Search Results - "mTOR"

Esculetin Alleviates Inflammation, Oxidative Stress and Apoptosis in Intestinal Ischemia/Reperfusion Injury via Targeting SIRT3/AMPK/mTOR Signaling and Regulating Autophagy by Shen X, Shi H, Chen X, Han J, Liu H, Yang J, Shi Y, Ma J

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Sotetsuflavone Induces Autophagy in Non-Small Cell Lung Cancer Through Blocking PI3K/Akt/mTOR Signaling Pathway in Vivo and in Vitro by Shaohui Wang, Shaohui Wang, Shaohui Wang, Xiaoling Xu, Yanlan Hu, Yanlan Hu, Tao Lei, Tongxiang Liu, Tongxiang Liu

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Network Pharmacology and Experimental Evidence Reveal Dioscin Suppresses Proliferation, Invasion, and EMT via AKT/GSK3b/mTOR Signaling in Lung Adenocarcinoma by Mao W, Yin H, Chen W, Zhao T, Wu S, Jin H, Du B, Tan Y, Zhang R, He Y

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The Role of Green Tea Catechin Epigallocatechin Gallate (EGCG) and Mammalian Target of Rapamycin (mTOR) Inhibitor PP242 (Torkinib) in the Treatment of Spinal Cord Injury by Lucia Machova Urdzikova, Veronika Cimermanova, Kristyna Karova, Jose Dominguez, Katerina Stepankova, Michaela Petrovicova, Katerina Havelikova, Chirag D. Gandhi, Meena Jhanwar-Uniyal, Pavla Jendelova

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Danlou Tablet Activates Autophagy of Vascular Adventitial Fibroblasts Through PI3K/Akt/mTOR to Protect Cells From Damage Caused by Atherosclerosis by Li Wang, Tong Wu, Chunying Si, He Wang, Ke Yue, Shasha Shang, Xiaohui Li, Yushan Chen, Huaimin Guan

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Dorsal Root Ganglion Maintains Stemness of Bone Marrow Mesenchymal Stem Cells by Enhancing Autophagy through the AMPK/mTOR Pathway in a Coculture System by Shuaishuai Zhang, Junqin Li, Huijie Jiang, Yi Gao, Pengzhen Cheng, Tianqing Cao, Donglin Li, Jimeng Wang, Yue Song, Bin Liu, Hao Wu, Chunmei Wang, Liu Yang, Guoxian Pei

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Local intra-articular injection of resveratrol delays cartilage degeneration in C57BL/6 mice by inducing autophagy via AMPK/mTOR pathway by Na Qin, Liwei Wei, Wuyin Li, Wei Yang, Litao Cai, Zhuang Qian, Shufang Wu

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Urolithin A attenuates osteoclast differentiation and compensates for ovariectomy-induced bone loss in mice by inhibiting PI3K/AKT/mTOR signaling pathway by Wenyun Zhou, Weijun Zhou, Zibin Zhou, Yonghao Bi, Zhigao Zhou, Shaozhe Chen, Zihong Lin, Jiajie Ye, Gang Xie, Wenjie Liu, Dantao Xie, Zhen Lian, Ruiwu Zheng, Xianghua Hu, Xinjia Wang, Guixin Yuan, Guanfeng Yao

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Niuhuang (Bovis Calculus)-Shexiang (Moschus) combination induces apoptosis and inhibits proliferation in hepatocellular carcinoma via PI3K/AKT/mTOR pathway by Ning Dimin, Deng Zhe, Wu Yongrong, Mei Si, Teng Yongjie, Zhou Qing, Tian Xuefei

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Pretreatment of Huoxue Jiedu Formula Ameliorates Myocardial Ischaemia/Reperfusion Injury by Decreasing Autophagy via Activation of the PI3K/AKT/mTOR Pathway by Linzi Long, Linzi Long, Zikai Yu, Zikai Yu, ShengJun Chen, ShengJun Chen, Jiarui Wu, Yingying Liu, Jun Peng, Hua Qu, Hua Qu, Changgeng Fu, Changgeng Fu

