Search Results - "knockout mouse"

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  1. 61
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    Combined genetic deletion of GDF15 and FGF21 has modest effects on body weight, hepatic steatosis and insulin resistance in high fat fed mice by Satish Patel, Afreen Haider, Anna Alvarez-Guaita, Guillaume Bidault, Julia Sarah El-Sayed Moustafa, Esther Guiu-Jurado, John A. Tadross, James Warner, James Harrison, Samuel Virtue, Fabio Scurria, Ilona Zvetkova, Matthias Blüher, Kerrin S. Small, Stephen O'Rahilly, David B. Savage

    Published 2022
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  2. 62
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    Prevention of Ulcerative Colitis by Autologous Metabolite Transfer from Colitogenic Microbiota Treated with Lipid Nanoparticles Encapsulating an Anti-Inflammatory Drug Candidate by Chunhua Yang, Junsik Sung, Dingpei Long, Zahra Alghoul, Didier Merlin

    Published 2022
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  3. 63
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    Klf6 protects β-cells against insulin resistance-induced dedifferentiation by Christopher Dumayne, David Tarussio, Ana Rodriguez Sanchez-Archidona, Alexandre Picard, Davide Basco, Xavier Pascal Berney, Mark Ibberson, Bernard Thorens

    Published 2020
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  4. 64
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    Osteoglycin, a novel coordinator of bone and glucose homeostasis by N.J. Lee, N. Ali, L. Zhang, Y. Qi, I. Clarke, R.F. Enriquez, M. Brzozowska, I.C. Lee, M.J. Rogers, D.R. Laybutt, J.R. Center, P.A. Baldock, H. Herzog

    Published 2018
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  5. 65
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    Progress toward therapeutic potential for AFQ056 in Fragile X syndrome by Sourial M, Cheng C, Doering LC

    Published 2013
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  6. 66
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    Disturbance of Response to Acute Thermal Pain in Naturally Occurring Cholecystokinin-A Receptor Gene Knockout Otsuka Long-Evans Tokushima Fatty (OLETF) Rats by Miyasaka Kyoko, Nomoto Shigeki, Ohta Minoru, Kanai Setsuko, Kaneko Takao, Tahara Shoichi, Funakoshi Akihiro

    Published 2006
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  7. 67
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    Obacunone Retards Renal Cyst Development in Autosomal Dominant Polycystic Kidney Disease by Activating NRF2 by Zhiwei Qiu, Jinzhao He, Guangying Shao, Jiaqi Hu, Xiaowei Li, Hong Zhou, Min Li, Baoxue Yang

    Published 2021
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  8. 68
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    Rb1 negatively regulates bone formation and remodeling through inhibiting transcriptional regulation of YAP in Glut1 and OPG expression and glucose metabolism in male mice by Yang Li, Shuting Yang, Shuying Yang

    Published 2022
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  9. 69
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    An Analysis of the Expression and Association with Immune Cell Infiltration of the cGAS/STING Pathway in Pan-Cancer by Xiang An, Yuanyuan Zhu, Tongsen Zheng, Guangyu Wang, Minghui Zhang, Jiade Li, Hongbo Ji, Shijun Li, Shucai Yang, Dandan Xu, Zhiwei Li, Tianzhen Wang, Yan He, Lei Zhang, Weiwei Yang, Ran Zhao, Dapeng Hao, Xiaobo Li

    Published 2019
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  10. 70
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    Pharmacological Interaction With the Sigma1 (σ1)-Receptor in the Acute Behavioral Effects of Antidepressants by Vanessa Villard, Johann Meunier, Nathalie Chevallier, Tangui Maurice

    Published 2011
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  11. 71
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    Soluble Epoxide Hydrolase Deletion Limits High-Fat Diet-Induced Inflammation by Karen M. Wagner, Jun Yang, Christophe Morisseau, Bruce D. Hammock

