Search Results - "pharmacodynamics"

Loading regimen required to rapidly achieve therapeutic trough plasma concentration of teicoplanin and evaluation of clinical features by Seki M, Yabuno K, Miyawaki K, Miwa Y, Tomono K

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A phase I, randomized, ascending‐dose study to assess safety, pharmacokinetics, and activity of GDC‐8264, a RIP1 inhibitor, in healthy volunteers by Nicholas S. Jones, Smita Kshirsagar, Vishnu Mohanan, Vidya Ramakrishnan, Flavia Di Nucci, Ling Ma, Jialin Mao, Hao Ding, Sha Klabunde, Domagoj Vucic, Lin Pan, Annemarie N. Lekkerkerker, Yuan Chen, Michael E. Rothenberg

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Computational approach towards the design of artemisinin-thymoquinone hybrids against main protease of SARS-COV-2 by Victor Moreira de Oliveira, Matheus Nunes da Rocha, Emanuel Paula Magalhães, Francisco Rogênio da Silva Mendes, Márcia Machado Marinho, Ramon Róseo Paula Pessoa Bezerra de Menezes, Tiago Lima Sampaio, Hélcio Silva dos Santos, Alice Maria Costa Martins, Emmanuel Silva Marinho

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Adverse Drug Reactions of Acetylcholinesterase Inhibitors in Older People Living with Dementia: A Comprehensive Literature Review by Ruangritchankul S, Chantharit P, Srisuma S, Gray LC

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Pharmacometric Analysis of Intranasal and Intravenous Nalbuphine to Optimize Pain Management in Infants by Miriam Pfiffner, Eva Berger-Olah, Priska Vonbach, Priska Vonbach, Marc Pfister, Verena Gotta

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SDI-118, a novel procognitive SV2A modulator: First-in-human randomized controlled trial including PET/fMRI assessment of target engagement by Wouter Botermans, Michel Koole, Koen Van Laere, Jonathan R. Savidge, John A. Kemp, Stefan Sunaert, Maeve M. Duffy, Steven Ramael, Andrea M. Cesura, Kevin D'Ostilio, Denis Gossen, Torsten M. Madsen, Thomas Lodeweyckx, Jan de Hoon

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Magnesium sulfate pharmacokinetics after intramuscular dosing in women with preeclampsiaAJOG Global Reports at a Glance by Kathleen Brookfield, MD, PhD, MPH, Hadiza Galadanci, MBBS, MSc, Lihong Du, PhD, Larissa Wenning, PhD, Idris Mohammed, MBBS, MSc, Maryam Suleiman, MBBS, Olufemi T. Oladapo, MD, MPH, Han Witjes, PhD, Brendan Carvalho, MBBCh

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An Integrated Pharmacology-Based Strategy to Investigate the Potential Mechanism of Xiebai San in Treating Pediatric Pneumonia by Zhuohui Luo, Zhuohui Luo, Jiawen Huang, Ennian Li, Xinqian He, Qiqi Meng, Xinan Huang, Xiaoling Shen, Changkai Yan

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Bibliometric Analysis of Global Trends in Remimazolam-Related Research Over the Past 15 Years: Compared with Propofol by Hu X, Wang B, Hu L, Han D, Wu J

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Pharmacokinetics of Enrofloxacin in Plasma, Urine, and Feces of Donkey (<i>Equus asinus</i>) after a Single Intragastric Administration by Bowen Yang, Shijie Liu, Jie Cheng, Honglei Qu, Yanxin Guo, Chuanliang Ji, Yantao Wang, Shancang Zhao, Shimeng Huang, Lihong Zhao, Qiugang Ma

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Clearing the smokescreen: The current evidence on cannabis use by Margriet van Laar

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Regional Intestinal Drug Absorption Biopharmaceutics and Drug Formulation

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Association Study Among Candidate Genetic Polymorphisms and Chemotherapy-Related Severe Toxicity in Testicular Cancer Patients by María A. Lavanderos, Juan P. Cayún, Ángela Roco, Ángela Roco, Christopher Sandoval, Leslie Cerpa, Juan C. Rubilar, Roberto Cerro, Sebastián Molina-Mellico, Cesar Celedón, Berta Cerda, Elena García-Martín, José A. G. Agúndez, Cristián Acevedo, Cristián Acevedo, Karina Peña, Dante D. Cáceres, Dante D. Cáceres, Nelson M. Varela, Luis A. Quiñones

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Tracking disease progression non‐invasively in Duchenne and Becker muscular dystrophies by Pietro Spitali, Kristina Hettne, Roula Tsonaka, Mohammed Charrout, Janneke van denBergen, Zaïda Koeks, Hermien E. Kan, Melissa T. Hooijmans, Andreas Roos, Volker Straub, Francesco Muntoni, Cristina Al‐Khalili‐Szigyarto, Marleen J.A. Koel‐Simmelink, Charlotte E. Teunissen, Hanns Lochmüller, Erik H. Niks, Annemieke Aartsma‐Rus

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Hepatic Cytochrome P450 Abundance and Activity in the Developing and Adult Göttingen Minipig: Pivotal Data for PBPK Modeling by Laura Buyssens, Laura De Clerck, Wim Schelstraete, Maarten Dhaenens, Dieter Deforce, Miriam Ayuso, Chris Van Ginneken, Steven Van Cruchten

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A prospective, observational study comparing the PK/PD relationships of generic Meropenem (Mercide&reg;) to the innovator brand in critically ill patients by Mer M, Snyman JR, van Rensburg CEJ, van Tonder JJ, Laurens I

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Rejuveinix Shows a Favorable Clinical Safety Profile in Human Subjects and Exhibits Potent Preclinical Protective Activity in the Lipopolysaccharide-Galactosamine Mouse Model of Ac... by Fatih M. Uckun, Fatih M. Uckun, James Carlson, Cemal Orhan, Joy Powell, Natalie M. Pizzimenti, Hendrik van Wyk, Ibrahim H. Ozercan, Michael Volk, Kazim Sahin

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Effect of Different Piperacillin-Tazobactam Dosage Regimens on Synergy of the Combination with Tobramycin against <i>Pseudomonas aeruginosa</i> for the Pharmacokinetics of Critical... by Jessica R. Tait, Hajira Bilal, Kate E. Rogers, Yinzhi Lang, Tae-Hwan Kim, Jieqiang Zhou, Steven C. Wallis, Jürgen B. Bulitta, Carl M. J. Kirkpatrick, David L. Paterson, Jeffrey Lipman, Phillip J. Bergen, Jason A. Roberts, Roger L. Nation, Cornelia B. Landersdorfer

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Model Informed Dosing Regimen and Phase I Results of the Anti‐PD‐1 Antibody Budigalimab (ABBV‐181) by John Powderly, Alexander Spira, Shunsuke Kondo, Toshihiko Doi, Jason J. Luke, Drew Rasco, Bo Gao, Minna Tanner, Philippe A. Cassier, Anas Gazzah, Antoine Italiano, Diego Tosi, Daniel E. Afar, Apurvasena Parikh, Benjamin Engelhardt, Stefan Englert, Stacie L. Lambert, Sreeneeranj Kasichayanula, Sven Mensing, Rajeev Menon, Gregory Vosganian, Anthony Tolcher

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In silico study of properties in the series of 1-alkyl-4-(((5-nitrofuran-2-yl)methylene)amino)- 1,2,4-triazole halides by L. I. Kucherenko, T. S. Brytanova, A. S. Hotsulia

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