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Flavonoids' Effects on <i>Caenorhabditis elegans'</i> Longevity, Fat Accumulation, Stress Resistance and Gene Modulation Involve mTOR, SKN-1 and DAF-16 by María Alejandra Guerrero-Rubio, Samanta Hernández-García, Francisco García-Carmona, Fernando Gandía-Herrero

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A phase I study of a dual PI3-kinase/mTOR inhibitor BEZ235 in adult patients with relapsed or refractory acute leukemia by Fabian Lang, Lydia Wunderle, Susanne Badura, Eberhard Schleyer, Monika Brüggemann, Hubert Serve, Susanne Schnittger, Nicola Gökbuget, Heike Pfeifer, Sebastian Wagner, Kevin Ashelford, Gesine Bug, Oliver G. Ottmann

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Acteoside and ursolic acid synergistically protects H2O2-induced neurotrosis by regulation of AKT/mTOR signalling: from network pharmacology to experimental validation by Yan-Jie Qu, Min-Rui Ding, Chao Gu, Li-Min Zhang, Rong-Rong Zhen, Jin-Fang Chen, Bing Hu, Hong-Mei An

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Circulating extracellular vesicles derived from tumor endothelial cells hijack the local and systemic anti-tumor immune response: Role of mTOR/G-CSF pathway by Malvina Koni, Tatiana Lopatina, Cristina Grange, Alessandro Sarcinella, Massimo Cedrino, Stefania Bruno, Fabrizio Buffolo, Saveria Femminò, Giovanni Camussi, Maria Felice Brizzi

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Tempol Protects Against Acute Renal Injury by Regulating PI3K/Akt/mTOR and GSK3β Signaling Cascades and Afferent Arteriolar Activity by Gensheng Zhang, Qin Wang, Wenwen Wang, Minghua Yu, Suping Zhang, Nan Xu, Suhan Zhou, Xiaoyun Cao, Xiaodong Fu, Zufu Ma, Ruisheng Liu, Jianhua Mao, En Yin Lai

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Thymoquinone Potentiates the Effect of Phenytoin against Electroshock-Induced Convulsions in Rats by Reducing the Hyperactivation of m-TOR Pathway and Neuroinflammation: Evidence from In Vivo, In Vitro and Computational Studies by Faheem Hyder Pottoo, Mohammed Salahuddin, Firdos Alam Khan, Fadhel Alomar, Marwa Abdullah AL Dhamen, Abrar Fouad Alhashim, Hawra Hussain Alqattan, Mohamed S. Gomaa, Mohammad N. Alomary

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Nuciferine induces autophagy to relieve vascular cell adhesion molecule 1 activation via repressing the Akt/mTOR/AP1 signal pathway in the vascular endothelium by Haibin Wei, Haibin Wei, Haibin Wei, Yujie Yin, Wenwen Yang, Jinyan Zhu, Lin Chen, Rui Guo, Zhen Yang, Songtao Li, Songtao Li

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Xiaojianzhong decoction attenuates aspirin-induced gastric mucosal injury via the PI3K/AKT/mTOR/ULK1 and AMPK/ULK1 pathways by Ting Chen, Shengchuan Bao, Juan Chen, Jiaxiang Zhang, Hailiang Wei, Xin Hu, Yan Liang, Jingtao Li, Shuguang Yan

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Sodium-Glucose CoTransporter-2 Inhibitor Empagliflozin Ameliorates Sunitinib-Induced Cardiac Dysfunction via Regulation of AMPK-mTOR Signaling Pathway-Mediated Autophagy by Changzhen Ren, Changzhen Ren, Kaiqiang Sun, Yanda Zhang, Yangxi Hu, Bowen Hu, Jian Zhao, Zhiqing He, Ru Ding, Weizhong Wang, Chun Liang

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Ginsenoside Rg3 Attenuates Lipopolysaccharide-Induced Acute Lung Injury via MerTK-Dependent Activation of the PI3K/AKT/mTOR Pathway by Jing Yang, Senyang Li, Luyao Wang, Fen Du, Xiaoliu Zhou, Qiqi Song, Junlong Zhao, Rui Fang

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