Search Results - "pharmacokinetics"

Application of a Physiologically Based Pharmacokinetic Model to Predict Cefazolin and Cefuroxime Disposition in Obese Pregnant Women Undergoing Caesarean Section by Hanadi H. Alrammaal, Khaled Abduljalil, Victoria Hodgetts Morton, R. Katie Morris, John F. Marriott, Hsu P. Chong, Hannah K. Batchelor

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A Phase 1 Study to Assess the Pharmacokinetics, Food Effect, Safety, and Tolerability of Sepiapterin in Healthy Japanese and Non-Japanese Participants by Lan Gao, Diksha Kaushik, Kimberly Ingalls, Neil Smith, Ronald Kong

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Development of best practices in physiologically based pharmacokinetic modeling to support clinical pharmacology regulatory decision‐making-A workshop summary by Daphney Jean, Kunal Naik, Lauren Milligan, Stephen Hall, Shiew Mei Huang, Nina Isoherranen, Colleen Kuemmel, Paul Seo, Million A. Tegenge, Yaning Wang, Yuching Yang, Xinyuan Zhang, Liang Zhao, Ping Zhao, Jessica Benjamin, Kimberly Bergman, Joseph Grillo, Rajanikanth Madabushi, Fang Wu, Hao Zhu, Issam Zineh

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Return to ovulation after Sayana Press is injected every 4 months for one year: Empirical and pharmacokinetic/pharmacodynamic modeling results by Douglas J. Taylor, Jennifer Deese, Luis Bahamondes, Vivian Brache, Nelio Veiga, Jr, Rachael Fuchs, Vera Halpern, Laneta J. Dorflinger

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Population pharmacokinetic analysis and dosage recommendations for digoxin in Japanese patients with atrial fibrillation and heart failure using real-world data by Toshinori Hirai, Hidefumi Kasai, Miyoko Naganuma, Nobuhisa Hagiwara, Tsuyoshi Shiga

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A Phase I study evaluating the effect of age and weight on the pharmacokinetics of an injectable formulation of diclofenac solubilized with hydroxypropyl-β-cyclodextrin by Goldwater R, Kramer WG, Hamilton DA, Lang E, Wang J, Madden DE, Lacouture PG, Ramaiya A, Carr DB

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Pharmacokinetic comparison of subcutaneously administered CT‐P13 (biosimilar of infliximab) via autoinjector and pre‐filled syringe in healthy participants by Ye Chan Park, Jae Hoon Kim, Sung Hyun Kim, Ju Hyun Lee, Jang Hee Hong, Jin‐Gyu Jung, Jung Sunwoo

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Redox Imbalance and Oxidative DNA Damage During Isoniazid Treatment of HIV-Associated Tuberculosis: A Clinical and Translational Pharmacokinetic Study by Isaac Zentner, Hyun-moon Back, Leonid Kagan, Selvakumar Subbian, Jyothi Nagajyothi, Shashikant Srivastava, Jotam Pasipanodya, Tawanda Gumbo, Gregory P. Bisson, Christopher Vinnard

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Pharmacokinetics and clinical response to single agent rucaparib in a dialysis dependent patient with BRCA associated breast and recurrent ovarian cancer by Justin A. Harold, Stephanie C. Free, William H. Bradley

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Pharmacokinetics, safety and tolerability of L-3-n-butylphthalide tablet after single and multiple oral administrations in healthy Chinese volunteers by Meng Wang, Quan-ying Zhang, Wen-yan Hua, Ming Huang, Wen-jia Zhou, Kun Lou, Yue-ying Peng

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Pharmacokinetic interaction between single and multiple doses of darunavir, in combination with cobicistat or ritonavir, and single-dose dabigatran etexilate in healthy adults by Sandy Van Hemelryck, Erika Van Landuyt, Jay Ariyawansa, Martyn Palmer, Martine J. C. Kothe, Caroline Pollefliet

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Pharmacokinetics and pharmacodynamics of linezolid in plasma/cerebrospinal fluid in patients with cerebral hemorrhage after lateral ventricular drainage by Monte Carlo simulation by Wu X, Tang Y, Zhang X, Wu C, Kong L

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Impact of posaconazole and diltiazem on pharmacokinetics of encorafenib, a BRAF V600 kinase inhibitor for melanoma and colorectal cancer with BRAF mutations by Erik Hahn, Renae Chavira, Lance Wollenberg, Weiwei Tan, Micaela B. Reddy

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Preparation of Aditoprim Injection against <i>Streptococcus suis</i> in Pigs and a Dose Regimen Based on Pharmacokinetic-Pharmacodynamic Modeling by Wei Qu, Mengxiao Dong, Yuanhu Pan, Shuyu Xie, Zonghui Yuan, Lingli Huang

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Comparative Assessment of Distribution Characteristics and Ocular Pharmacokinetics of Norvancomycin Between Continuous Topical Ocular Instillation and Hourly Administration of Eye Drop by Lin W, Zhao L, Huang X, Tan Q, Peng M, Khan MA, Lin D

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Pharmacokinetic interaction of voriconazole and clarithromycin in Pakistani healthy male volunteers: a single dose, randomized, crossover, open-label study by Mehwish Mushtaq, Mehwish Mushtaq, Kshaf Fatima, Aneeqa Ahmad, Osama Mohamed Ibrahim, Osama Mohamed Ibrahim, Muhammad Faheem, Yasar Shah

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Pharmacokinetics and Pharmacodynamics of Cenerimod, A Selective S1P1R Modulator, Are Not Affected by Ethnicity in Healthy Asian and White Subjects by Pierre‐Eric Juif, Jasper Dingemanse, Peter Winkle, Mike Ufer

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Physiologically‐based pharmacokinetic pharmacodynamic parent‐metabolite model of edoxaban to predict drug-drug‐disease interactions: M4 contribution by Ruijuan Xu, Wenyuan Liu, Weihong Ge, Hua He, Qing Jiang

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Precision Dosing of Meropenem in Adults with Normal Renal Function: Insights from a Population Pharmacokinetic and Monte Carlo Simulation Study by Yong Kyun Kim, Gaeun Kang, Dae Young Zang, Dong Hwan Lee

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Pharmacokinetics of Vancomycin in Healthy Korean Volunteers and Monte Carlo Simulations to Explore Optimal Dosage Regimens in Patients with Normal Renal Function by Yong Kyun Kim, Doee Kim, Gaeun Kang, Dae Young Zang, Dong-Hwan Lee

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