Resultados da pesquisa - "knockout mice"

Hepatic Monoacylglycerol O-acyltransferase 1 as a Promising Therapeutic Target for Steatosis, Obesity, and Type 2 Diabetes Por Yasuhiro Hayashi, Erina Suemitsu, Kazuaki Kajimoto, Yusuke Sato, Afsana Akhter, Yu Sakurai, Hiroto Hatakeyama, Mamoru Hyodo, Noritada Kaji, Yoshinobu Baba, Hideyoshi Harashima

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Transient Receptor Potential Vanilloid 1 - a Polymodal Nociceptive Receptor - Plays a Crucial Role in Formaldehyde-Induced Skin Inflammation in Mice Por Haruki Usuda, Takumi Endo, Ayumi Shimouchi, Asaka Saito, Makoto Tominaga, Hirotaka Yamashita, Hiroichi Nagai, Naoki Inagaki, Hiroyuki Tanaka

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Adipose Tissue SIRT1 Regulates Insulin Sensitizing and Anti-Inflammatory Effects of Berberine Por Yun Shan, Yun Shan, Shuchen Zhang, Shuchen Zhang, Bin Gao, Bin Gao, Shu Liang, Hao Zhang, Xizhong Yu, Juan Zhao, Lifang Ye, Lifang Ye, Qin Yang, Wenbin Shang, Wenbin Shang

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Sestrin1, 2, and 3 are dispensable for female fertility in mice Por Mengchen Wang, Wenhui Chen, Xinxin Zeng, Taojun Wang, Yingpu Sun, Qingling Yang

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Stimulation of Hepatic Ferritinophagy Mitigates <i>Irp2</i> Depletion-Induced Anemia Por Yutong Liu, Yuxuan Li, Liu Yang, Jiaqi Shen, Hongting Zhao, Weichen Dong, Yanzhong Chang, Tong Qiao, Kuanyu Li

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NOX1/NADPH oxidase is involved in the LPS-induced exacerbation of collagen-induced arthritis Por Misaki Matsumoto, Junjie Liu, Kazumi Iwata, Masakazu Ibi, Nozomi Asaoka, Xueqing Zhang, Masato Katsuyama, Masaya Matsuda, Takeshi Nabe, Katrin Schröder, Chihiro Yabe-Nishimura

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Heat‐killed Lactobacillus murinus confers neuroprotection against dopamine neuronal loss by targeting NLRP3 inflammasome Por Hong‐Xia Fan, Shuo Sheng, Dai‐Di Li, Jing‐Jie Li, Guo‐Qing Wang, Feng Zhang

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High infectivity and unique genomic sequence characteristics of Cryptosporidium parvum in China. Por Ruilian Jia, Wanyi Huang, Ni Huang, Zhengjie Yu, Na Li, Lihua Xiao, Yaoyu Feng, Yaqiong Guo

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Loss of the Kidney Urate Transporter, Urat1, Leads to Disrupted Redox Homeostasis in Mice Por Neema Jamshidi, Kabir B. Nigam, Sanjay K. Nigam

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The Role of Voltage-Gated Sodium Channel 1.8 in the Effect of Atropine on Heart Rate: Evidence From a Retrospective Clinical Study and Mouse Model Por Baowen Liu, Baowen Liu, Ningbo Li, Jin Zhang, Yi Liu, Mi Zhang, Yishun Hong, Wenyao Wu, Xianwei Zhang, Guangyou Duan

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Off-target effects of the lysosomal acid lipase inhibitors Lalistat-1 and Lalistat-2 on neutral lipid hydrolases Por Ivan Bradić, Katharina B. Kuentzel, Sophie Honeder, Gernot F. Grabner, Nemanja Vujić, Robert Zimmermann, Ruth Birner-Gruenberger, Dagmar Kratky

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Deletion of Glyoxalase 1 Exacerbates Acetaminophen-Induced Hepatotoxicity in Mice Por Prakashkumar Dobariya, Wei Xie, Swetha Pavani Rao, Jiashu Xie, Davis M. Seelig, Robert Vince, Michael K. Lee, Swati S. More

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Haploinsufficient TNAP Mice Display Decreased Extracellular ATP Levels and Expression of Pannexin-1 Channels Por Álvaro Sebastián-Serrano, Álvaro Sebastián-Serrano, Laura de Diego-García, Laura de Diego-García, David C. Henshall, David C. Henshall, Tobías Engel, Tobías Engel, Miguel Díaz-Hernández, Miguel Díaz-Hernández

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Molecular Mechanism of Macrophage Activation by Red Ginseng Acidic Polysaccharide from Korean Red Ginseng Por Se Eun Byeon, Jaehwi Lee, Ji Hye Kim, Woo Seok Yang, Yi-Seong Kwak, Sun Young Kim, Eui Su Choung, Man Hee Rhee, Jae Youl Cho

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MFG-E8 Knockout Aggravated Nonalcoholic Steatohepatitis by Promoting the Activation of TLR4/NF-κB Signaling in Mice Por Jun Hu, Hui Du, Yinglin Yuan, Peipei Guo, Junxia Yang, Xinru Yin, Jin Liu, Shengwang Wu, Jingyuan Wan, Xia Gong

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Vimentin-Rab7a Pathway Mediates the Migration of MSCs and Lead to Therapeutic Effects on ARDS Por Kai Wang, Boxiang Du, Yan Zhang, Congyou Wu, Xiuli Wang, Xu Zhang, Liwei Wang

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IFN-γ plays a unique role in protection against low virulent Trypanosoma cruzi strain. Por Adele A Rodrigues, Jasson S S Saosa, Grace K da Silva, Flávia A Martins, Aline A da Silva, Cecílio P da Silva Souza Neto, Catarina V Horta, Dario S Zamboni, João S da Silva, Eloisa A V Ferro, Claudio V da Silva

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NIL10: A New IL10-Receptor Binding Nanoparticle That Induces Cardiac Protection in Mice and Pigs Subjected to Acute Myocardial Infarction through STAT3/NF-κB Activation Por Laura Tesoro, Ignacio Hernández, Rafael Ramírez-Carracedo, Javier Díez-Mata, Nunzio Alcharani, Beatriz Jiménez-Guirado, Karina Ovejero-Paredes, Marco Filice, Jose Luis Zamorano, Marta Saura, Carlos Zaragoza, Laura Botana

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Selenoprotein K Increases Efficiency of DHHC6 Catalyzed Protein Palmitoylation by Stabilizing the Acyl-DHHC6 Intermediate Por Gregory J. Fredericks, FuKun W. Hoffmann, Robert J. Hondal, Sharon Rozovsky, Johann Urschitz, Peter R. Hoffmann

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Melatonin/Nrf2/NLRP3 Connection in Mouse Heart Mitochondria during Aging Por Marisol Fernández-Ortiz, Ramy K. A. Sayed, José Fernández-Martínez, Antonia Cionfrini, Paula Aranda-Martínez, Germaine Escames, Tomás de Haro, Darío Acuña-Castroviejo

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