Search Results - "mTOR"

13-Acetoxysarcocrassolide induces apoptosis in human hepatocellular carcinoma cells through mitochondrial dysfunction and suppression of the PI3K/AKT/mTOR/p70S6K signalling pathway by Chang-Min Hsu, Jen-Jie Lin, Jui-Hsin Su, Chih-I Liu

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(+)-Panduratin A induces PANC-1 human pancreatic cancer cell death preferentially under nutrient starvation by inhibiting PI3K/Akt/mTOR/autophagy signaling pathway by Sijia Sun, Min Jo Kim, Ashraf M. Omar, Nguyen Duy Phan, Suresh Awale

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Ethyl Acetate Extract of Selaginella doederleinii Hieron Induces Cell Autophagic Death and Apoptosis in Colorectal Cancer via PI3K-Akt-mTOR and AMPKα-Signaling Pathways by Shaoguang Li, Shaoguang Li, Shaoguang Li, Xuewen Wang, Xuewen Wang, Xuewen Wang, Gang Wang, Gang Wang, Gang Wang, Peiying Shi, Shilan Lin, Shilan Lin, Shilan Lin, Dafen Xu, Dafen Xu, Dafen Xu, Bing Chen, Bing Chen, Bing Chen, Ailin Liu, Ailin Liu, Ailin Liu, Liying Huang, Xinhua Lin, Xinhua Lin, Xinhua Lin, Hong Yao, Hong Yao, Hong Yao, Hong Yao

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Melatonin Mitigates Cisplatin-Induced Ovarian Dysfunction via Altering Steroidogenesis, Inflammation, Apoptosis, Oxidative Stress, and PTEN/PI3K/Akt/mTOR/AMPK Signaling Pathway in Female Rats by Amal Al-Shahat, Mohey A. E. Hulail, Nada M. M. Soliman, Tarek Khamis, Liana Mihaela Fericean, Ahmed Hamed Arisha, Rania S. Moawad

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Osthole exhibits an antitumor effect in retinoblastoma through inhibiting the PI3K/AKT/mTOR pathway via regulating the hsa_circ_0007534/miR-214-3p axis by Xiufang Lv, Haojiang Yang, Hui Zhong, Li He, Li Wang

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Gene Expression Profiling and Protein Analysis Reveal Suppression of the C-Myc Oncogene and Inhibition JAK/STAT and PI3K/AKT/mTOR Signaling by Thymoquinone in Acute Myeloid Leukemia Cells by Belal Almajali, Muhammad Farid Johan, Abdullah Saleh Al-Wajeeh, Wan Rohani Wan Taib, Imilia Ismail, Maysa Alhawamdeh, Nafe M. Al-Tawarah, Wisam Nabeel Ibrahim, Futoon Abedrabbu Al-Rawashde, Hamid Ali Nagi Al-Jamal

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Retraction Note: Effects of Panax notoginseng saponins on severe acute pancreatitis through the regulation of mTOR/Akt and caspase-3 signaling pathway by upregulating miR-181b expression in rats by Ming-wei Liu, Rui Wei, Mei-xian Su, Hui Li, Tian-wen Fang, Wei Zhang

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Corosolic Acid Protects Rat Chondrocytes Against IL-1β-Induced ECM Degradation by Activating Autophagy via PI3K/AKT/mTOR Pathway and Ameliorates Rat Osteoarthritis by Han H, Chen M, Li Z, Zhou S, Wu Y, Wei J

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Epithelial Cells Attenuate Toll-Like Receptor-Mediated Inflammatory Responses in Monocyte-Derived Macrophage-Like Cells to Mycobacterium tuberculosis by Modulating the PI3K/Akt/mTOR Signaling Pathway by Yi Yang, Yingfei Sun, Jinrui Xu, Kangda Bao, Meihui Luo, Xiaoming Liu, Yujiong Wang

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The WT1/MVP-Mediated Stabilization on mTOR/AKT Axis Enhances the Effects of Cisplatin in Non-small Cell Lung Cancer by a Reformulated Yu Ping Feng San Herbal Preparation by Jian-Shu Lou, Jian-Shu Lou, Yi-Teng Xia, Yi-Teng Xia, Huai-You Wang, Huai-You Wang, Xiang-Peng Kong, Xiang-Peng Kong, Ping Yao, Tina T. X. Dong, Tina T. X. Dong, Zhong-Yu Zhou, Zhong-Yu Zhou, Karl W. K. Tsim, Karl W. K. Tsim

