Search Results - "pharmacokinetics"

Single- and Multiple-Dose Trials to Determine the Pharmacokinetics, Safety, Tolerability, and Sex Effect of Oral Ginsenoside Compound K in Healthy Chinese Volunteers by Lulu Chen, Lulu Chen, Luping Zhou, Luping Zhou, Jie Huang, Yaqin Wang, Yaqin Wang, Guoping Yang, Zhirong Tan, Zhirong Tan, Yicheng Wang, Yicheng Wang, Gan Zhou, Gan Zhou, Jianwei Liao, Jianwei Liao, Dongsheng Ouyang, Dongsheng Ouyang, Dongsheng Ouyang

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Comparative pharmacokinetic study of the five anti-inflammatory active ingredients of Inula cappa in a normal and an LPS-induced inflammatory cell model by Jing Huang, Ruixing Chen, Jie Zhou, Qing Zhang, Cun Xue, Yueting Li, Lin Zheng, Yong Huang, Qun Wang, Yi Chen, Zipeng Gong, Zipeng Gong

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Population Pharmacokinetics and Initial Dose Optimization of Sirolimus Improving Drug Blood Level for Seizure Control in Pediatric Patients With Tuberous Sclerosis Complex by Xiao Chen, Dongdong Wang, Lin Zhu, Jinmiao Lu, Yidie Huang, Guangfei Wang, Yiqing Zhu, Qiaofeng Ye, Yi Wang, Hong Xu, Zhiping Li

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Molecular Docking Investigation, Pharmacokinetic Analysis, and Molecular Dynamic Simulation of Some Benzoxaborole-Benzimidazole Hybrids: An Approach to Identifying Superior Onchocerca Inhibitors by Fabian Audu Ugbe, Gideon Adamu Shallangwa, Adamu Uzairu, Ibrahim Abdulkadir

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Assessment of ibrutinib scheduling on leukocyte, lymph node size and blood pressure dynamics in chronic lymphocytic leukemia through pharmacokinetic‐pharmacodynamic models by Eman I. K. Ibrahim, Mats O. Karlsson, Lena E. Friberg

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Simultaneous determination of multiple components in rat plasma by UPLC-MS/MS for pharmacokinetic studies after oral administration of Pogostemon cablin extract by Yameng Zhu, Yameng Zhu, Huizi Ouyang, Huizi Ouyang, Zhenguo Lv, Guangzhe Yao, Minglei Ge, Xiunan Cao, Yanxu Chang, Jun He

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Optimizing Vancomycin Dosing in Chronic Kidney Disease by Deriving and Implementing a Web-Based Tool Using a Population Pharmacokinetics Analysis by Sreemanee Raaj Dorajoo, Sreemanee Raaj Dorajoo, Chrystal Leandra Winata, Jessica Hui Fen Goh, Jessica Hui Fen Goh, Say Tat Ooi, Jyoti Somani, Lee Ying Yeoh, Siok Ying Lee, Chun Wei Yap, Alexandre Chan, Jung-woo Chae, Jung-woo Chae

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Enhanced Transdermal Delivery of Bisoprolol Hemifumarate via Combined Effect of Iontophoresis and Chemical Enhancers: Ex Vivo Permeation/In Vivo Pharmacokinetic Studies by Mahmoud H. Teaima, Mohamed Azmi Ahmed Mohamed, Randa Tag Abd El Rehem, Saadia A. Tayel, Mohamed A. El-Nabarawi, Shahinaze A. Fouad

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Enhanced gastric therapeutic effects of Brucea javanica oil and its gastroretentive drug delivery system compared to commercial products in pharmacokinetics study by Zhang Y, Zhang L, Zhang Q, Zhang X, Zhang T, Wang B

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Development and pharmacokinetic assessment of a fully canine anti-PD-1 monoclonal antibody for comparative translational research in dogs with spontaneous tumors by Sho Yoshimoto, Nicholas Chester, Ailian Xiong, Enrico Radaelli, Hong Wang, Marc Brillantes, Gayathri Gulendran, Patrick Glassman, Don L. Siegel, Nicola J. Mason

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Development of a Physiologically Based Pharmacokinetic Model for Tegoprazan: Application for the Prediction of Drug-Drug Interactions with CYP3A4 Perpetrators by Lien Thi Ngo, Jaeyeon Lee, Hwi-yeol Yun, Jung-woo Chae

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Minocycline intra-bacterial pharmacokinetic hysteresis as a basis for pharmacologic memory and a backbone for once-a-week pan-tuberculosis therapy by Devyani Deshpande, Shashikant Srivastava, Jotam Garaimunashe Pasipanodya, Tawanda Gumbo, Tawanda Gumbo

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Development of Dual Drug Loaded Nanosized Liposomal Formulation by A Reengineered Ethanolic Injection Method and Its Pre-Clinical Pharmacokinetic Studies by Muhammad Sarfraz, Attia Afzal, Tan Yang, Yongkang Gai, Shahid Masood Raza, Muhammad Waseem Khan, Yao Cheng, Xiang Ma, Guangya Xiang

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Pharmacokinetic variables of medium molecular weight cross linked chitosan nanoparticles to enhance the bioavailability of 5-fluorouracil and reduce the acute oral toxicity by Aisha Sethi, Mahmood Ahmad, Tayyaba Huma, Waqas Ahmad

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A randomized, double‐blind, comparative study of the pharmacodynamics and pharmacokinetics of GP40141 (romiplostim biosimilar) and reference romiplostim in healthy male volunteers by Igor Makarenko, Artem Dorotenko, Sergey Noskov, Veniamin Banko, Valeria Saparova, Alexandr Khokhlov, Evgeniia Zoreeva, Andrey Nedorubov, Bella Zinnatulina, Maria Gefen, Roman Drai

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Therapeutic Drug Monitoring of Mycophenolic Acid as a Precision Medicine Tool for Heart Transplant Patients: Results of an Observational Pharmacokinetic Pilot Study by Francesco Lo Re, Jacopo Angelini, Sandro Sponga, Chiara Nalli, Antonella Zucchetto, Jessica Biasizzo, Ugolino Livi, Massimo Baraldo

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Antioxidant, Alpha-Glucosidase Inhibition Activities, In Silico Molecular Docking and Pharmacokinetics Study of Phenolic Compounds from Native Australian Fruits and Spices by Akhtar Ali, Jeremy J. Cottrell, Frank R. Dunshea

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A compatibility evaluation between the physiologically based pharmacokinetic (PBPK) model and the compartmental PK model using the lumping method with real cases by Hyo-jeong Ryu, Won-ho Kang, Taeheon Kim, Jae Kyoung Kim, Jae Kyoung Kim, Kwang-Hee Shin, Jung-woo Chae, Hwi-yeol Yun

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Physiologically‐Based Pharmacokinetic Modeling of the Drug-Drug Interaction of the UGT Substrate Ertugliflozin Following Co‐Administration with the UGT Inhibitor Mefenamic Acid by Ernesto Callegari, Jian Lin, Susanna Tse, Theunis C. Goosen, Vaishali Sahasrabudhe

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Safety, tolerability and pharmacokinetics of WXFL10203614 in healthy Chinese subjects: A randomized, double-blind, placebo-controlled phase Ⅰ study by Kai Huang, Ying Ding, Linling Que, Nannan Chu, Yunfei Shi, Zhenzhong Qian, Wei Qin, Yuanxin Chen, Xianghong Gu, Jiakun Wang, Zhiwei Zhang, Jianguo Xu, Qing He

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