Search Results - "pharmacodynamics"

Preclinical Studies in the mdx Mouse Model of Duchenne Muscular Dystrophy with the Histone Deacetylase Inhibitor Givinostat by Silvia Consalvi, Chiara Mozzetta, Paolo Bettica, Massimiliano Germani, Francesco Fiorentini, Francesca Del Bene, Maurizio Rocchetti, Flavio Leoni, Valmen Monzani, Paolo Mascagni, Pier Lorenzo Puri, Valentina Saccone

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Evaluation of sunobinop for next-day residual effects in healthy participants by Alessandra Cipriano, Ram P. Kapil, Mingyan Zhou, Manjunath S. Shet, Stephen C. Harris, Glen Apseloff, Garth T. Whiteside

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Atorvastatin-loaded micelles with bone-targeted ligand for the treatment of osteoporosis by Yonghui Xie, Xueying Tan, Jian Huang, Hongwei Huang, Ping Zou, Jingbo Hu

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Network bioinformatics analysis provides insight into drug repurposing for COVID-19 by Xu Li, Jinchao Yu, Zhiming Zhang, Jing Ren, Alex E. Peluffo, Wen Zhang, Yujie Zhao, Jiawei Wu, Kaijing Yan, Daniel Cohen, Wenjia Wang

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A Novel Derivative of Thioridazine Shows Low Toxicity and Efficient Activity against Gram-Positive Pathogens by Nadia S. Jørgensen, Lasse Saaby, Anne M. Andersson, Sofie Kromann, Ehsan Sheikhsamani, Anders Permin, Troels Ronco, Søren W. Svenningsen, Jørn B. Christensen, Rikke H. Olsen

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Epidemiology of potential drug-drug interactions in elderly population admitted to critical care units of Peshawar, Pakistan by Faisal Shakeel, Muhammad Aamir, Ahmad Farooq Khan, Tayyiba Nader Khan, Samiullah Khan

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Drug Interactions With New Synthetic Opioids by Clara Pérez-Mañá, Clara Pérez-Mañá, Esther Papaseit, Esther Papaseit, Francina Fonseca, Francina Fonseca, Adriana Farré, Adriana Farré, Marta Torrens, Marta Torrens, Magi Farré, Magi Farré

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A Minimal PBPK/PD Model with Expansion-Enhanced Target-Mediated Drug Disposition to Support a First-in-Human Clinical Study Design for a FLT3L-Fc Molecule by Iraj Hosseini, Brett Fleisher, Jennifer Getz, Jérémie Decalf, Mandy Kwong, Meric Ovacik, Travis W. Bainbridge, Christine Moussion, Gautham K. Rao, Kapil Gadkar, Amrita V. Kamath, Saroja Ramanujan

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Exposure-response analysis of adverse events associated with molibresib and its active metabolites in patients with solid tumors by Anu Shilpa Krishnatry, Eva Hanze, Tim Bergsma, Arindam Dhar, Marita Prohn, Geraldine Ferron‐Brady

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Physiologically-based pharmacokinetic modelling and dosing evaluation of gentamicin in neonates using PhysPK by Hinojal Zazo, Hinojal Zazo, Eduardo Lagarejos, Manuel Prado-Velasco, Sergio Sánchez-Herrero, Jenifer Serna, Almudena Rueda-Ferreiro, Ana Martín-Suárez, Ana Martín-Suárez, M. Victoria Calvo, M. Victoria Calvo, Jonás Samuel Pérez-Blanco, Jonás Samuel Pérez-Blanco, José M. Lanao, José M. Lanao

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Novel Peripherally Restricted Cannabinoid 1 Receptor Selective Antagonist TXX-522 with Prominent Weight-Loss Efficacy in Diet Induced Obese Mice by Wei Chen, Wei Chen, Fengchun Shui, Fengchun Shui, Cheng Liu, Xinbo Zhou, Xinbo Zhou, Wei Li, Wei Li, Zhibing Zheng, Zhibing Zheng, Wei Fu, Lili Wang, Lili Wang

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Inhibition of sirtuin 2 with sulfobenzoic acid derivative AK1 is non-toxic and potentially neuroprotective in a mouse model of frontotemporal dementia by Tara Leigh Spires-Jones, Leora M Fox, Leora M Fox, Anete eRozkalne, Rose ePitstick, George A Carlson, Aleksey G. Kazantsev

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High-Throughput Chinmedomics Strategy Discovers the Quality Markers and Mechanisms of Wutou Decoction Therapeutic for Rheumatoid Arthritis by Taiping Li, Taiping Li, Fangfang Wu, Aihua Zhang, Hui Dong, Ihsan Ullah, Hao Lin, Jianhua Miao, Hui Sun, Ying Han, Yanmei He, Xijun Wang, Xijun Wang

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The Role of Adherence Thresholds for Development and Performance Aspects of a Prediction Model for Direct Oral Anticoagulation Adherence by Carmen Ruff, Ludmila Koukalova, Walter E. Haefeli, Andreas D. Meid

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Identifying potential anti-COVID-19 pharmacological components of traditional Chinese medicine Lianhuaqingwen capsule based on human exposure and ACE2 biochromatography screening by Xiaofei Chen, Yunlong Wu, Chun Chen, Yanqiu Gu, Chunyan Zhu, Suping Wang, Jiayun Chen, Lei Zhang, Lei Lv, Guoqing Zhang, Yongfang Yuan, Yifeng Chai, Mingshe Zhu, Caisheng Wu

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UPLC-ESI-MS/MS and HPTLC Method for Quantitative Estimation of Cytotoxic Glycosides and Aglycone in Bioactivity Guided Fractions of Solanum nigrum L. by Karishma Chester, Sarvesh Paliwal, Washim Khan, Sayeed Ahmad

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Chloroquine dosage regimen simulation for pediatric patients with coronavirus disease 2019 by Kiatkriangkrai Koyratkoson, Nattapong Tidwong, Suwida Tangtrakultham, Preecha Montakantikul

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The OBTAINS study: A nationwide cross-sectional survey on the implementation of extended or continuous infusion of β-lactams and vancomycin among neonatal sepsis patients in China by Pengxiang Zhou, Pengxiang Zhou, Pengxiang Zhou, Pengxiang Zhou, Yinchu Cheng, Yinchu Cheng, Guangna Cao, Yan Xing, Suodi Zhai, Suodi Zhai, Xiaomei Tong, Kehu Yang, Kehu Yang

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PLGA-based nanoparticles for the treatment of cancer: current strategies and perspectives by Maria Alvi, Azka Yaqoob, Kanwal Rehman, Syed Muhammad Shoaib, Muhammad Sajid Hamid Akash

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Saikosaponin D: review on the antitumour effects, toxicity and pharmacokinetics by Piao Zhou, Wei Shi, Xiao-Yan He, Quan-Yu Du, Fei Wang, Jing Guo

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