Search Results - "molecule"

CRISPR/SaCas9 mutagenesis of stromal interaction molecule 1 in proopiomelanocortin neurons increases glutamatergic excitability and protects against diet-induced obesity by Jian Qiu, Martha A. Bosch, Todd L. Stincic, Avery C. Hunker, Larry S. Zweifel, Oline K. Rønnekleiv, Martin J. Kelly

Connect to this object online.

Effect of leech-centipede medicine on improving erectile function in diabetes-induced erectile dysfunction rats via PDE5 signalling pathway-related molecules by Ji-Sheng Wang, Jun-Long Feng, Xiao Li, Zi-Long Chen, Bing-Hao Bao, Sheng Deng, Heng-Heng Dai, Fan-Chao Meng, Bin Wang, Hai-Song Li

Connect to this object online.

Design and Mechanism of Action of a New Prototype of Combi-Molecule "Programed" to Release Bioactive Species at a pH Range Akin to That of the Tumor Microenvironment by Anne-Laure La, Etienne Chatelut, Jean-Pierre Delord, Diane-Charlotte Imbs, Philippe Rochaix, Bertrand Jean-Claude, Ben Allal

Connect to this object online.

A hypothermia mimetic molecule (zr17-2) reduces ganglion cell death, gliosis, and electroretinogram distortion in male rats subjected to perinatal asphyxia by Manuel Rey-Funes, Manuel Rey-Funes, Juan Carlos Fernández, Rafael Peláez, Manuel Soliño, Daniela S. Contartese, Nicolás S. Ciranna, Ronan Nakamura, Ronan Nakamura, Aníbal Sarotto, Verónica B. Dorfman, José M. Zapico, Ana Ramos, Beatriz de Pascual-Teresa, Juan José López-Costa, Juan José López-Costa, Ignacio M. Larrayoz, Alfredo Martínez, César Fabián Loidl, César Fabián Loidl

Connect to this object online.

Optimizing the enzymatic release of MMAE from isoDGR-based small molecule drug conjugate by incorporation of a GPLG-PABC enzymatically cleavable linker by Marco Zambra, Ivan Ranđelović, Francesco Talarico, Adina Borbély, Laura Svajda, Laura Svajda, József Tóvári, Gábor Mező, Gábor Mező, Lizeth Bodero, Sveva Colombo, Sveva Colombo, Federico Arrigoni, Elettra Fasola, Silvia Gazzola, Umberto Piarulli

Connect to this object online.

On-target and direct modulation of alloreactive T cells by a nanoparticle carrying MHC alloantigen, regulatory molecules and CD47 in a murine model of alloskin transplantation by Khawar Ali Shahzad, Xin Wan, Lei Zhang, Weiya Pei, Aifeng Zhang, Muhammad Younis, Wei Wang, Chuanlai Shen

Connect to this object online.

OA2-3 Small-molecule chemotherapeutic drugs reactivate HIV-1 via non-canonical pathways and modulate CD8 T cell response by I. Munoz-Arias, E. Hanhauser, L. Hogan, M.A. Mohsen, Kristen Hobbs, C. Thanh, E. Gibson, S.G. Deeks, S.K. Pillai, T.J. Henrich

Connect to this object online.

Interaction of Signaling Lymphocytic Activation Molecule Family 1 (SLAMF1) receptor with Trypanosoma cruzi is strain-dependent and affects NADPH oxidase expression and activity. by Cristina Poveda, Alfonso Herreros-Cabello, Francisco Callejas-Hernández, Jesús Osuna-Pérez, María C Maza, Carlos Chillón-Marinas, Jossela Calderón, Konstantinos Stamatakis, Manuel Fresno, Núria Gironès

Connect to this object online.

Optical Bioimaging: From Living Tissue to a Single Molecule: Calcium Imaging in Blood Vessel In Situ Employing Two-Photon Excitation Fluorescence Microscopy by Hisayuki Ohata, Hideyuki Yamada, Takeharu Niioka, Masayuki Yamamoto, Kazutaka Momose

Connect to this object online.

Changes in the levels of marker molecules salivary α-amylase and cortisol as a stress response to everyday activities of general practitioners in rural areas of the Republic of Bulgaria by Adolf Alakidi, Iliyan Dimitrov, Anelia Bivolarska, Vanina Mihaylova

Connect to this object online.

1,2,4-Triazole-Tethered Indolinones as New Cancer-Fighting Small Molecules Targeting VEGFR-2: Synthesis, Biological Evaluations and Molecular Docking by Ahmed E. Elsawi, Mai I. Shahin, Hager A. Elbendary, Tarfah Al-Warhi, Fatma E. Hassan, Wagdy M. Eldehna

Connect to this object online.

Soluble Intercellular Adhesion Molecule- (sICAM-) 1, Thrombospondin-1, and Vinculin for the Identification of Septic Shock Patients Suffering from an Invasive Fungal Infection by Sebastian O. Decker, Anne Incamps, Annette Sigl, Florian Uhle, Thomas Bruckner, Alexandra Heininger, Stefan Zimmermann, Christophe Hirtz, Markus A. Weigand, Thorsten Brenner

Connect to this object online.

Gestational Tissue-Derived Human Mesenchymal Stem Cells Use Distinct Combinations of Bioactive Molecules to Suppress the Proliferation of Human Hepatoblastoma and Colorectal Cancer Cells by Nitchapon Paiboon, Witchayaporn Kamprom, Sirikul Manochantr, Chairat Tantrawatpan, Duangrat Tantikanlayaporn, Sittiruk Roytrakul, Pakpoom Kheolamai

Connect to this object online.

cΔlog kwIAM: can we afford estimation of small molecules' blood-brain barrier passage based upon in silico phospholipophilicity? by Lucia Grumetto, Giacomo Russo

Connect to this object online.

Content of middle mass molecules and erythrocyte intoxication index in blood while experimental allergic alveolitis under adrenalin myocardial injury and correction of the injury by thiotriazoline by V. B. Pyndus, T. O. Pyndus

Connect to this object online.

Small molecule purine and pseudopurine derivatives: synthesis, cytostatic evaluations and investigation of growth inhibitory effect in non-small cell lung cancer A549 by Andrea Bistrović, Petra Grbčić, Anja Harej, Mirela Sedić, Sandra Kraljević-Pavelić, Sanja Koštrun, Janez Plavec, Damjan Makuc, Silvana Raić-Malić

Connect to this object online.

SB216763, a selective small molecule inhibitor of glycogen synthase kinase-3, improves bleomycin-induced pulmonary fibrosis via activating autophagy by Hong Liu, Su Mi, Zhe Li, Xiaoxi Lv, Ke Li, Fang Hua, Zhuowei Hu

Connect to this object online.

The Discovery of GIT1/β-Pix Inhibitors: Virtual Screening and Biological Evaluation of New Small-molecule Compounds with Anti-invasion Effect in Gastrointestinal Neoplasms by Wang C, Gu J, Li H, Zhao B, Yu T, Guo CL, Huang M, Jiang W, Ouyang Q

Connect to this object online.

Content of middle mass molecules and erythrocyte intoxication index in blood while experimental allergic alveolitis under adrenalin myocardial injury and correction of the injury by thiotriazoline by V. B. Pyndus, T. O. Pyndus

Connect to this object online.

A small-molecule inhibitor of MDMX suppresses cervical cancer cells via the inhibition of E6-E6AP-p53 axis by Jingwen Zhang, Guohua Yu, Yanting Yang, Yingjie Wang, Mengqi Guo, Qikun Yin, Chunhong Yan, Jingwei Tian, Fenghua Fu, Hongbo Wang

Connect to this object online.