Search Results - "pharmacokinetics"

Pharmacokinetic Properties of Three Forms of Vaginal Progesterone Administered in Either Single Or Multiple Dose Regimen in Healthy Post-menopausal Chinese Women by Jianzhong Shentu, Guolan Wu, Junchun Chen, Xingjiang Hu, Huili Zhou, Jian Liu, Duo Lv, Lihua Wu

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Pharmacokinetic Imaging Using ^99mTc-Mebrofenin to Untangle the Pattern of Hepatocyte Transporter Disruptions Induced by Endotoxemia in Rats by Solène Marie, Irene Hernández-Lozano, Marc Le Vée, Louise Breuil, Wadad Saba, Maud Goislard, Sébastien Goutal, Charles Truillet, Oliver Langer, Olivier Fardel, Nicolas Tournier

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Pharmacokinetic and bioequivalence study of a telmisartan/S-amlodipine fixed-dose combination (CKD-828) formulation and coadministered telmisartan and S-amlodipine in healthy subjects by Kang WY, Seong SJ, Ohk B, Gwon M, Kim BK, La S, Kim HJ, Cho S, Yoon Y, Yang DH, Lee HW

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A first‐in‐human oral dose study of mesdopetam (IRL790) to assess its safety, tolerability, and pharmacokinetics in healthy male volunteers by Folke Sjöberg, Susanna Waters, Boel Löfberg, Clas Sonesson, Nicholas Waters, Joakim Tedroff

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In Vitro Evaluation of Poly(lactide-co-glycolide) In Situ Forming Gels for Bedaquiline Fumarate Salt and Pharmacokinetics Following Subcutaneous Injection in Rats by Sandy Van Hemelryck, Rani Wens, Hannelore van Poppel, Milou Luijks, Koosha Shahidi, Marcin Marczak, Ariane Kahnt, René Holm, Erik Mannaert, Peter Langguth

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A review of the botany, ethnopharmacology, phytochemistry, analysis method and quality control, processing methods, pharmacological effects, pharmacokinetics and toxicity of codonopsis radix by Jiaojiao Dong, Yexin Na, Ajiao Hou, Shihao Zhang, Huan Yu, Senwang Zheng, Wei Lan, Liu Yang

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Rituximab pediatric drug development: Pharmacokinetic and pharmacodynamic modeling to inform regulatory approval for rituximab treatment in patients with granulomatosis with polyangiitis or microscopic polyangiitis by Candice Jamois, Leonid Gibiansky, Clarisse Chavanne, Melissa Cheu, Patricia B. Lehane, Pooneh Pordeli, Simone Melega, Jacques Gaudreault

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A Sensitive Liquid Chromatography-Tandem Mass Spectrometry Method for the Determination of Nimbolide in Mouse Serum: Application to a Preclinical Pharmacokinetics Study by Lingzhi Wang, Do-Dang Khoa Phan, Nicholas Syn, Xiaoqiang Xiang, Hongyan Song, Win Lwin Thuya, Shili Yang, Andrea Li-Ann Wong, Alan Prem Kumar, Wei Peng Yong, Gautam Sethi, Paul Chi-Lui Ho, Boon Cher Goh

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The importance of pharmacokinetics and pharmacodynamics in antimicrobial drug development and their influence on the success of agents developed to combat resistant gram negative pathogens: A review by Mary E. Palmer, Lauren J. Andrews, Taylor C. Abbey, Ashley E. Dahlquist, Eric Wenzler

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Study on the Effect of Pharmaceutical Excipient PEG400 on the Pharmacokinetics of Baicalin in Cells Based on MRP2, MRP3, and BCRP Efflux Transporters by Dan Yang, Min Zhang, Mei Zhao, Chaoji Li, Leyuan Shang, Shuo Zhang, Pengjiao Wang, Xiuli Gao

