Search Results - "pharmacodynamics"

Translational pharmacokinetic‐pharmacodynamic modeling of preclinical and clinical data of the oral MET inhibitor tepotinib to determine the recommended phase II dose by Wenyuan Xiong, Manja Friese‐Hamim, Andreas Johne, Christopher Stroh, Manfred Klevesath, Gerald S. Falchook, David S. Hong, Pascal Girard, Samer El Bawab

Connect to this object online.

Novel Pharmacokinetic/Pharmacodynamic Parameters Quantify the Exposure-Effect Relationship of Levofloxacin against Fluoroquinolone-Resistant <i>Escherichia coli</i> by Johanna Seeger, Sebastian Guenther, Katharina Schaufler, Stefan E. Heiden, Robin Michelet, Charlotte Kloft

Connect to this object online.

Pharmacokinetic Behavior and Pharmacokinetic/Pharmacodynamic Integration of Danofloxacin Following Single or Co-Administration with Meloxicam in Healthy Lambs and Lambs with Respiratory Infections by Mehmet Nihat Ural, Kamil Uney

Connect to this object online.

A clinical evaluation to determine the safety, pharmacokinetics, and pharmacodynamics of an inositol-stabilized arginine silicate dietary supplement in healthy adult males by Kalman DS, Feldman S, Samson A, Krieger DR

Connect to this object online.

A Physiologically Based Pharmacokinetic and Pharmacodynamic Model of the CYP3A4 Substrate Felodipine for Drug-Drug Interaction Modeling by Laura Maria Fuhr, Fatima Zahra Marok, Maximilian Mees, Felix Mahfoud, Dominik Selzer, Thorsten Lehr

Connect to this object online.

A comparative pharmacokinetic and pharmacodynamic study of two novel Cuban PEGylated rHuEPO versus MIRCERA® and ior®EPOCIM by Gledys Reynaldo, Leyanis Rodríguez, Roberto Menéndez, Joaquín Solazábal, Daniel Amaro, María de los A. Becquer, Yamila Colom, Haydee Gil, Juan C. Polo, Gilberto Castañeda, Braulio Jiménez-Vélez, Jorge Duconge, Eduardo M. Fernández-Sánchez

Connect to this object online.

Pharmacokinetics, pharmacodynamics, and tolerability of verinurad, a selective uric acid reabsorption inhibitor, in healthy Japanese and non-Asian male subjects by Hall J, Gillen M, Liu S, Miner JN, Valdez S, Shen Z, Lee C

Connect to this object online.

SHR2285, the first selectively oral FXIa inhibitor in China: Safety, tolerability, pharmacokinetics and pharmacodynamics combined with aspirin, clopidogrel or ticagrelor by Tingting Ma, Yanli Dong, Lei Huang, Yuanxun Yang, Yan Geng, Fei Fei, Pinhao Xie, Yu Zhao, Hui Lin, Zeyu Yang, Yun Jin, Xitong Ju, Runbin Sun, Juan Li

Connect to this object online.

In vitro pharmacokinetics/pharmacodynamics of FL058 (a novel beta-lactamase inhibitor) combined with meropenem against carbapenemase-producing Enterobacterales by Zhiwei Huang, Zhiwei Huang, Xingchen Bian, Xingchen Bian, Yi Li, Jiali Hu, Beining Guo, Xinyi Yang, Yi Jin, Shansong Zheng, Xinmei Wang, Cong Gao, Jing Zhang, Xiaojie Wu

Connect to this object online.

A first‐in‐human study of KMRC011, a potential treatment for acute radiation syndrome, to explore tolerability, pharmacokinetics, and pharmacodynamics by Eunsol Yang, Hyejung Choi, Jin‐Sol Park, Young‐Woock Noh, Chi‐Min Choi, Woo‐Jong Lee, Jae‐Wook Ko, Jungryul Kim

Connect to this object online.

Keverprazan, a novel potassium‐competitive acid blocker: Multiple oral doses safety, tolerability, pharmacokinetics, and pharmacodynamics in healthy subjects by Sufeng Zhou, Lijun Xie, Chen Zhou, Lu Wang, Juan Chen, Sijia Ding, Bei Zhu, Mei Su, Feng Shao

Connect to this object online.

Skipping a pillar does not make for strong foundations: Pharmacokinetic‐pharmacodynamic reasoning behind the shape of dose-response relationships in oncology by James W. T. Yates, Hitesh B. Mistry

Connect to this object online.

Target‐Mediated Drug Disposition Pharmacokinetic/Pharmacodynamic Model‐Informed Dose Selection for the First‐in‐Human Study of AVB‐S6‐500 by Laura Bonifacio, Michael Dodds, David Prohaska, Aaron Moss, Amato Giaccia, Ray Tabibiazar, Gail McIntyre

Connect to this object online.

Population Pharmacodynamic Modeling of Epoetin Alfa in End‐Stage Renal Disease Patients Receiving Maintenance Treatment Using Bayesian Approach by Ly Minh Nguyen, Calvin J. Meaney, Gauri G. Rao, Mandip Panesar, Wojciech Krzyzanski

Connect to this object online.

An Industrial Procedure for Pharmacodynamic Improvement of Metformin HCl via Granulation with Its Paracellular Pathway Enhancer Using Factorial Experimental Design by Mady OY, Al-Shoubki AA, Donia AA

Connect to this object online.

Semimechanistic Pharmacodynamic Modeling of Aztreonam‐Avibactam Combination to Understand Its Antimicrobial Activity Against Multidrug‐Resistant Gram‐Negative Bacteria by Alexia Chauzy, Bruna Gaelzer Silva Torres, Julien Buyck, Boudewijn deJonge, Christophe Adier, Sandrine Marchand, William Couet, Nicolas Grégoire

Connect to this object online.

Changes in Pharmacokinetics and Pharmacodynamics of Losartan in Experimental Diseased Rats Treated with <i>Curcuma longa</i> and <i>Lepidium sativum</i> by Abdul Ahad, Mohammad Raish, Ibrahim Abdelsalam Abdelrahman, Yousef A. Bin Jardan, Mohd Aftab Alam, Abdullah M. Al-Mohizea, Fahad I. Al-Jenoobi

Connect to this object online.

Exploratory window‐of‐opportunity trial to investigate the tumor pharmacokinetics/pharmacodynamics of the IAP antagonist Debio 1143 in patients with head and neck cancer by Carlos Gomez‐Roca, Caroline Even, Christophe Le Tourneau, Neus Basté, Jean‐Pierre Delord, Jerome Sarini, Sebastien Vergez, Stephane Temam, Caroline Hoffmann, Philippe Rochaix, Edith Borcoman, Bruno Gavillet, Elisabeth Rouits, Annick Ménétrey, Franck Brichory, Daniela Purcea, Gregoire Vuagniaux, Claudio Zanna

Connect to this object online.

Return to ovulation after Sayana Press is injected every 4 months for one year: Empirical and pharmacokinetic/pharmacodynamic modeling results by Douglas J. Taylor, Jennifer Deese, Luis Bahamondes, Vivian Brache, Nelio Veiga, Jr, Rachael Fuchs, Vera Halpern, Laneta J. Dorflinger

Connect to this object online.

A Network Pharmacology-Based Investigation to the Pharmacodynamic Material Basis and Mechanisms of the Anti-Inflammatory and Anti-Viral Effect of Isatis indigotica by Deng J, Ma Y, He Y, Yang H, Chen Y, Wang L, Huang D, Qiu S, Tao X, Chen W

Connect to this object online.