stroke by Masamitsu Shimazawa, Hideaki Hara

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Model‐informed drug development of voxelotor in sickle cell disease: Exposure‐response analysis to support dosing and confirm mechanism of action by Michelle L. Green, Radojka M. Savic, Margaret Tonda, Karin Jorga, Carla B. Washington

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Precision Nanotoxicology in Drug Development: Current Trends and Challenges in Safety and Toxicity Implications of Customized Multifunctional Nanocarriers for Drug-Delivery Applications by Anas Ahmad, Mohammad Imran, Nisha Sharma

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Molecular Mechanisms and Drug Development in Aquaporin Water Channel Diseases: Water Channel Aquaporin-2 of Kidney Collecting Duct Cells by Kuniaki Takata, Yuki Tajika, Toshiyuki Matsuzaki, Takeo Aoki, Takeshi Suzuki, Ablimit Abduxukur, Haruo Hagiwara

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How Compounding Pharmacies Fill Critical Gaps in Pediatric Drug Development Processes: Suggested Regulatory Changes to Meet Future Challenges by Robert B. MacArthur, Lisa D. Ashworth, Keming Zhan, Richard H. Parrish

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Challenges and Opportunities for Companies to Build HTA/Payer Perspectives Into Drug Development Through the Use of a Dynamic Target Product Profile by Ting Wang, Ting Wang, Neil McAuslane, Wim G. Goettsch, Wim G. Goettsch, Hubert G. M. Leufkens, Marie L. De Bruin

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Differentiated HASTR/ci35 cells: A promising in vitro human astrocyte model for facilitating CNS drug development studies by Keita Kitamura, Ryo Ito, Kenta Umehara, Hanae Morio, Kosuke Saito, Shota Suzuki, Mari Hashimoto, Yoshiro Saito, Naohiko Anzai, Hidetaka Akita, Kan Chiba, Tomomi Furihata

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Consideration of a Credibility Assessment Framework in Model‐Informed Drug Development: Potential Application to Physiologically‐Based Pharmacokinetic Modeling and Simulation by Colleen Kuemmel, Yuching Yang, Xinyuan Zhang, Jeffry Florian, Hao Zhu, Million Tegenge, Shiew‐Mei Huang, Yaning Wang, Tina Morrison, Issam Zineh

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Molecular Mechanisms and Drug Development in Aquaporin Water Channel Diseases: Aquaporin Superfamily (Superaquaporins): Expansion of Aquaporins Restricted to Multicellular Organisms by Yoshiyuki Morishita, Yasuji Sakube, Sei Sasaki, Kenichi Ishibashi

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Functional Proteins Involved in Regulation of Intracellular Ca2+ for Drug Development: Desensitization of N-Methyl-D-aspartate Receptor Channels by Noritaka Nakamichi, Yukio Yoneda

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Expanding the use of real‐world data through the development of user‐friendly tools to support drug development: Example of an organ impairment dashboard by Bianca Vora, Erick Velasquez, Rong Zhang, Krystian Igras, Spencer L. James, Pascal Chanu

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How Molecular Topology Can Help in Amyotrophic Lateral Sclerosis (ALS) Drug Development: A Revolutionary Paradigm for a Merciless Disease by Maria Galvez-Llompart, Riccardo Zanni, Ramon Garcia-Domenech, Jorge Galvez

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Rituximab pediatric drug development: Pharmacokinetic and pharmacodynamic modeling to inform regulatory approval for rituximab treatment in patients with granulomatosis with polyangiitis or microscopic polyangiitis by Candice Jamois, Leonid Gibiansky, Clarisse Chavanne, Melissa Cheu, Patricia B. Lehane, Pooneh Pordeli, Simone Melega, Jacques Gaudreault

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The importance of pharmacokinetics and pharmacodynamics in antimicrobial drug development and their influence on the success of agents developed to combat resistant gram negative pathogens: A review by Mary E. Palmer, Lauren J. Andrews, Taylor C. Abbey, Ashley E. Dahlquist, Eric Wenzler

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Integration of In Silico, In Vitro and In Situ Tools for the Preformulation and Characterization of a Novel Cardio-Neuroprotective Compound during the Early Stages of Drug Development by Claudia Miranda, Alejandro Ruiz-Picazo, Paula Pomares, Isabel Gonzalez-Alvarez, Marival Bermejo, Marta Gonzalez-Alvarez, Alex Avdeef, Miguel-Ángel C

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