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Matrix Effects of the Hydroethanolic Extract of Calyces of <i>Physalis peruviana</i> L. on Rutin Pharmacokinetics in Wistar Rats Using Population Modeling by Gina Paola Domínguez Moré, María Isabel Cardona, Paula Michelle Sepúlveda, Sandra Milena Echeverry, Cláudia Maria Oliveira Simões, Diana Marcela Aragón

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Comparison of pharmacokinetics and safety between CE-fosphenytoin sodium, fosphenytoin sodium, and phenytoin sodium after intravenous and intramuscular administration in healthy volunteers by Xiaojiao Li, Min Wu, Jixuan Sun, Weili Jin, Lei Han, Jia Xu, Jingrui Liu, Hong Zhang, Jing Wang, Daidi Wang, Hanyi Zhang, Qing Zhang, Nini Liu, Yanhua Ding

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Comparisons of Four Protein-Binding Models Characterizing the Pharmacokinetics of Unbound Phenytoin in Adult Patients Using Non-Linear Mixed-Effects Modeling by Heajin Jun, Yan Rong, Catharina Yih, Jordan Ho, Wendy Cheng, Tony K. L. Kiang

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A New Validated HPLC-MS/MS Method for Quantification and Pharmacokinetic Evaluation of Dovitinib, a Multi-Kinase Inhibitor, in Mouse Plasma by AlRabiah H, Kadi AA, Aljohar HI, Attwa MW, Al-Shakliah NS, Attia SM, Mostafa GAE

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High-altitude Hypoxia Influences the Activities of the Drug-Metabolizing Enzyme CYP3A1 and the Pharmacokinetics of Four Cardiovascular System Drugs by Junbo Zhu, Yabin Duan, Delong Duo, Jianxin Yang, Xue Bai, Guiqin Liu, Qian Wang, Xuejun Wang, Ning Qu, Yang Zhou, Xiangyang Li

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Pharmacokinetic improvement provided by microneedle patch in delivering bee venom, a case study in combating scopolamine-induced neurodegeneration in mouse model by Cong Duc Nguyen, Jaehee Yoo, Eun Jin An, Chang Yub Sung, Do Hyeon Jeong, Soo-Yeon Park, Jae-Hong Kim, Gihyun Lee

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Population pharmacokinetic study in children with vascular anomalies: body weight as a key variable in predicting the initial dose and dosing frequency of sirolimus by Lin Fan, Hong-Li Guo, Yue-Tao Zhao, Yue-Tao Zhao, Yue Li, Wei-Jun Wang, Wei-Jun Wang, Jian Huang, Ya-Hui Hu, Ji-Jun Zou, Feng Chen

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The first selective VAP-1 inhibitor in China, TT-01025-CL: safety, tolerability, pharmacokinetics, and pharmacodynamics of single- and multiple-ascending doses by Yuanxun Yang, Lei Yu, Zejuan Sheng, Hui Lin, Zuyi Weng, Wei Song, Bei Cao, Yu Zhao, Yingsheng Gao, Shumao Ni, Huimin Wang, Tingting Ma, Lei Huang, Caixia Sun, Juan Li

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Physiologically Based Pharmacokinetic (PBPK) Modeling to Predict PET Image Quality of Three Generations EGFR TKI in Advanced-Stage NSCLC Patients by I. H. Bartelink, E. A. van de Stadt, A. F. Leeuwerik, V. L. J. L. Thijssen, J. R. I. Hupsel, J. F. van den Nieuwendijk, I. Bahce, M. Yaqub, N. H. Hendrikse

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Rapid oral transmucosal delivery of zaleplon-lavender oil utilizing self-nanoemulsifying lyophilized tablets technology: development, optimization and pharmacokinetic evaluation by Sarah A. Ali, Nabil A. Alhakamy, Khaled M. Hosny, Eman Alfayez, Deena M. Bukhary, Awaji Y. Safhi, Moutaz Y. Badr, Rayan Y. Mushtaq, Majed Alharbi, Bader Huwaimel, Mohammed Alissa, Sameer Alshehri, Ali H. Alamri, Taha Alqahtani

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