Search Results - "pharmacodynamics"

Prospective Validation and Refinement of a Population Pharmacokinetic Model of Fludarabine in Children and Young Adults Undergoing Hematopoietic Cell Transplantation by Jordan T. Brooks, Belen P. Solans, Ying Lu, Sandhya Kharbanda, Christopher C. Dvorak, Nahal Lalefar, Susie Long, Ashish O. Gupta, Biljana Horn, Jatinder K. Lamba, Liusheng Huang, Beth Apsel-Winger, Ron J. Keizer, Rada Savic, Janel Long-Boyle

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In Vitro/In Vivo Correlation of Two Extended-Release Cilostazol Formulations by Kyoung Ah Min, Na Young Kim, Min Jeong Jin, Doyeon Kim, Yoonseo Ma, Sandeep Karna, Young-Joon Park

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On placental and lactational transfer of IgG‐based therapeutic proteins - Current understanding and knowledge gaps from a clinical pharmacology perspective by Daphne Guinn, Katherine Kratz, Kristie Baisden, Sarah Ridge, Sonaly McClymont, Elimika Pfuma Fletcher, Tamara Johnson, Yow‐Ming Wang

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Impact of the mouse estrus cycle on cannabinoid receptor agonist‐induced molecular and behavioral outcomes by Hye Ji J. Kim, Ayat Zagzoog, Tallan Black, Sarah L. Baccetto, Udoka C. Ezeaka, Robert B. Laprairie

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Hybrid physiologically‐based pharmacokinetic model for remdesivir: Application to SARS‐CoV‐2 by James M. Gallo

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Developing a mechanistic translational PK/PD model for a trifunctional NK cell engager to predict the first‐in‐human dose for acute myeloid leukemia by Siak‐Leng Choi, Delphine Valente, Angela Virone‐Oddos, Christine Mauriac

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Antimicrobial Activities of Aztreonam-Avibactam and Comparator Agents against Enterobacterales Analyzed by ICU and Non-ICU Wards, Infection Sources, and Geographic Regions: ATLAS P... by Denis Piérard, Elizabeth D. Hermsen, Michal Kantecki, Francis F. Arhin

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Population PK/PD modeling of low‐density lipoprotein cholesterol response in hypercholesterolemic participants following administration of bococizumab, a potent anti‐PCSK9 monoclon... by Ellen Q. Wang, Nitin Kaila, David Plowchalk, Leonid Gibiansky, Carla Yunis, Kevin Sweeney

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Integrating real‐world data to accelerate and guide drug development: A clinical pharmacology perspective by Xiaochen Zhao, Shahed Iqbal, Ivelisse L. Valdes, Mark Dresser, Sandhya Girish

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Isavuconazole Kinetic Exploration for Clinical Practice by Léa Darnaud, Fabien Lamoureux, Cendrine Godet, Sandrine Pontier, Alexia Debard, Nicolas Venisse, Pauline Martins, Didier Concordet, Peggy Gandia

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Melatonin Interaction Resulting in Severe Sedation by Brian C Foster, Kosta Cvijovic, Heather S Boon, Teresa W Tam, Rui Liu, Mano Murty, Duc Vu, Walter Jaeger, Ross T Tsuyuki, Joanne Barnes, Sunita Vohra

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Drug binding and drug-drug interaction considerations in individuals with obesity before and after bariatric surgery: A retrospective cross-sectional study by Emerita Quintina de Andrade Moura, Carolina Dumke de Siqueira, Ana Carolina Martins, Bruno Fonseca Nunes, Ana Carolina Rabello de Moraes, Fabíola Branco Filippin-Monteiro

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Felodipine in Treatment of Arterial Hypertension and Ischemic Heart Disease by O. D. Ostroumova, I. A. Alautdinova, A. I. Kochetkov, S. N. Litvinova

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Effect of ASP8062 on morphine self-administration and morphine-induced respiratory suppression in monkeys by Shinobu Akuzawa, Megumi Irie, Masayuki Kanki, Takafumi Shirakawa, Yuichiro Sato

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Study of the <span style="font-variant: small-caps">l</span>-Phenylalanine Ammonia-Lyase Penetration Kinetics and the Efficacy of Phenylalanine Catabolism Correction Using In Vitro... by Lyubov Dyshlyuk, Stanislav Sukhikh, Svetlana Noskova, Svetlana Ivanova, Alexander Prosekov, Olga Babich

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Stereoselective inhibition of the hERG1 potassium channel by Liliana eSintra Grilo, Liliana eSintra Grilo, Pierre-Alain eCarrupt, Hugues eAbriel

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Film Forming Systems for Delivery of Active Molecules into and across the Skin by Elka Touitou, Hiba Natsheh, Jana Zailer

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Predictive Simulations in Preclinical Oncology to Guide the Translation of Biologics by Shujun Dong, Ian Nessler, Anna Kopp, Baron Rubahamya, Greg M. Thurber, Greg M. Thurber, Greg M. Thurber

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Systemic Design and Evaluation of Ticagrelor-Loaded Nanostructured Lipid Carriers for Enhancing Bioavailability and Antiplatelet Activity by Gi-Ho Son, Young-Guk Na, Hyun Wook Huh, Miao Wang, Min-Ki Kim, Min-Gu Han, Jin-Ju Byeon, Hong-Ki Lee, Cheong-Weon Cho

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Development of a multiscale mechanistic modeling framework integrating differential cellular kinetics of CAR T‐cell subsets and immunophenotypes in cancer patients by Ahmed M. Salem, Ganesh M. Mugundu, Aman P. Singh

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