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The Botanical Drug PBI-05204, a Supercritical CO2 Extract of Nerium Oleander, Inhibits Growth of Human Glioblastoma, Reduces Akt/mTOR Activities, and Modulates GSC Cell-Renewal Properties by Alessandro Colapietro, Peiying Yang, Alessandra Rossetti, Andrea Mancini, Flora Vitale, Stefano Martellucci, Stefano Martellucci, Tara L. Conway, Sharmistha Chakraborty, Francesco Marampon, Vincenzo Mattei, Giovanni Luca Gravina, Giovanni Luca Gravina, Assunta Leda Biordi, Daoyan Wei, Robert A. Newman, Claudio Festuccia

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Melatonin Prevents Oxidative Stress-Induced Mitochondrial Dysfunction and Apoptosis in High Glucose-Treated Schwann Cells via Upregulation of Bcl2, NF-κB, mTOR, Wnt Signalling Pathways by Yee Lian Tiong, Khuen Yen Ng, Rhun Yian Koh, Gnanajothy Ponnudurai, Soi Moi Chye

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Inhibitory effects of ursolic acid from Bushen Yijing Formula on TGF-β1-induced human umbilical vein endothelial cell fibrosis via AKT/mTOR signaling and Snail gene by Ke Zhu, Cuixiang Cao, Jiaqi Huang, Zixuan Cheng, Donghai Li, Xiuting Liu, Yueping Mao, Qing Qi

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Retrospective immunophenotypical evaluation of MET, PD-1/PD-L1, and mTOR pathways in primary tumors and pulmonary metastases of renal cell carcinoma: the RIVELATOR study addresses the issue of biomarkers heterogeneity by Melissa Bersanelli, Letizia Gnetti, Francesco Paolo Pilato, Elena Varotti, Federico Quaini, Nicoletta Campanini, Elena Rapacchi, Roberta Camisa, Paolo Carbognani, Enrico Maria Silini, Michele Rusca, Francesco Leonardi, Umberto Maestroni, Mimma Rizzo, Matteo Brunelli, Sebastiano Buti, Luca Ampollini

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The Flavagline Compound 1-(2-(dimethylamino)acetyl)-Rocaglaol Induces Apoptosis in K562 Cells by Regulating the PI3K/Akt/mTOR, JAK2/STAT3, and MAPK Pathways by Yang X, Wu X, Wu X, Huang L, Song J, Yuan C, He Z, Li Y

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Metformin-Induced MicroRNA-34a-3p Downregulation Alleviates Senescence in Human Dental Pulp Stem Cells by Targeting CAB39 through the AMPK/mTOR Signaling Pathway by Shuo Zhang, Rong Zhang, Pengyan Qiao, Xiaocao Ma, Rongjian Lu, Feifan Wang, Chuanjie Li, Lingling E, Hongchen Liu

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Active fraction (HS7) from Taiwanofungus camphoratus inhibits AKT-mTOR, ERK and STAT3 pathways and induces CDK inhibitors in CL1-0 human lung cancer cells by I-Chun Lai, Gi-Ming Lai, Jyh-Ming Chow, Hsin-Lun Lee, Chuan-Feng Yeh, Chi-Han Li, Jiann-Long Yan, Shuang-En Chuang, Jacqueline Whang-Peng, Kuan-Jen Bai, Chih-Jung Yao

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Total saponins of Bolbostemma paniculatum (maxim.) Franquet exert antitumor activity against MDA-MB-231 human breast cancer cells via inhibiting PI3K/Akt/mTOR pathway by Jian-Wei Dou, Rong-Guo Shang, Xiao-Qin Lei, Kang-Le Li, Zhan-Zi Guo, Kai Ye, Xiao-Juan Yang, Yu-Wei Li, Yun-Yun Zhou, Jia Yao, Qian Huang

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Anti-Tumor Xanthones from Garcinia nujiangensis Suppress Proliferation, and Induce Apoptosis via PARP, PI3K/AKT/mTOR, and MAPK/ERK Signaling Pathways in Human Ovarian Cancers Cells by Tang Z, Lu L, Xia Z

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Alisertib induces cell cycle arrest and autophagy and suppresses epithelial-to-mesenchymal transition involving PI3K/Akt/mTOR and sirtuin 1-mediated signaling pathways in human pancreatic cancer cells by Wang F, Li H, Yan XG, Zhou ZW, Yi ZG, He ZX, Pan ST, Yang YX, Wang ZZ, Zhang X, Yang T, Qiu JX, Zhou SF

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