Search Results - "pharmacokinetics"

A phase 1 randomized study of hemodynamic effects and pharmacokinetic interactions during concomitant use of rimegepant and sumatriptan in healthy adults by Robert Croop, Andrea Ivans, Matt S Anderson, Joseph Stringfellow, Richard Bertz, Michael Hanna, Francine Healy, David A Stock, Vladimir Coric, Richard B Lipton

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Corrigendum: Population Pharmacokinetic/Pharmacodynamic Model-Guided Dosing Optimization of a Novel Sedative HR7056 in Chinese Healthy Subjects by Ying Zhou, Ying Zhou, Pei Hu, Yuguang Huang, Nuoer Sang, Kaicheng Song, Hongyun Wang, Jinhua Wen, Ji Jiang, Xia Chen, Xia Chen

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Transferability of Published Population Pharmacokinetic Models for Apixaban and Rivaroxaban to Subjects with Obesity Treated for Venous Thromboembolism: A Systematic Review and External Evaluations by Cyril Leven, Pauline Ménard, Isabelle Gouin-Thibault, Alice Ballerie, Karine Lacut, Edouard Ollier, Jérémie Théreaux

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Pharmacokinetics of a Fixed-Dose Combination of Teneligliptin Hydrochloride Hydrate and Modified-Release Metformin Under Fasting and Fed Conditions in Healthy Subjects by Goak IS, Lee JA, Jeong MH, Moon SJ, Kim MG

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Pharmacokinetic/LDL‐C and exposure-response analysis of tafolecimab in Chinese hypercholesterolemia patients: Results from phase I, II, and III studies by Shuling Yan, Xia Zhao, Qiushi Xie, Weijuan Du, Qingyang Ma, Tongkang Zhu, Huan Deng, Lei Qian, Shirui Zheng, Yimin Cui

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Effect of food on the pharmacokinetics of zoliflodacin granules for oral suspension: Phase I open‐label randomized cross‐over study in healthy subjects by Alison Luckey, Emilie Alirol, Sophie Delhomme, John O'Donnell, Esther Bettiol, John Mueller, Seamus O'Brien, Jean‐Yves Gillon

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Analysis of NSAIDs in Rat Plasma Using 3D-Printed Sorbents by LC-MS/MS: An Approach to Pre-Clinical Pharmacokinetic Studies by Daya Raju Adye, Sachin B. Jorvekar, Upadhyayula Suryanarayana Murty, Subham Banerjee, Roshan M. Borkar

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Pharmacokinetics, pharmacodynamics and safety of 15 mg-tolvaptan administered orally for 7 consecutive days to Chinese patients with child-Pugh B cirrhosis by Hongzhong Liu, Yongfeng Wang, Tao Liu, Yingxuan Chen, Xin Zheng, Ming Liu, Qian Zhao, Minde Zeng, Ji Jiang, Yimin Mao, Pei Hu

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Pharmacokinetic comparison of sitagliptin and metformin HCl extended-release tablets versus JANUMET® XR in healthy volunteers under fasting and fed conditions by Linling Que, Wei Qin, Yunfei Shi, Ying Ding, Kai Huang, Zhenzhong Qian, Bingjie Huang, Peipei Zhou, Qing He

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Pharmacokinetics and Drug-Drug Interactions of Abacavir and Lamuvudine Co-administered With Antituberculosis Drugs in HIV-Positive Children Treated for Multidrug-Resistant Tuberculosis by Louvina E. van der Laan, Louvina E. van der Laan, Anthony J. Garcia-Prats, Anthony J. Garcia-Prats, H. Simon Schaaf, Jana L. Winckler, Heather Draper, Jennifer Norman, Lubbe Wiesner, Helen McIlleron, Paolo Denti, Anneke C. Hesseling

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Repaglinide-loaded nanostructured lipid carriers with different particle sizes for improving oral absorption: preparation, characterization, pharmacokinetics, and in situ intestinal perfusion by Lei Wu, Lin Zhao, Xitong Su, Peng Zhang, Guixia Ling

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Coicis Semen for the treatment of malignant tumors of the female reproductive system: A review of traditional Chinese medicinal uses, phytochemistry, pharmacokinetics, and pharmacodynamics by Xue Pan, Qian Shen, Chuanlong Zhang, Xiyuan Zhang, Yi Li, Zhuo Chang, Bo Pang

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Oral Delivery of Liraglutide-Loaded Zein/Eudragit-Chitosan Nanoparticles Provides Pharmacokinetic and Glycemic Outcomes Comparable to Its Subcutaneous Injection in Rats by Jeferson Ziebarth, Letícia Marina da Silva, Ariane Krause Padilha Lorenzett, Ingrid Delbone Figueiredo, Paulo Fernando Carlstrom, Felipe Nunes Cardoso, André Luiz Ferreira de Freitas, Amanda Martins Baviera, Rubiana Mara Mainardes

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A Phase I Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Novel Intravenous Formulation of Meloxicam (QP001) in Healthy Chinese Subjects by Ma J, Huang J, Zou C, Wu Q, Xie J, Zhang X, Yang X, Yang S, Wu Z, Jiang Y, Yu S, Zhang X, Yang G, Li M

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Evaluation of Placental Transfer and Tissue Distribution of cis- and Trans-Permethrin in Pregnant Rats and Fetuses Using a Physiological-Based Pharmacokinetic Model by Stéphane Personne, Stéphane Personne, Céline Brochot, Paulo Marcelo, Aurélie Corona, Sophie Desmots, Franck Robidel, Anthony Lecomte, Véronique Bach, Florence Zeman

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<i>β</i>-Lactam Pharmacokinetic/Pharmacodynamic Target Attainment in Intensive Care Unit Patients: A Prospective, Observational, Cohort Study by Romain Guilhaumou, Constance Chevrier, Jean Loup Setti, Elisabeth Jouve, Amélie Marsot, Nathan Julian, Olivier Blin, Pierre Simeone, David Lagier, Djamel Mokart, Nicolas Bruder, Marc Garnier, Lionel Velly

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Comprehensive Assessment of Pharmacokinetics, Pharmacodynamics, and Tolerability of Ligelizumab in Healthy Volunteers and Patients with Chronic Spontaneous Urticaria to Optimize Its Subcutaneous Delivery System by Yan Ji, Claudio Calonder, Tiina Kirsilä, Alis Burciu, Matjaz Tisu, Yolandi Joubert, Nathalie Laurent, Eva Hua, Manmath Patekar, Anton Drollmann, Ralph Woessner

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Two-way pharmacokinetic interaction studies between saxagliptin and cytochrome P450 substrates or inhibitors: simvastatin, diltiazem extended-release, and ketoconazole by Patel C, Li L, Girgis S, Kornhauser D, Frevert E, Boulton D

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Pharmacokinetics and bioequivalence study of esomeprazole magnesium enteric-coated tablets 20 mg in healthy Chinese subjects under fasting and fed conditions by Ying Ding, Nannan Chu, Linling Que, Kai Huang, Yuanxing Chen, Wei Qin, Zhenzhong Qian, Yunfei Shi, Zhen Xu, Qing He

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New bioanalytical microemulsion Electrokinetic chromatography method for the simultaneous determination of Trifluridine with its metabolites and Tipiracil in rat plasma: Application to pharmacokinetic studies by Mohamed Hefnawy, Adeeba Alzamil, Hatem Abuelizz, Mona AlShehri

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