    Published 2021
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  12. 72
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    METTL3-mediated m6A mRNA modification promotes esophageal cancer initiation and progression via Notch signaling pathway by Hui Han, Chunlong Yang, Shuishen Zhang, Maosheng Cheng, Siyao Guo, Yan Zhu, Jieyi Ma, Yu Liang, Lu Wang, Siyi Zheng, Zhaoyu Wang, Demeng Chen, Yi-Zhou Jiang, Shuibin Lin

    Published 2021
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  13. 73
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    Apoc2 loss-of-function zebrafish mutant as a genetic model of hyperlipidemia by Chao Liu, Keith P. Gates, Longhou Fang, Marcelo J. Amar, Dina A. Schneider, Honglian Geng, Wei Huang, Jungsu Kim, Jennifer Pattison, Jian Zhang, Joseph L. Witztum, Alan T. Remaley, P. Duc Dong, Yury I. Miller

    Published 2015
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  14. 74
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    Pancreatic beta-cell specific BAG3 knockout results in chronic hyperinsulinemia inducing insulin resistance by Verena Damiani, Alessia Lamolinara, Ilaria Cicalini, Maria Concetta Cufaro, Francesco Del Pizzo, Federica Di Marco, Piero Del Boccio, Beatrice Dufrusine, Michael Hahne, Rossano Lattanzio, Damiana Pieragostino, Manuela Iezzi, Massimo Federici, Maria Caterina Turco, Arianna Maiorana, Carlo Dionisi-Vici, Vincenzo De Laurenzi

    Published 2023
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  15. 75
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    Genome-Wide Association Study-Guided Exome Rare Variant Burden Analysis Identifies IL1R1 and CD3E as Potential Autoimmunity Risk Genes for Celiac Disease by Haifa Mansour, Haifa Mansour, Babajan Banaganapalli, Babajan Banaganapalli, Khalidah Khalid Nasser, Khalidah Khalid Nasser, Khalidah Khalid Nasser, Jumana Yousuf Al-Aama, Jumana Yousuf Al-Aama, Noor Ahmad Shaik, Noor Ahmad Shaik, Omar Ibrahim Saadah, Omar Ibrahim Saadah, Ramu Elango, Ramu Elango

    Published 2022
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  16. 76
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    Fenofibrate Inhibits Subretinal Fibrosis Through Suppressing TGF‐β-Smad2/3 signaling and Wnt signaling in Neovascular Age‐Related Macular Degeneration by Qian Chen, Qian Chen, Nan Jiang, Yuhan Zhang, Sihao Ye, Xu Liang, Xin Wang, Xiang Lin, Rongrong Zong, Haoyu Chen, Zuguo Liu, Zuguo Liu

    Published 2020
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  17. 77
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    Predicting human disease mutations and identifying drug targets from mouse gene knockout phenotyping campaigns by Robert Brommage, David R. Powell, Peter Vogel

    Published 2019
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  18. 78
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    SOCS3 deficiency in leptin receptor-expressing cells mitigates the development of pregnancy-induced metabolic changes by Thais T. Zampieri, Angela M. Ramos-Lobo, Isadora C. Furigo, João A.B. Pedroso, Daniella C. Buonfiglio, Jose Donato Jr

    Published 2015
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  19. 79
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    Development of tooth regenerative medicine strategies by controlling the number of teeth using targeted molecular therapy by Katsu Takahashi, Honoka Kiso, Akiko Murashima-Suginami, Yoshihito Tokita, Manabu Sugai, Yasuhiko Tabata, Kazuhisa Bessho

    Published 2020
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  20. 80
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    Mouse tissue harvest-induced hypoxia rapidly alters the in vivo metabolome, between-genotype metabolite level differences, and 13C-tracing enrichments by Adam J. Rauckhorst, Nicholas Borcherding, Daniel J. Pape, Alora S. Kraus, Diego A. Scerbo, Eric B. Taylor

    Published 2022
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