Résultats de la recherche - "molecule"

Utilization of physiologically‐based pharmacokinetic model to assess disease‐mediated therapeutic protein‐disease‐drug interaction in immune‐mediated inflammatory diseases... par Lujing Wang, Yang Chen, Wangda Zhou, Xin Miao, Honghui Zhou

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Comprehensive spectroscopic and computational insight into the binding of vanillin with human transferrin: targeting neuroinflammation in Alzheimer's disease therapeutics par Mohammed Alrouji, Sabina Yasmin, Fahad A. Alhumaydhi, Sharaf E. Sharaf, Moyad Shahwan, Moyad Shahwan, Mohammad Furkan, Rizwan Hasan Khan, Anas Shamsi

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Salidroside Protects Acute Kidney Injury in Septic Rats by Inhibiting Inflammation and Apoptosis par Fan H, Su B, Le J, Zhu J

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Metabolomic Analysis of the Effects of Adipose-Derived Mesenchymal Stem Cell Treatment on Rats With Sepsis-Induced Acute Lung Injury par Yuqing Cui, Shaohua Liu, Xiaojuan Zhang, Xianfei Ding, Xiaoguang Duan, Zijia Zhu, Ji Zhang, Huoyan Liang, Dong Wang, Guojun Zhang, Zujiang Yu, Jianjun Yang, Tongwen Sun

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Augmented Efficacy of Uttroside B over Sorafenib in a Murine Model of Human Hepatocellular Carcinoma par Mundanattu Swetha, Chenicheri K. Keerthana, Tennyson P. Rayginia, Lekshmi R. Nath, Nair Hariprasad Haritha, Anwar Shabna, Kalishwaralal Kalimuthu, Arun K. Thangarasu, Sreekumar U. Aiswarya, Somaraj Jannet, Sreekumar Pillai, Kuzhuvelil B. Harikumar, Sankar Sundaram, Nikhil Ponnoor Anto, Dee H. Wu, Ravi S. Lankalapalli, Rheal Towner, Noah Isakov, Sathyaseelan S. Deepa, Ruby John Anto

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Characterisation of Drug Delivery Efficacy Using Microstructure-Assisted Application of a Range of APIs par Raha Rahbari, Ionut Ichim, Ryan Bamsey, Jemma Burridge, Owen J. Guy, John Bolodeoku, Michael Graz

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The therapeutic effects of Rho-ROCK inhibitors on CNS disorders par Takekazu Kubo, Atsushi Yamaguchi, Nobuyoshi Iwata, Toshihide Yamashita

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Extracellular HMGB1: a therapeutic target in severe pulmonary inflammation including COVID-19? par Ulf Andersson, William Ottestad, Kevin J. Tracey

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Machine-Learning Guided Discovery of Bioactive Inhibitors of PD1-PDL1 Interaction par Sachin P. Patil, Elena Fattakhova, Jeremy Hofer, Michael Oravic, Autumn Bender, Jason Brearey, Daniel Parker, Madison Radnoff, Zackary Smith

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Attenuation of Circulating Trimethylamine N-Oxide Prevents the Progression of Cardiac and Renal Dysfunction in a Rat Model of Chronic Cardiorenal Syndrome par Deling Zou, Yanyu Li, Guangping Sun

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Silybin A enhances circadian clock by targeting CRY1 and disrupting its interaction with CLOCK par Weijie Bian, Weilin Zhang, Hao Liang, Xiaowen Xie, Luhua Lai

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PLGA Nanoparticles Containing VCAM-1 Inhibitor Succinobucol and Chemotherapeutic Doxorubicin as Therapy against Primary Tumors and Their Lung Metastases par Jie Wang, Fengling Wang, Dandan Xie, Min Zhou, Jiaxing Liao, Hongliang Wu, Yue Dai, Jingbin Huang, Yu Zhao

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Drug-induced psoriasis: clinical perspectives par Balak DMW, Hajdarbegovic E

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Ketogenic diet administration to mice after a high-fat-diet regimen promotes weight loss, glycemic normalization and induces adaptations of ketogenic pathways in liver and kidney par Souad Nasser, Thomas Solé, Nathalie Vega, Thierry Thomas, Aneta Balcerczyk, Maura Strigini, Luciano Pirola

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Activation of ERK-p53 and ERK-Mediated Phosphorylation of Bcl-2 Are Involved in Autophagic Cell Death Induced by the c-Met Inhibitor SU11274 in Human Lung Cancer A549 Cells par Ying Liu, Ying Yang, Yuan-Chao Ye, Qi-Feng Shi, Kuan Chai, Shin-ichi Tashiro, Satoshi Onodera, Takashi Ikejima

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Inhibition of Nur77 expression and translocation by compound B6 reduces ER stress and alleviates cigarette smoke-induced inflammation and injury in bronchial epithelial cells par Chenli Chang, Fengming He, Mingtao Ao, Jun Chen, Tao Yu, Weiyu Li, Baicun Li, Meijuan Fang, Ting Yang

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Impairment of exocytotic transmitter release by decynium-22 through an inhibition of ion channels par Gabriele Haar, Katsiaryna Hrachova, Tanja Wagner, Stefan Boehm, Klaus Schicker

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Neuropharmacological characteristics of antidepressant action of a new 3-substituted thietane-1,1-dioxide derivative par Irina L. Nikitina, Gulnara G. Gaisina

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Extrinsic apoptotic pathways: A new potential "Target" for more sufficient therapy in a case of cutaneous anaplastic large CD30+ ALK-T--cell lymphoma par Georgi Tchernev, José Carlos Cardoso, Lubomir Arseniev, Hiroyuki Okamoto

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Phenotypic chemical screening using a zebrafish neural crest EMT reporter identifies retinoic acid as an inhibitor of epithelial morphogenesis par Laura Jimenez, Jindong Wang, Monique A. Morrison, Clifford Whatcott, Katherine K. Soh, Steven Warner, David Bearss, Cicely A. Jette, Rodney A. Stewart

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