Search Results - "pharmacogenetics"

Parkinson's Disease Understanding Pathophysiology and Developing Therapeutic Strategies

Subjects: “…parkinson's disease, tissue engineering, regenerative medicine, personalized medicine, phenotype, pharmacogenetics…”
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Optimizing clopidogrel dose response: a new clinical algorithm comprising CYP2C19 pharmacogenetics and drug interactions by Saab YB, Zeenny R, Ramadan WH

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Molecular identification of HLA‐B75 serotype markers by qPCR: A more inclusive pharmacogenetic approach before carbamazepine prescription by Kanoot Jaruthamsophon, Pornsiri Sangmanee, Oradawan Plong‐on, Chariyawan Charalsawadi, Chonlaphat Sukasem, Areerat Hnoonual

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Healthcare Professionals' Knowledge of Pharmacogenetics and Attitudes Towards Antimicrobial Utilization in Zambia: Implications for a Precision Medicine Approach to Reducing Antimicrobial Resistance by Webrod Mufwambi, Webrod Mufwambi, Webrod Mufwambi, Julia Stingl, Collen Masimirembwa, Justen Manasa, Justen Manasa, Charles Nhachi, Nadina Stadler, Chiluba Mwila, Aubrey Chichonyi Kalungia, Moses Mukosha, Chenai S. Mutiti, Chenai S. Mutiti, Alfred Kamoto, Alfred Kamoto, Patrick Kaonga, Patrick Kaonga, Brian Godman, Brian Godman, Brian Godman, Derick Munkombwe

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Editorial: Pharmacogenetics and pharmacogenomics in Latin America: ethnic variability, new insights in advances and perspectives: a RELIVAF-CYTED initiative, Volume II by Andrés López-Cortés, Andrés López-Cortés, Patricia Esperón, Patricia Esperón, Matías F. Martínez, Matías F. Martínez, Matías F. Martínez, María A. Redal, María A. Redal, María A. Redal, Alberto Lazarowski, Alberto Lazarowski, Nelson M. Varela, Nelson M. Varela, Ismael Lares-Asseff, Ismael Lares-Asseff, Luis A. Quiñones, Luis A. Quiñones, Luis A. Quiñones

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Development and Analytical Validation of a 29 Gene Clinical Pharmacogenetic Genotyping Panel: Multi‐Ethnic Allele and Copy Number Variant Detection by Stuart A. Scott, Erick R. Scott, Yoshinori Seki, Annette J. Chen, Richard Wallsten, Aniwaa Owusu Obeng, Mariana R. Botton, Neal Cody, Huanzhi Shi, Geping Zhao, Paul Brake, Paola Nicoletti, Yao Yang, Maria Delio, Lisong Shi, Ruth Kornreich, Eric E. Schadt, Lisa Edelmann

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The Influence of Pharmacogenetics on the Clinical Relevance of Pharmacokinetic Drug-Drug Interactions: Drug-Gene, Drug-Gene-Gene and Drug-Drug-Gene Interactions by Martina Hahn, Sibylle C. Roll

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Associations of CYP2C9 and CYP2C19 Pharmacogenetic Variation with Phenytoin‐Induced Cutaneous Adverse Drug Reactions by Alison E. Fohner, Allan E. Rettie, Khanh K. Thai, Dilrini K. Ranatunga, Brian L. Lawson, Vincent X. Liu, Catherine A. Schaefer

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Review of the Reported Measures of Clinical Validity and Clinical Utility as Arguments for the Implementation of Pharmacogenetic Testing: A Case Study of Statin-Induced Muscle Toxicity by Marleen E. Jansen, Marleen E. Jansen, T. Rigter, T. Rigter, W. Rodenburg, T. M. C. Fleur, T. M. C. Fleur, E. J. F. Houwink, M. Weda, Martina C. Cornel

