Search Results - "pharmacodynamics"

Evaluation of Piperacillin/Sulbactam, Piperacillin/Tazobactam and Cefoperazone/Sulbactam Dosages in Gram-Negative Bacterial Bloodstream Infections by Monte Carlo Simulation by Xueting Wang, Luying Xiong, Wei Yu, Chen Huang, Jinru Ji, Chaoqun Ying, Zhiying Liu, Yunbo Chen, Yonghong Xiao

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Effects of Hydroxylated Mephedrone Metabolites on Monoamine Transporter Activity in vitro by Marco Niello, Daniela Cintulová, Philip Raithmayr, Marion Holy, Kathrin Jäntsch, Claire Colas, Gerhard F. Ecker, Harald H. Sitte, Marko D. Mihovilovic

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Applications of linking PBPK and PD models to predict the impact of genotypic variability, formulation differences, differences in target binding capacity and target site drug conc... by Manoranjenni eChetty, Rachel eRose, Khaled eAbduljalil, Nikunjkumar ePatel, Gaohua eLu, Theresa eCain, Masoud eJamei, Amin eRostami-Hodjegan, Amin eRostami-Hodjegan

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Intestinally-restricted Janus Kinase inhibition: a potential approach to maximize the therapeutic index in inflammatory bowel disease therapy by David T. Beattie, M. Teresa Pulido-Rios, Fei Shen, Melissa Ho, Eva Situ, Pam R. Tsuruda, Patrick Brassil, Melanie Kleinschek, Sharath Hegde

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Cannabinoids and Pain: New Insights From Old Molecules by Sonja Vučković, Dragana Srebro, Katarina Savić Vujović, Čedomir Vučetić, Čedomir Vučetić, Milica Prostran

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Application of bioactivity validation as quality control approach: Panax notoginseng dominated scientific-driven new TCM formulae-BPAid from laboratory to industrial scale by Wan Yin Tew, Yean Chun Loh, Chong Seng Yan, Hui Wei Loh, Chen Jingying, Chen Ying, Lee Suan Chua, Guo Longgang, Xu Wen, Xu Wei, Mun Fei Yam

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Scope and relevance of a pulmonary biopharmaceutical classification system AAPS/FDA/USP Workshop March 16-17th, 2015 in Baltimore, MD by Jayne E. Hastedt, Per Bäckman, Andrew R. Clark, William Doub, Anthony Hickey, Guenther Hochhaus, Phil J. Kuehl, Claus-Michael Lehr, Peter Mauser, Jason McConville, Ralph Niven, Masahiro Sakagimi, Jeffry G. Weers

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Pharmacokinetics of Intraperitoneal Vancomycin and Amikacin in Automated Peritoneal Dialysis Patients With Peritonitis by Pâmela Falbo dos Reis, Pasqual Barretti, Laudilene Marinho, Andre Luís Balbi, Linda Awdishu, Daniela Ponce

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Genetic polymorphisms influencing deferasirox pharmacokinetics, efficacy, and adverse drug reactions: a systematic review and meta-analysis by Kittika Yampayon, Puree Anantachoti, Bunchai Chongmelaxme, Varalee Yodsurang, Varalee Yodsurang

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The Effects of Personal Pharmacogenetic Testing on the Effects of Pharmacy Student Perceptions of Knowledge and Attitudes Towards Precision Medicine by Dalga D Surofchy, PharmD (c), Sam Oh, PhD, MPH, Joshua Galanter, MD, MAS, Pin Xiang, PharmD, Megan Li, PhD (c), Su Guo, PhD, Tejal Desai, PhD, B Joseph Guglielmo, PharmD, Kathy Giacomini, PhD, Janel Long-Boyle, PharmD, PhD, Alan HB Wu, PhD, Esteban Burchard, MD, MPH

