Search Results - "pharmacokinetics"

Similar Piperacillin/Tazobactam Target Attainment in Obese versus Nonobese Patients despite Differences in Interstitial Tissue Fluid Pharmacokinetics by David Busse, Philipp Simon, David Petroff, Christoph Dorn, Lisa Schmitt, Davide Bindellini, Alexander Kratzer, Arne Dietrich, Markus Zeitlinger, Wilhelm Huisinga, Robin Michelet, Hermann Wrigge, Charlotte Kloft

Connect to this object online.

Simultaneous determination of telmisartan and amlodipine in human plasma by LCâMS/MS and its application in a human pharmacokinetic study by Vasu Babu Ravi, Jaswanth Kumar Inamadugu, Nageswara Rao Pilli, Vudagandla Sreenivasulu, Venkateswarlu Ponneri

Connect to this object online.

First‐in‐human study evaluating safety, pharmacokinetics, and pharmacodynamics of lorundrostat, a novel and highly selective aldosterone synthase inhibitor by Hidetoshi Shimizu, Michael A. Tortorici, Yoshiyasu Ohta, Kei Ogawa, Sheikh Mohammed Ashfaq Rahman, Aya Fujii, Yuki Hiraga, Mizue Kawai, Kanami Sugimoto‐Kawabata, Mattheus (Thijs), Jan Jaap vanLier, Stephen Djedjos, B. T. Slingsby, David M. Rodman

Connect to this object online.

Relationship between Pharmacokinetic Profile and Clinical Efficacy Data of Three Different Forms of Locally Applied Flurbiprofen in the Mouth/Throat by Vit Perlik, Anuradha Kulasekaran, Graça Coutinho, Martin Votava, Jean-Michel Cardot

Connect to this object online.

Influence of pretreatment of piperazine ferulate on pharmacokinetic parameters of methotrexate in methotrexate-induced renal injury model rats by HPLC-MS by Huiyan Shi, Chenzhi Hou, Liqiang Gu, Zhe Wei, Hang Xing, Meiyu Zhang, Shixiao Wang, Longshan Zhao, Kaishun Bi, Xiaohui Chen

Connect to this object online.

A phase I study comparing the pharmacokinetics of the biosimilar (RD12014) with liraglutide (Victoza) in healthy Chinese male subjects by Ruirui Zhou, Linfeng Guo, Xianglei Gao, Yijun Wang, Wenjing Xu, Yang Zou, Wenjia Li, Yulei Zhuang, Gangyi Liu, Yanmei Liu

Connect to this object online.

Prediction of Drug-Drug Interactions Between Opioids and Overdosed Benzodiazepines Using Physiologically Based Pharmacokinetic (PBPK) Modeling and Simulation by Beihong Ji, Shuhan Liu, Ying Xue, Xibing He, Viet Hoang Man, Xiang-Qun Xie, Junmei Wang

Connect to this object online.

Pharmacokinetics, pharmacodynamics, and safety of fesomersen, a novel antisense inhibitor of factor XI, in healthy Chinese, Japanese, and Caucasian volunteers by Tianxing Liu, Kensei Hashizume, Eva Krieg, Huijun Chen, Yuki Mukaida, Kirstin Thelen, Frauke Friedrichs, Stefan Willmann, Stephan Schwers, Alexander Solms, Rosie Yu

Connect to this object online.

Phase I evaluation of the safety, tolerability, and pharmacokinetics of GSK3640254, a next‐generation HIV‐1 maturation inhibitor by Samit R. Joshi, Disala Fernando, Stephanie Igwe, Litza McKenzie, Anu S. Krishnatry, Fiona Halliday, Joyce Zhan, Thomas J. Greene, Jianfeng Xu, Geraldine Ferron‐Brady, Max Lataillade, Sherene Min

Connect to this object online.

Evaluation of pharmacokinetics and safety of cetuximab with cisplatin/carboplatin in patients with advanced solid tumor: Result from phase II studies by Raymond P. Perez, Eric Chen, J. Thaddeus Beck, Keisuke Shirai, David Neil Hayes, Tong Shen, John R. Baldwin, Katherine B. Bryant, Shuang He, Steve Chin

Connect to this object online.

