Search Results - "pharmacokinetics"

Safety, tolerability, and pharmacokinetics of TG-1000, a new molecular entity against influenza virus: first-in-human study by Su-Mei Xu, Su-Mei Xu, Li-Wen Chang, Cheng-Yuan Tsai, Wan-Li Liu, Wan-Li Liu, Dai Li, Dai Li, Shan-Shan Li, Shan-Shan Li, Xiao-Min Li, Xiao-Min Li, Ping-Sheng Xu, Ping-Sheng Xu

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Nanocrystal Formulation to Enhance Oral Absorption of Silybin: Preparation, In Vitro Evaluations, and Pharmacokinetic Evaluations in Rats and Healthy Human Subjects by SeungRee Seo, Gwan-Young Kim, Min-Hwan Kim, Kyung Won Lee, Min-Jae Kim, Mansingh Chaudhary, Khadka Bikram, Taeheon Kim, Seungmok Choi, Heejin Yang, Joo Won Park, Dae-Duk Kim, Ki-Taek Kim

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Development and application of a simple physiologically based pharmacokinetic model that quantitatively describes the distribution and elimination of the commonly measured proteins by David G. Levitt, Michael D. Levitt

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Pharmacokinetics and Anti-asthmatic Potential of Non-parenterally Administered Recombinant Human Interleukin-1 Receptor Antagonist in Animal Models by Ting Li, Wan-Liang Lu, Hai-Yan Hong, Yan-Sheng Yao, Pu Han, Zhong-Kun Li, Gui-Ling Wang, Yi Cao, Xiang-Rui Liu, Jian-Cheng Wang, Xuan Zhang, Qiang Zhang

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Simultaneous determination of indapamide, perindopril and perindoprilat in human plasma or whole blood by UPLC-MS/MS and its pharmacokinetic application by Yi Tao, Sheng Wang, Lei Wang, Min Song, Taijun Hang

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Development of a UPLCâMS/MS method for determination of pimavanserin tartrate in rat plasma: Application to a pharmacokinetic study by Shixiao Wang, Yang Wang, Shuang Gao, Yuanyuan Zhang, Hanpei Wang, Longshan Zhao, Kaishun Bi, Shaojie Wang, Xiaohui Chen

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Pharmacokinetic‐pharmacodynamic model of urinary δ‐aminolevulinic acid reduction after givosiran treatment in patients with acute hepatic porphyria by Jongtae Lee, Megan Melch, Gabriel J. Robbie

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A Mechanistic, Enantioselective, Physiologically Based Pharmacokinetic Model of Verapamil and Norverapamil, Built and Evaluated for Drug-Drug Interaction Studies by Nina Hanke, Denise Türk, Dominik Selzer, Sabrina Wiebe, Éric Fernandez, Peter Stopfer, Valerie Nock, Thorsten Lehr

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Phase I studies of the safety, tolerability, pharmacokinetics, and pharmacodynamics of DS‐1211, a tissue‐nonspecific alkaline phosphatase inhibitor by Sonomi Maruyama, Hester Visser, Takashi Ito, Tharin Limsakun, Hamim Zahir, Daniel Ford, Ben Tao, Cynthia A. Zamora, Jeffrey G. Stark, Hubert S. Chou

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Pharmacokinetics of Repeated Oral Dosing with Coenzyme Q10 in Cavalier King Charles Spaniels with Myxomatous Mitral Valve Disease by Liselotte B. Christiansen, Malene K. Morsing, Maria Josefine Reimann, Torben Martinussen, Zita Birlie, Anne Marie V. Schou-Pedersen, Jens Lykkesfeldt, Lisbeth H. Olsen

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ABCG2 Single Nucleotide Polymorphism Affects Imatinib Pharmacokinetics in Lower Alpha-1-Acid Glycoprotein Levels in Humans by Jin-Woo Park, Hyewon Chung, Kyoung-Ah Kim, Jong-Min Kim, In-Hwan Park, Sangjin Lee, Ji-Young Park

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A simple LC-MS/MS method for pharmacokinetic study of carvedilol and 4/-hydroxyphenyl carvedilol at a low dose by Wanna Eiamart, Nantaporn Prompila, Yaowatree Jumroen, Nonlanee Sayankuldilok, Pajaree Chariyavilaskul, Supeecha Wittayalertpanya

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Synthesis and appraisal of dalbergin-loaded PLGA nanoparticles modified with galactose against hepatocellular carcinoma: In-vitro, pharmacokinetic, and in-silico studies by Anurag Kumar Gautam, Pranesh Kumar, Pranesh Kumar, Biswanath Maity, Ganesh Routholla, Balaram Ghosh, Kumarappan Chidambaram, M. Yasmin Begum, Adel Al Fatease, P.S. Rajinikanth, Sanjay Singh, Sudipta Saha, Vijayakumar M. R.

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Unveiling the Influence of a High-Fat Meal on the Pharmacokinetics of Oral Globalagliatin, A Glucokinase Activator, in Healthy Chinese Volunteers by Maodi Xu, Yaqin Wang, Xiaohu Wang, Zhichen Pu, Ya Liu, Cuilian Jiang, Xiaokun Shen, Hua Sun, Haitang Xie

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Population pharmacokinetic study of benznidazole in pediatric Chagas disease suggests efficacy despite lower plasma concentrations than in adults. by Jaime Altcheh, Guillermo Moscatelli, Guido Mastrantonio, Samanta Moroni, Norberto Giglio, Maria Elena Marson, Griselda Ballering, Margarita Bisio, Gideon Koren, Facundo García-Bournissen

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Population pharmacokinetic‐pharmacodynamic analyses of amyloid positron emission tomography and plasma biomarkers for lecanemab in subjects with early Alzheimer's disease by Seiichi Hayato, Osamu Takenaka, Sree Harsha Sreerama Reddy, Ishani Landry, Larisa Reyderman, Akihiko Koyama, Chad Swanson, Sanae Yasuda, Ziad Hussein

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Interspecies and in vitro‐in vivo scaling for quantitative modeling of whole‐body drug pharmacokinetics in patients: Application to the anticancer drug oxaliplatin by Simona Catozzi, Roger Hill, Xiao‐Mei Li, Sandrine Dulong, Elodie Collard, Annabelle Ballesta

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Effects of Posaconazole on Tacrolimus Population Pharmacokinetics and Initial Dose in Children With Crohn's Disease Undergoing Hematopoietic Stem Cell Transplantation by Xiao Chen, Dongdong Wang, Feng Zheng, Lin Zhu, Yidie Huang, Yiqing Zhu, Ying Huang, Hong Xu, Zhiping Li

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Adaptation of a human gut epithelial model in relation to the assessment of clinical pharmacokinetic parameters for selected tyrosine kinase inhibitors by Richard Honeywell, Christien Fatmawati, Marita Buddha, Sarina Hitzerd, Ietje Kathman, Godefridus Peters

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Validated DBS method for filgotinib quantitation in rat dried blood spots and its application to a pharmacokinetic study in rats by Abhishek Dixit, Vinay Kiran, Bhavesh Babulal Gabani, Ramesh Mullangi

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