Search Results - "hydroxyl"

Metabolic stability and metabolite profiling of emerging synthetic cathinones by Rita P. Lopes, Rita P. Lopes, Raquel A. Ferro, Raquel A. Ferro, Margarida Milhazes, Margarida Figueira, Maria João Caldeira, Alexandra M. M. Antunes, Helena Gaspar, Helena Gaspar

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Pharmacokinetics, metabolite profiling, safety and tolerability of YZJ-4729 tartrate, a novel G protein-biased μ-opioid receptor agonist, in healthy Chinese subjects by Yufeng Ni, Yufeng Ni, Huaye Gao, Huaye Gao, Wen Ouyang, Guoping Yang, Minlu Cheng, Minlu Cheng, Li Ding, Li Ding

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Multiparameter ranking of carbazoles for anti-trypanosome lead discovery by Amrita Sharma, Carlos E. Sanz-Rodriguez, Michael P. Pollastri, Andrei Purmal, Kojo Mensa-Wilmot, Kojo Mensa-Wilmot

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Bioanalytical LC-QTOF/MS Method for a <i>N</i>-phenylpiperazine Derivate (LQFM05): An Anxiolytic- and Antidepressant-like Prototype Drug Applied to Pharmacokinetic and Biodistribut... by Ana Cláudia M. Ramos, Kênnia R. Rezende, Carolina M. Teixeira, Aline R. Fernandes, Heloa Santos, Rúbia Darc Machado, Ricardo Menegatti, Boniek G. Vaz, Andréa R. Chaves

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Substrate Specificity of Human Cytochrome P450 (CYP) 2C Subfamily and Effect of Azole Antifungal Agents on CYP2C8 by Toshiro Niwa, Yurie Imagawa

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Biotransformation of Modified Benzylisoquinoline Alkaloids: Boldine and Berberine and In Silico Molecular Docking Studies of Metabolites on Telomerase and Human Protein Tyrosine Ph... by Duaa Eliwa, Abdel-Rahim S. Ibrahim, Amal Kabbash, Mona El-Aasr, Michał Tomczyk, Yousef A. Bin Jardan, Gaber El-Saber Batiha, Amany E. Ragab

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Cyp2c-deficiency depletes muricholic acids and protects against high-fat diet-induced obesity in male mice but promotes liver damage by Antwi-Boasiako Oteng, Sei Higuchi, Alexander S. Banks, Rebecca A. Haeusler

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Metabolism and toxicity of usnic acid and barbatic acid based on microsomes, S9 fraction, and 3T3 fibroblasts in vitro combined with a UPLC-Q-TOF-MS method by Hanxue Wang, Hanxue Wang, Hanxue Wang, Min Xuan, Juanjuan Diao, Nan Xu, Manlin Li, Cheng Huang, Changhong Wang

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Anti-Inflammatory Potential of Daturaolone from <i>Datura innoxia</i> Mill.: In Silico, In Vitro and In Vivo Studies by Muhammad Waleed Baig, Humaira Fatima, Nosheen Akhtar, Hidayat Hussain, Mohammad K. Okla, Abdulrahman Al-Hashimi, Wahidah H. Al-Qahtani, Hamada AbdElgawad, Ihsan-ul Haq

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Estrogen metabolite ratio: Is the 2-hydroxyestrone to 16&alpha;-hydroxyestrone ratio predictive for breast cancer? by Nadia Obi, Alina Vrieling, Judith Heinz

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Unveiling the Phytochemical Profile and Biological Potential of Five <i>Artemisia</i> Species by Adriana Trifan, Gokhan Zengin, Kouadio Ibrahime Sinan, Elwira Sieniawska, Rafal Sawicki, Magdalena Maciejewska-Turska, Krystyna Skalikca-Woźniak, Simon Vlad Luca

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A Comparative Study of Serum Pharmacochemistry of Kai-Xin-San in Normal and AD Rats Using UPLC-LTQ-Orbitrap-MS by Lin Yang, Jian Liang, Qin Zheng, Lifen Zhou, Yongchang Xiong, Huijuan Wang, Jinbin Yuan

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Simulation of Physicochemical and Pharmacokinetic Properties of Vitamin D₃ and Its Natural Derivatives by Subrata Deb, Anthony Allen Reeves, Suki Lafortune

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Characterization of CYP3A pharmacogenetic variation in American Indian and Alaska Native communities, targeting CYP3A4*1G allele function by Alison E. Fohner, Rachel Dalton, Kasse Skagen, Konner Jackson, Katrina G. Claw, Scarlett E. Hopkins, Renee Robinson, Burhan A. Khan, Bhagwat Prasad, Erin G. Schuetz, Deborah A. Nickerson, Timothy A. Thornton, Denise A. Dillard, Bert B. Boyer, Kenneth E. Thummel, Erica L. Woodahl

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560G>A (rs4986782) (R187Q) Single Nucleotide Polymorphism in Arylamine N-Acetyltransferase 1 Increases Affinity for the Aromatic Amine Carcinogens 4-Aminobiphenyl and N-Hydroxy-4-A... by Mark A. Doll, David W. Hein

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Bioaccumulation and biotransformation of simvastatin in probiotic bacteria: A step towards better understanding of drug-bile acids-microbiome interactions by Maja Đanić, Nebojša Pavlović, Slavica Lazarević, Bojan Stanimirov, Saša Vukmirović, Hani Al-Salami, Hani Al-Salami, Armin Mooranian, Armin Mooranian, Momir Mikov

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NF-κB mediated regulation of tumor cell proliferation in hypoxic microenvironment by Shubham Rastogi, Sara Aldosary, Abdulaziz S. Saeedan, Mohd. Nazam Ansari, Manjari Singh, Gaurav Kaithwas

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Essential fatty acids and lipid mediators. Endocannabinoids by G. Caramia

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Evaluation of the usefulness of plasma 4β‐hydroxycholesterol concentration normalized by 4α‐hydroxycholesterol for accurate CYP3A phenotyping by Ayako Oda, Yosuke Suzuki, Haruki Sato, Teruhide Koyama, Masahiro Nakatochi, Yukihide Momozawa, Ryota Tanaka, Hiroyuki Ono, Ryosuke Tatsuta, Tadasuke Ando, Toshitaka Shin, Kenji Wakai, Keitaro Matsuo, Hiroki Itoh, Keiko Ohno

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Identification of the Hepatic Metabolites of Flumazenil and their Kinetic Application in Neuroimaging by Wei-Hsi Chen, Chuang-Hsin Chiu, Shiou-Shiow Farn, Kai-Hung Cheng, Yuan-Ruei Huang, Shih-Ying Lee, Yao-Ching Fang, Yu-Hua Lin, Kang-Wei Chang

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