Search Results - "pharmacokinetics"

Simultaneous determination of fourteen components of Gumiganghwal-tang tablet in human plasma by UPLC-ESI-MS/MS and its application to pharmacokinetic study by Seung-Hyun Jeong, Ji-Hun Jang, Guk-Yeo Lee, Seung-Jung Yang, Hea-Young Cho, Yong-Bok Lee

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Enantioselective Box Behenken Optimized HPLC-DAD Method for the Simultaneous Estimation of Alogliptin Enantiomorphs in Pharmaceutical For mulations and their Pharmacokinetic Study in Rat Plasma by Ravi Kant, Ramesh Babu Bodla, Rubina Bhutani, Garima Kapoor

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Effects of a reactive oxygen species generator, napabucasin (BBI608), on tolerability, safety, pharmacokinetics, and QT/QTc interval in healthy volunteers by Naoto Noda, Takeshi Takagaki, Yasuhide Yodo, Yuzo Horibuchi, Shuichi Iino, Shunji Matsuki, Yoichiro Ogama, Hiroyoshi Kakuyama

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Pharmacokinetic comparison of sustained- and immediate-release formulations of cilostazol after multiple oral doses in fed healthy male Korean volunteers by Kim YH, Ghim JL, Jung JA, Cho SH, Choe S, Choi HY, Bae KS, Lim HS

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Population Pharmacokinetic and Pharmacodynamic Analysis of Dalbavancin for Long-Term Treatment of Subacute and/or Chronic Infectious Diseases: The Major Role of Therapeutic Drug Monitoring by Pier Giorgio Cojutti, Sara Tedeschi, Milo Gatti, Eleonora Zamparini, Marianna Meschiari, Paola Della Siega, Maria Mazzitelli, Laura Soavi, Raffaella Binazzi, Elke Maria Erne, Marco Rizzi, Anna Maria Cattelan, Carlo Tascini, Cristina Mussini, Pierluigi Viale, Federico Pea

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Safety, pharmacokinetics, and target engagement of a brain penetrant RIPK1 inhibitor, SAR443820 (DNL788), in healthy adult participants by Agnes Hincelin‐Mery, Xavier Nicolas, Cathy Cantalloube, Robert Pomponio, Pascale Lewanczyk, Myriam Benamor, Dimitry Ofengeim, Emmanuel Krupka, Jennifer Hsiao‐Nakamoto, Amy Eastenson, Nazem Atassi

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Pharmacokinetic Characteristics of Nebulized Colistimethate Sodium Using Two Different Types of Nebulizers in Critically Ill Patients with Ventilator-Associated Respiratory Infections by Anna Kyriakoudi, Konstantinos Pontikis, Georgia Valsami, Stavrina Avgeropoulou, Efthymios Neroutsos, Eirini Christodoulou, Eleni Moraitou, Sophia L. Markantonis, Aristides Dokoumetzidis, Jordi Rello, Antonia Koutsoukou

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Pharmacokinetics and Pharmacodynamics of Esomezol DR, a New Dual Delayed-Release Formulation of Esomeprazole 20 Mg or 40 Mg, in Healthy Subjects by Kim HC, Yang E, Ban MS, Kim YK, Hong SH, Jung J, Jang IJ, Lee S

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Simple and Accurate HPTLC-Densitometric Method for Quantification of Delafloxacin (A Novel Fluoroquinolone Antibiotic) in Plasma Samples: Application to Pharmacokinetic Study in Rats by Prawez Alam, Muzaffar Iqbal, Essam Ezzeldin, Nasr Y. Khalil, Ahmed I. Foudah, Mohammed H. Alqarni, Faiyaz Shakeel

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Bioanalytical method development and validation for the simultaneous estimation of Olanzapine and Samidorphan in rabbit plasma by using HPLC-MS/MS and application to pharmacokinetic study by Rambabu Kantipudi, Sugandha Kumar Pavuluri

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A population pharmacokinetic model is beneficial in quantifying hair concentrations of ritonavir-boosted atazanavir: a study of HIV-infected Zimbabwean adolescents by Bernard Ngara, Simbarashe Zvada, Tariro Dianah Chawana, Babill Stray-Pedersen, Charles Fungai Brian Nhachi, Simbarashe Rusakaniko

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Validated LCâMS/MS method for simultaneous determination of SIM and its acid form in human plasma and cell lysate: Pharmacokinetic application by Tamer A. Ahmed, Jamie Horn, John Hayslip, Markos Leggas

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Ulcerative Colitis and Acute Severe Ulcerative Colitis Patients Are Overlooked in Infliximab Population Pharmacokinetic Models: Results from a Comprehensive Review by Alix Démaris, Ella S. K. Widigson, Johan F. K. F. Ilvemark, Casper Steenholdt, Jakob B. Seidelin, Wilhelm Huisinga, Robin Michelet, Linda B. S. Aulin, Charlotte Kloft

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The Influence of Pharmacogenetics on the Clinical Relevance of Pharmacokinetic Drug-Drug Interactions: Drug-Gene, Drug-Gene-Gene and Drug-Drug-Gene Interactions by Martina Hahn, Sibylle C. Roll

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HPLC-MS/MS method for determination of betamethasone in human plasma with application to a dichorionic twin pregnancy pharmacokinetic and placental transfers studies by Grazielle de Fátima Pinto Rodrigues, Jhohann Richard de Lima Benzi, Maria Paula Marques, Elaine Christine Dantas Moisés, Vera Lucia Lanchote, Alessandra Cristina Marcolin

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Pharmacokinetics of olverembatinib (HQP1351) in the presence of a strong CYP3A4 inhibitor (itraconazole) or inducer (rifampin) in healthy volunteers by Hengbang Wang, Yun Yang, Zi Chen, Lei Fu, Min Yu, Lixin Jiang, Cunlin Wang, Lichuang Men, Ilisse Minto, Dajun Yang, Yifan Zhai

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Pharmacokinetic Study of Four Major Bioactive Components of Liandan Xiaoyan Formula in Ulcerative Colitis and Control Rats Using UPLC-MS/MS by Kaihui Zhang, Zenghui Lu, Qian Wang, Fangle Liu, Meiqi Wang, Chaozhan Lin, Chenchen Zhu

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Effect of MMX® mesalamine coadministration on the pharmacokinetics of amoxicillin, ciprofloxacin XR, metronidazole, and sulfamethoxazole: results from four randomized clinical trials by Pierce D, Corcoran M, Martin P, Barrett K, Inglis S, Preston P, Thompson TN, Willsie SK

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Safety, pharmacokinetics, and pharmacodynamics of sofnobrutinib, a novel non‐covalent BTK inhibitor, in healthy subjects: First‐in‐human phase I study by Kyoko Miyamoto, Robert M. Miller, Christine Voors‐Pette, Jart A. F. Oosterhaven, Marieke van denDobbelsteen, Katsuhiro Mihara, Marian Geldof, Yuji Sato, Naomi Matsuda, Shirou Kirita, Masaaki Sawa, Akinori Arimura

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A Randomized Phase I Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Recombinant Erwinia Asparaginase (JZP‐458) in Healthy Adult Volunteers by Tong Lin, Martha Hernandez‐Illas, Andres Rey, Jack Jenkins, Reddy Chandula, Jeffrey A. Silverman, Mi Rim Choi

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