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Effect of CSL112 (apolipoprotein A‐I [human]) on cholesterol efflux capacity in Japanese subjects: Findings from a phase I study and a cross‐study comparison by Bo Zheng, Shinya Goto, Regina Clementi, John Feaster, Danielle Duffy, Penelope Dalitz, Jolanta Airey, Serge Korjian, Michael A. Tortorici, John Roberts, C. Michael Gibson

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A Phase I, Randomized, Double‐Blind, Placebo‐Controlled, Single‐Dose and Multiple‐Rising‐Dose Study of the BTK Inhibitor TAK‐020 in Healthy Subjects by Ehsanollah Esfandiari, Mary Chen, Glennda Smithson, Derek Blair, Helene Faessel, John Wagner, Lachy Mclean, Eric R. Fedyk

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Dose‐dependent inactivation of airway tryptase with a novel dissociating anti‐tryptase antibody (MTPS9579A) in healthy participants: A randomized trial by Sharon M. Rymut, Siddharth Sukumaran, Gizette Sperinde, Meire Bremer, Joshua Galanter, Kenta Yoshida, Jordan Smith, Prajna Banerjee, Viyia Sverkos, Fang Cai, Verena Steffen, Lindsay M. Henderson, Horace Rhee, Paula N. Belloni, Joseph H. Lin, Tracy L. Staton

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GENDER CHARACTERISTICS OF ADVERSE DRUG REACTIONS DEVELOPMENT: EXPERIENCE OF REGIONAL DATABASE ANALYSIS by A. V. Matveev, A. E. Krasheninnikov, E. A. Egorova, E. I. Konyaeva, N. V. Matveeva

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Phage Therapy: Past; Present and Future by Stephen T. Abedon

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Molecular Pathways and Roles for Vitamin K2-7 as a Health-Beneficial Nutraceutical: Challenges and Opportunities by Nikita Jadhav, Saiprasad Ajgaonkar, Praful Saha, Pranay Gurav, Amitkumar Pandey, Vivek Basudkar, Yash Gada, Sangita Panda, Shashank Jadhav, Dilip Mehta, Sujit Nair

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A Randomized, Open-Label, Phase I, Single-Dose Study of Antisense Oligonucleotide, Vupanorsen, in Chinese Adults with Elevated Triglycerides by Xiaojie Wu, Jicheng Yu, Beikang Ge, Jeffrey Wang, Xiaoran Han, Chunye Zhang, Xiaomeng Mao, Hindu Kalluru, Candace Bramson, Steven G. Terra, Jing Liu

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Measuring Near-Infrared Spectroscopy Derived Cerebral Autoregulation in Neonates: From Research Tool Toward Bedside Multimodal Monitoring by Liesbeth Thewissen, Liesbeth Thewissen, Alexander Caicedo, Alexander Caicedo, Petra Lemmers, Frank Van Bel, Sabine Van Huffel, Sabine Van Huffel, Gunnar Naulaers, Gunnar Naulaers

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Machine Learning and Pharmacometrics for Prediction of Pharmacokinetic Data: Differences, Similarities and Challenges Illustrated with Rifampicin by Lina Keutzer, Huifang You, Ali Farnoud, Joakim Nyberg, Sebastian G. Wicha, Gareth Maher-Edwards, Georgios Vlasakakis, Gita Khalili Moghaddam, Elin M. Svensson, Michael P. Menden, Ulrika S. H. Simonsson, on behalf of the UNITE4TB Consortium

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First‐in‐human study of JNJ‐67571244, a CD33 × CD3 bispecific antibody, in relapsed/refractory acute myeloid leukemia and myelodysplastic syndrome by Rupa Narayan, Ana Alfonso Piérola, William B. Donnellan, Antonieta Molero Yordi, Maher Abdul‐Hay, Uwe Platzbecker, Marion Subklewe, Tapan Mahendra Kadia, Juan Manuel Alonso‐Domínguez, James McCloskey, Kathryn Bradford, Martin Curtis, Nikki Daskalakis, Christina Guttke, Karim Safer, Brett Hiebert, Joseph Murphy, Xiang Li, Ken Duchin, Daniel Esteban

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