Development and validation of liquid chromatography method for determination of glimepiride in presence of (Vimto®) soft drinks in rats: application to pharmacokinetics studies by Mohammed Hamad, Areej Rahhal, Wael Abu Dayyih, Eyad Mallah, Alice Abu Dayyih, Zainab Zakaria, Tawfiq Arafat

Connect to this object online.

Phase I and pharmacokinetic study of the vascular‐disrupting agent CKD‐516 (NOV120401) in patients with refractory solid tumors by Hark Kyun Kim, Jeong Won Kang, Young‐Whan Park, Jung Young Kim, Minchae Kim, Soo Jin Kim, Se‐mi Kim, Keun Ho Ryu, Seonghae Yoon, Yun Kim, Joo‐Youn Cho, Keun Seok Lee, Tak Yun, Kiwon Kim, Mi Hyang Kwak, Tae‐Sung Kim, Jinsoo Chung, Joong‐Won Park

Connect to this object online.

Phase III dose selection of marzeptacog alfa (activated) informed by population pharmacokinetic modeling: A novel hemostatic drug by Alan Faraj, Tom Knudsen, Shraddha Desai, Linda Neuman, Grant E. Blouse, Ulrika S. H. Simonsson

Connect to this object online.

Development of Abiraterone Acetate Nanocrystal Tablets to Enhance Oral Bioavailability: Formulation Optimization, Characterization, In Vitro Dissolution and Pharmacokinetic Evaluation by Yuanfen Liu, Yuqi Li, Pengcheng Xu, Yan Shen, Baoqiang Tang, Qiyue Wang

Connect to this object online.

Evaluation and Application of Population Pharmacokinetic Models for Identifying Delayed Methotrexate Elimination in Patients With Primary Central Nervous System Lymphoma by Junjun Mao, Qing Li, Qing Li, Pei Li, Weiwei Qin, Bobin Chen, Bobin Chen, Mingkang Zhong

Connect to this object online.

A temporo-spatial pharmacometabolomics method to characterize pharmacokinetics and pharmacodynamics in the brain microregions by using ambient mass spectrometry imaging by Dan Liu, Jianpeng Huang, Shanshan Gao, Hongtao Jin, Jiuming He

Connect to this object online.

Leveraging in vitro and pharmacokinetic models to support bench to bedside investigation of XTMAB-16 as a novel pulmonary sarcoidosis treatment by Elliot Offman, Noopur Singh, Mark W. Julian, Landon W. Locke, Landon W. Locke, Sabahattin Bicer, Jonah Mitchell, Thomas Matthews, Kirsten Anderson, Elliott D. Crouser

Connect to this object online.

Characterization, cellular uptake in Caco-2 cells and physiologically based pharmacokinetic modeling of baicalin-loaded solid lipid nanoparticles by Hussein O. Ammar, Rehab N. Shamma, Carol Yousry, Rasha S. Elbatanony, Basma Khater, Amira M. Ghoneim

Connect to this object online.

Prospective Validation and Refinement of a Population Pharmacokinetic Model of Fludarabine in Children and Young Adults Undergoing Hematopoietic Cell Transplantation by Jordan T. Brooks, Belen P. Solans, Ying Lu, Sandhya Kharbanda, Christopher C. Dvorak, Nahal Lalefar, Susie Long, Ashish O. Gupta, Biljana Horn, Jatinder K. Lamba, Liusheng Huang, Beth Apsel-Winger, Ron J. Keizer, Rada Savic, Janel Long-Boyle

Connect to this object online.

A Study on Acetylglutamine Pharmacokinetics in Rat Blood and Brain Based on Liquid Chromatography-Tandem Mass Spectrometry and Microdialysis Technique by Shouchao Xu, Chang Li, Huifen Zhou, Li Yu, Ling Deng, Jiazhen Zhu, Haitong Wan, Yu He

Connect to this object online.