Search Results - "pharmacodynamics"

Safety, tolerability, pharmacokinetic/pharmacodynamic characteristics of bersiporocin, a novel prolyl‐tRNA synthetase inhibitor, in healthy subjects by Min Young Park, Sungyeun Bae, Jung A Heo, Mihee Park, YuKyung Kim, Jumi Han, In‐Jin Jang, Kyung‐Sang Yu, Jaeseong Oh

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Dosing Evaluation of Ceftazidime-Avibactam in Intensive Care Unit Patients Based on Pharmacokinetic/Pharmacodynamic (PK/PD) Modeling and Simulation by Hinojal Zazo, Yuridia Aguazul, José M. Lanao

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Endoperoxide antimalarials: development, structural diversity and pharmacodynamic aspects with reference to 1,2,4-trioxane-based structural scaffold by Rudrapal M, Chetia D

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Pharmacodynamics of zoliflodacin plus doxycycline combination therapy against Neisseria gonorrhoeae in a gonococcal hollow-fiber infection model by Susanne Jacobsson, Daniel Golparian, Joakim Oxelbark, Fabian Y. S. Kong, Renata Maria Augusto Da Costa, Francois Franceschi, David Brown, Arnold Louie, George Drusano, Magnus Unemo, Magnus Unemo

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Is a Lower Dose of Rivaroxaban Required for Asians? A Systematic Review of a Population Pharmacokinetics and Pharmacodynamics Analysis of Rivaroxaban by Xiao-Qin Liu, Zi-Ran Li, Chen-Yu Wang, Yue-Ting Chen, Zheng Jiao

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Evaluation of Tolerability, Pharmacokinetics and Pharmacodynamics of Vicagrel, a Novel P2Y12 Antagonist, in Healthy Chinese Volunteers by Xiaojiao Li, Cai Liu, Xiaoxue Zhu, Haijing Wei, Hong Zhang, Hong Chen, Guiling Chen, Deming Yang, Hongbin Sun, Zhenwei Shen, Yifan Zhang, Wei Li, Jin Yang, Yongqiang Liu, Xiaojuan Lai, Yanchun Gong, Xuefang Liu, Yongguo Li, Dafang Zhong, Junqi Niu, Bin Liu, Yanhua Ding

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Bacterial Mixology: Combining Pharmacodynamic Models to Predict In Vitro Competition of MCR-1-Harboring <i>E. coli</i> by Nicholas M. Smith, Arthur Chan, Thomas D. Nguyen, Jacob T. Dumbleton

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Integration of Metabolomics With Pharmacodynamics to Elucidate the Anti-myocardial Ischemia Effects of Combination of Notoginseng Total Saponins and Safflower Total Flavonoids by Yuqing Meng, Zhiyong Du, Yan Li, Lichao Wang, Peng Gao, Xiaoyan Gao, Chun Li, Mingbo Zhao, Yong Jiang, Pengfei Tu, Xiaoyu Guo

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Randomized evaluation of the loss‐of‐function carboxylesterase 1 (CES1) G143E variant on clopidogrel and ticagrelor pharmacodynamics by Joshua P. Lewis, Kathleen A. Ryan, Elizabeth A. Streeten, Hilary B. Whitlatch, Melanie Daue, Keith Tanner, James A. Perry, Jeffrey R. O'Connell, Alan R. Shuldiner, Braxton D. Mitchell

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Leishmania blood parasite dynamics during and after treatment of visceral leishmaniasis in Eastern Africa: A pharmacokinetic-pharmacodynamic model. by Luka Verrest, Séverine Monnerat, Ahmed M Musa, Jane Mbui, Eltahir A G Khalil, Joseph Olobo, Monique Wasunna, Wan-Yu Chu, Alwin D R Huitema, Henk D F H Schallig, Fabiana Alves, Thomas P C Dorlo

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Pharmacokinetic/pharmacodynamic modeling for dose selection for the first‐in‐human trial of the activated Factor XII inhibitor garadacimab (CSL312) by Dipti Pawaskar, Xi Chen, Fiona Glassman, Frauke May, Anthony Roberts, Mark Biondo, Andrew McKenzie, Marc W. Nolte, William J. Jusko, Michael Tortorici

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Precision Dosing of Doxapram in Preterm Infants Using Continuous Pharmacodynamic Data and Model-Based Pharmacokinetics: An Illustrative Case Series by Jarinda A. Poppe, Willem van Weteringen, Willem van Weteringen, Lotte L. G. Sebek, Catherijne A. J. Knibbe, Catherijne A. J. Knibbe, Catherijne A. J. Knibbe, Irwin K. M. Reiss, Sinno H. P. Simons, Robert B. Flint, Robert B. Flint

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Multiple-dose pharmacokinetics and pharmacodynamics of evogliptin (DA-1229), a novel dipeptidyl peptidase IV inhibitor, in healthy volunteers by Gu N, Park MK, Kim TE, Bahng MY, Lim KS, Cho SH, Yoon SH, Cho JY, Jang IJ, Yu KS

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Pharmacokinetics/pharmacodynamics of L‐ornithine phenylacetate in overt hepatic encephalopathy and the effect of plasma ammonia concentration reduction on clinical outcomes by Rifaat Safadi, Robert S. Rahimi, Dominique Thabut, Jasmohan S. Bajaj, Kalyan Ram Bhamidimarri, Nikolaos Pyrsopoulos, Amy Potthoff, Stan Bukofzer, Laurene Wang, Khurram Jamil, Krishna R. Devarakonda

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Pharmacokinetic/Pharmacodynamic Adequacy of Novel β-Lactam/β-Lactamase Inhibitors against Gram-Negative Bacterial in Critically Ill Patients by Ruiying Han, Dan Sun, Sihan Li, Jiaojiao Chen, Mengmeng Teng, Bo Yang, Yalin Dong, Taotao Wang

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Remote monitoring with cardiac implantable electronic device to follow up pharmacodynamic effects of sacubitril/valsartan treatment: A case report by Uğur Önsel Türk, Emin Alioğlu

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Pulmonary Pharmacokinetic and Pharmacodynamic Evaluation of Ampicillin/Sulbactam Regimens for Pneumonia Caused by Various Bacteria, including <i>Acinetobacter baumannii</i> by Tetsushu Onita, Kazuro Ikawa, Noriyuki Ishihara, Hiroki Tamaki, Takahisa Yano, Kohji Naora, Norifumi Morikawa

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A descriptive pharmacokinetic/pharmacodynamic analysis of ceftazidime‐avibactam in a case series of critically ill patients with augmented renal clearance by Ying Xu, Jian Tang, Binbin Yuan, Xuemei Luo, Pei Liang, Ning Liu, Danjiang Dong, Lu Jin, Weihong Ge, Qin Gu

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A Model-Based Pharmacokinetic/Pharmacodynamic Analysis of the Combination of Amoxicillin and Monophosphoryl Lipid A Against <i>S. pneumoniae</i> in Mice by Sebastian Franck, Robin Michelet, Fiordiligie Casilag, Jean-Claude Sirard, Sebastian G. Wicha, Charlotte Kloft

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A first‐in‐human, randomized study of the safety, pharmacokinetics and pharmacodynamics of povetacicept, an enhanced dual BAFF/APRIL antagonist, in healthy adults by Rupert Davies, Stanford L. Peng, Jason Lickliter, Kristi McLendon, Amanda Enstrom, Allison G. Chunyk, Lori Blanchfield, NingXin Wang, Tiffany Blair, Heather M. Thomas, Alina Smith, Stacey R. Dillon

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