Search Results - "pharmacodynamics"

Population Pharmacokinetics and Model-Based Dosing Optimization of Teicoplanin in Pediatric Patients by Tao Zhang, Dan Sun, Zuocheng Shu, Ziyun Duan, Yang Liu, Qian Du, Ying Zhang, Yuzhu Dong, Taotao Wang, Sasa Hu, Hua Cheng, Yalin Dong

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Population pharmacokinetics of methylphenidate hydrochloride extended-release multiple-layer beads in pediatric subjects with attention deficit hyperactivity disorder by Teuscher NS, Adjei A, Findling RL, Greenhill LL, Kupper RJ, Wigal S

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Model‐informed drug development for immuno‐oncology agonistic anti‐GITR antibody GWN323: Dose selection based on MABEL and biologically active dose by Yan Ji, Deborah Knee, Xinhui Chen, Anhthu Dang, Jennifer Mataraza, Babette Wolf, Sherwin K. B. Sy

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In-depth LC-MS and in-vitro studies of a triterpenoid saponin capilliposide-A metabolism modulation in gut microbiota of mice by Huan Zhao, Huan Zhao, Xueli Hu, Shenghong Guan, Jinhong Cai, Xiaohan Li, Jiaxi Fang, Bo Lin, Wei Zhu, Jingkui Tian, Juan Jin, Qiang He, Qiang He, Xiaoyong Zhang

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LC-MS-based metabolomics reveals the mechanism of anti-gouty arthritis effect of Wuwei Shexiang pill by Jirui Lang, Li Li, Yunyun Quan, Ruirong Tan, Jinbiao Zhao, Min Li, Jin Zeng, Shilong Chen, Ting Wang, Yong Li, Junning Zhao, Zhujun Yin, Zhujun Yin

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Modification of sodium aescinate into a safer, more stable and effective water-soluble drug by liposome-encapsulation: an in vitro and in vivo study by Sifan Huang, Xinyu Wang, Mengmeng Liu, Zhizhe Lin, Wenqian Gu, Haili Zhao, Yanqiu Zhang, Baoyue Ding, Jiyong Liu, Xin Wu, Wei Fan, Jianming Chen

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Exploration of sodium homeostasis and pharmacokinetics in bile duct-ligated rats treated by anti-cirrhosis herbal formula plus spironolactone by Tun-Pin Hsueh, Tun-Pin Hsueh, Tun-Pin Hsueh, Tung-Hu Tsai, Tung-Hu Tsai, Tung-Hu Tsai

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Promoting Angiogenesis Effect and Molecular Mechanism of Isopropyl Caffeate (KYZ), a Novel Metabolism-Derived Candidate Drug, Based on Integrated Network Pharmacology and Transgeni... by Haotian Kong, Haotian Kong, Songsong Wang, Yougang Zhang, Yangtengjiao Zhang, Qiuxia He, Rong Dong, Xiaohui Zheng, Kechun Liu, Liwen Han

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Development of thermosensitive hydrogel of Amphotericin-B and Lactoferrin combination-loaded PLGA-PEG-PEI nanoparticles for potential eradication of ocular fungal infections: In-vi... by Sammar Fathy Elhabal, Shrouk A. Ghaffar, Raghda Hager, Nahla A. Elzohairy, Mohamed Mansour Khalifa, Passant M. Mohie, Rania A. Gad, Nasreen N. Omar, Mohammed H. Elkomy, Mohammad Ahmad Khasawneh, Nashwa Abdelaal

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Predictive Factors of Piperacillin Exposure and the Impact on Target Attainment after Continuous Infusion Administration to Critically Ill Patients by Javier Martínez-Casanova, Erika Esteve-Pitarch, Helena Colom-Codina, Víctor Daniel Gumucio-Sanguino, Sara Cobo-Sacristán, Evelyn Shaw, Kristel Maisterra-Santos, Joan Sabater-Riera, Xosé L. Pérez-Fernandez, Raül Rigo-Bonnin, Fe Tubau-Quintano, Jordi Carratalà, Ariadna Padullés-Zamora

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Patient concerns regarding antidepressant drug-drug interactions: a retrospective analysis using data from a medicines call centre by Treasure M. McGuire, Geraldine M. Moses, David M. Pache, Mieke L. van Driel, Samantha A. Hollingworth, Hyang Joo Lim, Edgar L. Poon

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Nardostachys jatamansi and levodopa combination alleviates Parkinson's disease symptoms in rats through activation of Nrf2 and inhibition of NLRP3 signaling pathways by Jiayuan Li, Jiahe Yu, Jianyou Guo, Jinfeng Liu, Guohui Wan, Xiaojia Wei, Xue Yang, Jinli Shi

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Population Pharmacokinetics of Amikacin in Patients on Veno-Arterial Extracorporeal Membrane Oxygenation by Claire Pressiat, Agathe Kudela, Quentin De Roux, Nihel Khoudour, Claire Alessandri, Hakim Haouache, Dominique Vodovar, Paul-Louis Woerther, Alice Hutin, Bijan Ghaleh, Anne Hulin, Nicolas Mongardon

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Combining antihypertensive and antihyperlipidemic agents – optimizing cardiovascular risk factor management by Zamorano J, Edwards J

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Vericiguat in combination with isosorbide mononitrate in patients with chronic coronary syndromes: The randomized, phase Ib, VISOR study by Michael Boettcher, Gerd Mikus, Dietmar Trenk, Hans‐Dirk Düngen, Frank Donath, Nikos Werner, Mahir Karakas, Nina Besche, Dominik Schulz‐Burck, Mireille Gerrits, James Hung, Corina Becker

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Generative artificial intelligence in drug discovery: basic framework, recent advances, challenges, and opportunities by Amit Gangwal, Azim Ansari, Iqrar Ahmad, Abul Kalam Azad, Vinoth Kumarasamy, Vetriselvan Subramaniyan, Vetriselvan Subramaniyan, Ling Shing Wong

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In vitro and in vivo antitumor effects of lupeol-loaded galactosylated liposomes by Jun Zhang, Xixi Hu, Guohua Zheng, Hui Yao, Huali Liang

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Quantitative Systems Pharmacology for Neuroscience Drug Discovery and Development: Current Status, Opportunities, and Challenges by Hugo Geerts, John Wikswo, Piet H. van derGraaf, Jane P.F. Bai, Chris Gaiteri, David Bennett, Susanne E. Swalley, Edgar Schuck, Rima Kaddurah‐Daouk, Katya Tsaioun, Mary Pelleymounter

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Simultaneous Semi-Mechanistic Population Pharmacokinetic Modeling Analysis of Enalapril and Enalaprilat Serum and Urine Concentrations From Child Appropriate Orodispersible Minitab... by Muhammad Faisal, Willi Cawello, Bjoern B. Burckhardt, Jan de Hoon, Stephanie Laer, LENA Consortium

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Comparative Effects of Metamizole (Dipyrone) and Naproxen on Renal Function and Prostacyclin Synthesis in Salt-Depleted Healthy Subjects - A Randomized Controlled Parallel Group St... by Lea S Blaser, Urs Duthaler, Urs Duthaler, Jamal Bouitbir, Jamal Bouitbir, Anne B Leuppi-Taegtmeyer, Anne B Leuppi-Taegtmeyer, Evangelia Liakoni, Reto Dolf, Michael Mayr, Jürgen Drewe, Stephan Krähenbühl, Stephan Krähenbühl, Stephan Krähenbühl, Manuel Haschke

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