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Pharmacogenetic variants of CYP2C9 and CYP2C19 associated with adverse reactions induced by antiepileptic drugs used in Peru by Angel T. Alvarado, Ana María Muñoz, Nelson Varela, Luis Sullón-Dextre, Mario Pineda, Mario Bolarte-Arteaga, María R. Bendezú, Jorge A. García, Haydee Chávez, Felipe Surco-Laos, Elizabeth J. Melgar-Merino, Pompeyo A. Cuba-Garcia, Aura Molina-Cabrera, Bertha Pari-Olarte, Mario Bonifaz-Hernandez, Juan F. Panay-Centeno, José Kong-Chirinos, José Almeida-Galindo

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An exploratory analysis of associations of genetic variation with the efficacy of tocilizumab in severe COVID-19 patients. A pharmacogenetic study based on next-generation sequencing by Alejandro Durán-Sotuela, Jorge Vázquez-García, Sara Relaño-Fernández, Vanesa Balboa-Barreiro, Juan Fernández-Tajes, Francisco J. Blanco, Francisco J. Blanco, Ignacio Rego-Pérez

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Pharmacogenetics-based population pharmacokinetic analysis and dose optimization of valproic acid in Chinese southern children with epilepsy: Effect of ABCB1 gene polymorphism by Xianhuan Shen, Xianhuan Shen, Xinyi Chen, Jieluan Lu, Jieluan Lu, Qing Chen, Wenzhou Li, Jiahao Zhu, Jiahao Zhu, Yaodong He, Yaodong He, Huijuan Guo, Chenshu Xu, Xiaomei Fan

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Genetic polymorphisms of CYP3A5, CHRM2, and ZNF498 and their association with epilepsy susceptibility: a pharmacogenetic and case–control study by AL-Eitan LN, Al-Dalalah IM, Mustafa MM, Alghamdi MA, Elshammari AK, Khreisat WH, Al-Quasmi MN, Aljamal HA

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108 Actionable pharmacogenetic variants in hong kong chinese exome data and projected prescription impact in the hong kong population leading to precision medicine by Kit San Yeung, Brian Chung, Mullin Yu, Marcus Chan, Clara Tang, Claudia Chung

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Exploring Variability in Rifampicin Plasma Exposure and Development of Anti-Tuberculosis Drug-Induced Liver Injury among Patients with Pulmonary Tuberculosis from the Pharmacogenetic Perspective by Agnija Kivrane, Viktorija Ulanova, Solveiga Grinberga, Eduards Sevostjanovs, Anda Viksna, Iveta Ozere, Ineta Bogdanova, Maksims Zolovs, Renate Ranka

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An Interdisciplinary Experience focused on Pharmacogenetics: Engaging pharmacy and physician assistant students in conversations about antiplatelet therapy with respect to CYP2C19 genotype by Diane M Calinski, David F Kisor

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Toward pharmacogenetic SLCO1B1‐guided dosing of methotrexate in arthritis using a murine Slco1b2 knockout model by Zachary L. Taylor, Lauren E. Thompson, Heather Bear, Tomoyuki Mizuno, Alexander A. Vinks, Laura B. Ramsey

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Clinical Pharmacogenetic Models of Treatment Response to Methotrexate Monotherapy in Slovenian and Serbian Rheumatoid Arthritis Patients: Differences in Patient's Management May Preclude Generalization of the Models by Barbara Jenko, Matija Tomšič, Matija Tomšič, Biljana Jekić, Vera Milić, Vita Dolžan, Sonja Praprotnik, Sonja Praprotnik

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Case report: Use of therapeutic drug monitoring and pharmacogenetic testing as opportunities to individualize care in a case of flecainide toxicity after fetal supraventricular tachycardia by Ronald Palmen, Ronald Palmen, Ronald Palmen, Tracy Sandritter, Tracy Sandritter, Lindsey Malloy-Walton, Lindsey Malloy-Walton, Lindsey Malloy-Walton, Christopher Follansbee, Christopher Follansbee, Christopher Follansbee, Jonathan B. Wagner, Jonathan B. Wagner, Jonathan B. Wagner, Jonathan B. Wagner, Jonathan B. Wagner

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Nephrotoxicity in a Patient With Inadequate Pain Control: Potential Role of Pharmacogenetic Testing for Cytochrome P450 2D6 and Apolipoprotein L1 by Emma M. Tillman, Todd C. Skaar, Michael T. Eadon

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