Search Results - "drug development"

Bilirubin Improves Gap Junction to Alleviate Doxorubicin-Induced Cardiotoxicity by Regulating AMPK-Axl-SOCS3-Cx43 Axis by Siqi Zhang, Yixin Fan, Yixin Fan, Binbin Zheng, Yu Wang, Chen Miao, Yue Su, Kun Li, Yan E., Xueli Wang, Xueming He, Xuefeng Wu, Chenjie Xu, Yulin Tang, Wen-Tao Liu, Wen-Tao Liu, Xiangqing Kong, Liang Hu

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Developing new drugs from annals of Chinese medicine by Zhaoxiang Bian, Shilin Chen, Chungwah Cheng, Jun Wang, Haitao Xiao, Hongyan Qin

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Role of Hepatocyte Transporters in Drug-Induced Liver Injury (DILI)-In Vitro Testing by Péter Tátrai, Franciska Erdő, Péter Krajcsi

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Comprehensive Physiologically Based Pharmacokinetic Model to Assess Drug-Drug Interactions of Phenytoin by Leyanis Rodriguez-Vera, Xuefen Yin, Mohammed Almoslem, Karolin Romahn, Brian Cicali, Viera Lukacova, Rodrigo Cristofoletti, Stephan Schmidt

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Regulation of Schistosoma mansoni development and reproduction by the mitogen-activated protein kinase signaling pathway. by Luiza Freire de Andrade, Marina de Moraes Mourão, Juliana Assis Geraldo, Fernanda Sales Coelho, Larissa Lopes Silva, Renata Heisler Neves, Angela Volpini, José Roberto Machado-Silva, Neusa Araujo, Rafael Nacif-Pimenta, Conor R Caffrey, Guilherme Oliveira

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Identification of covalent active site inhibitors of dengue virus protease by Koh-Stenta X, Joy J, Wang SF, Kwek PZ, Wee JLK, Wan KF, Gayen S, Chen AS, Kang C, Lee MA, Poulsen A, Vasudevan SG, Hill J, Nacro K

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Discovery of novel anti-tumor compounds targeting PARP-1 with induction of autophagy through in silico and in vitro screening by Danfeng Shi, Qianqian Pang, Qianyu Qin, Xinsheng Yao, Xiaojun Yao, Yang Yu

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High-Altitude Medicinal Plants as Promising Source of Phytochemical Antioxidants to Combat Lifestyle-Associated Oxidative Stress-Induced Disorders by Mohammad Vikas Ashraf, Sajid Khan, Surya Misri, Kailash S. Gaira, Sandeep Rawat, Balwant Rawat, M. A. Hannan Khan, Ali Asghar Shah, Mohd Asgher, Shoeb Ahmad

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Structure-based drug discovery of novel fused-pyrazolone carboxamide derivatives as potent and selective AXL inhibitors by Feifei Fang, Yang Dai, Hao Wang, Yinchun Ji, Xuewu Liang, Xia Peng, Jiyuan Li, Yangrong Zhao, Chunpu Li, Danyi Wang, Yazhou Li, Dong Zhang, Dan Zhang, Meiyu Geng, Hong Liu, Jing Ai, Yu Zhou

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The Coming of Age of AI/ML in Drug Discovery, Development, Clinical Testing, and Manufacturing: The FDA Perspectives by Niazi SK

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A Review on the Pharmacological Aspects of Engeletin as Natural Compound by Zhong X, Huang R, Chen X, Lei Y

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Quantitative Structure - Pharmacokinetic Relationships for Plasma Clearance of Basic Drugs with Consideration of the Major Elimination Pathway by Zvetanka Dobreva Zhivkova

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Retrospective Assessment of Translational Pharmacokinetic-Pharmacodynamic Modeling Performance: A Case Study with Apitolisib, a Dual PI3K/mTOR Inhibitor by Anita Moein, Jin Y. Jin, Matthew R. Wright, Bruno Alicke, Harvey Wong

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Artificial Intelligence and Machine Learning Models for Predicting Drug-Induced Kidney Injury in Small Molecules by Mohan Rao, Vahid Nassiri, Sanjay Srivastava, Amy Yang, Satjit Brar, Eric McDuffie, Clifford Sachs

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Drug repositioning: A bibliometric analysis by Guojun Sun, Dashun Dong, Zuojun Dong, Qian Zhang, Hui Fang, Chaojun Wang, Shaoya Zhang, Shuaijun Wu, Yichen Dong, Yuehua Wan

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HAZ, a novel peptide with broad-spectrum antibacterial activity by Mohammad Alsaggar, Mohammad Al-Hazabreh, Yara Al Tall, Alaa Al-Tarawneh, Ruba S. Darweesh, Majed Masadeh

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Chagas Disease Treatment and Rational Drug Discovery: A Challenge That Remains by Ana Catarina Cristovão Silva, Ana Catarina Cristovão Silva, Maria Carolina Accioly Brelaz-, Maria Carolina Accioly Brelaz-, Ana Cristina Lima Leite, Valéria Rêgo Alves Pereira, Marcelo Zaldini Hernandes

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Vascular Endothelial Growth Factor (VEGF) and VEGF Receptor Inhibitors in Health and Disease by Sylvain Broussy

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Editorial: Medicinal plants as a source of novel autoimmune-modulating and anti-inflammatory drug products by Yang Wang, Yang Wang, Ji Chen, Jun Tian, Yihai Wang, Zhengang Zha, Xiaobin Zeng, Xiaobin Zeng

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Characterizing the reproducibility in using a liver microphysiological system for assaying drug toxicity, metabolism, and accumulation by Andrés Rubiano, Amruta Indapurkar, Ryosuke Yokosawa, Alina Miedzik, Barry Rosenzweig, Ayesha Arefin, Chloe M. Moulin, Keri Dame, Neil Hartman, Donna A. Volpe, Murali K. Matta, David J. Hughes, David G. Strauss, Tomasz Kostrzewski, Alexandre J. S. Ribeiro

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