Search Results - "pharmacokinetics"

Preclinical investigation of the pharmacokinetics, metabolism, and protein and red blood cell binding of DRDE-07: a prophylactic agent against sulphur mustard by Pankaj Verma, Rajagopalan Vijayaraghavan

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Pharmacokinetics and safety of deltoid or gluteal injection of aripiprazole lauroxil NanoCrystal Dispersion used for initiation of the long-acting antipsychotic aripiprazole lauroxil by Marjie L. Hard, Angela Wehr, Lisa von Moltke, Yangchun Du, Sarah Farwick, David P. Walling, John Sonnenberg

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Development of Photoremovable Linkers as a Novel Strategy to Improve the Pharmacokinetics of Drug Conjugates and Their Potential Application in Antibody-Drug Conjugates for Cancer Therapy by Audrey Nathania Johan, Yi Li

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Impact of Insulin Tregopil and Its Permeation Enhancer on Pharmacokinetics of Metformin in Healthy Volunteers: Randomized, Open‐Label, Placebo‐Controlled, Crossover Study by Anand Khedkar, Harold Lebovitz, Alexander Fleming, Alan Cherrington, Vinu Jose, Sandeep N. Athalye, Ashwini Vishweswaramurthy

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The Antimicrobial Effects of Colistin Encapsulated in Chelating Complex Micelles for the Treatment of Multi-Drug-Resistant Gram-Negative Bacteria: A Pharmacokinetic Study by Wei-Chuan Liao, Chau-Hui Wang, Tzu-Hui Sun, Yu-Cheng Su, Chia-Hung Chen, Wen-Teng Chang, Po-Lin Chen, Yow-Ling Shiue

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Application of Physiologically Based Pharmacokinetic Modeling to Predict Drug-Drug Interactions between Elexacaftor/Tezacaftor/Ivacaftor and Tacrolimus in Lung Transplant Recipients by Eunjin Hong, Eugeniu Carmanov, Alan Shi, Peter S. Chung, Adupa P. Rao, Kevin Forrester, Paul M. Beringer

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A Novel Berberine-Glycyrrhizic Acid Complex Formulation Enhanced the Prevention Effect to Doxorubicin-Induced Cardiotoxicity by Pharmacokinetic Modulation of Berberine in Rats by Shichang Zhang, Shichang Zhang, Yiwei Zhao, Yiwei Zhao, Liangjun Tan, Liangjun Tan, Sheng Wu, Sheng Wu, Qing Zhang, Qing Zhang, Boxin Zhao, Boxin Zhao, Guofeng Li, Guofeng Li, Guofeng Li

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Stepwise Structural Simplification of the Dihydroxyanthraquinone Moiety of a Multitarget Rhein-Based Anti-Alzheimer Lead to Improve Drug Metabolism and Pharmacokinetic Properties by Caterina Pont, Anna Sampietro, F. Javier Pérez-Areales, Nunzia Cristiano, Agustí Albalat, Belén Pérez, Manuela Bartolini, Angela De Simone, Vincenza Andrisano, Marta Barenys, Elisabet Teixidó, Raimon Sabaté, M. Isabel Loza, José Brea, Diego Muñoz-Torrero

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Population-pharmacokinetic/pharmacodynamic model of atractylodes lancea (Thunb.)... by Teerachat Saeheng, Juntra Karbwang, Kesara Na-Bangchang

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Study of influence of Catha edulis (Khat) chewing on oral pharmacokinetics of irbesartan in rats using a newly developed HPLC-UV method by Hassan A. Alhazmi, Mustafa A. Bakri, Yahya A. Mohzari, Yousef G. Alshigaify, Mohammed Al Bratty, Sadique A. Javed, Asim Najmi, Ziaur Rehman, Waquar Ahsan, Manal Mohamed Elhassan Taha

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Co-Encapsulation of Chlorin e6 and Chemotherapeutic Drugs in a PEGylated Liposome Enhance the Efficacy of Tumor Treatment: Pharmacokinetics and Therapeutic Efficacy by Po-Chun Peng, Ruey-Long Hong, Tsuimin Tsai, Chin-Tin Chen

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Vinblastine pharmacokinetics in mouse, dog, and human in the context of a physiologically based model incorporating tissue‐specific drug binding, transport, and metabolism by Sandra Witta, Keagan P. Collins, Dominique A. Ramirez, Joshua D. Mannheimer, Luke A. Wittenburg, Daniel L. Gustafson

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Novel Solid Self-Nanoemulsifying Drug Delivery System (S-SNEDDS) for Oral Delivery of Olmesartan Medoxomil: Design, Formulation, Pharmacokinetic and Bioavailability Evaluation by Ali Nasr, Ahmed Gardouh, Mamdouh Ghorab

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Physiologically based pharmacokinetic modelling and simulation to predict the plasma concentration profile of schaftoside after oral administration of total flavonoids of Desmodium styracifolium by Xue Li, Chao Chen, Nan Ding, Tianjiao Zhang, Peiyong Zheng, Ming Yang, Ming Yang

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Simultaneous quantitation of folic acid and 5-methyltetrahydrofolic acid in human plasma by HPLCâMS/MS and its application to a pharmacokinetic study by Xiao-Hong Zheng, Li-Yuan Jiang, Lan-Ting Zhao, Quan-Ying Zhang, Li Ding

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A Phase 1 first‐in‐human study of the safety, tolerability, and pharmacokinetics of the ROBO2 fusion protein PF‐06730512 in healthy participants by Chay Ngee Lim, Constantino Kantaridis, Isabelle Huyghe, Donal Gorman, Stephen Berasi, Gabriele E. Sonnenberg

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Population Pharmacokinetic Estimates Suggest Elevated Clearance and Distribution Volume of Desethylamodiaquine in Pediatric Patients with Sickle Cell Disease Treated with Artesunate-Amodiaquine by George O. Adjei, MD, PhD, Seth K. Amponsah, PhD, Bamenla Q. Goka, MB. ChB, MRCP, FWACP, Christabel Enweronu-Laryea, MBBS, MSc, FRCPCH, Lorna Renner, MB. ChB, MPH, FRCPCH, FGCPS, Abdul Malik Sulley, MSc, Michael Alifrangis, MSc, PhD, Jorgen A.L. Kurtzhals, MD, PhD

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Population pharmacokinetics of valproic acid in children with epilepsy: Implications for dose tailoring when switching from oral syrup to sustained‐release tablets by Wei‐Jun Wang, Yue Li, Ya‐Hui Hu, Jie Wang, Yuan‐Yuan Zhang, Lin Fan, Hao‐Ran Dai, Hong‐Li Guo, Xuan‐Sheng Ding, Feng Chen

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Clinical Pharmacokinetic Assessment of Kratom (<i>Mitragyna speciosa</i>), a Botanical Product with Opioid-like Effects, in Healthy Adult Participants by Rakshit S. Tanna, James T. Nguyen, Deena L. Hadi, Preston K. Manwill, Laura Flores-Bocanegra, Matthew E. Layton, John R. White, Nadja B. Cech, Nicholas H. Oberlies, Allan E. Rettie, Kenneth E. Thummel, Mary F. Paine

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Association between Augmented Renal Clearance and Inadequate Vancomycin Pharmacokinetic/Pharmacodynamic Targets in Chinese Adult Patients: A Prospective Observational Study by Jinjin Zhao, Yaxin Fan, Minjie Yang, Xiaoyu Liang, Jufang Wu, Yuancheng Chen, Beining Guo, Huifang Zhang, Ruilan Wang, Fengying Zhang, Jingqing Hang, Huayin Li, Jing Zhang

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