Search Results - "pharmacokinetics"

First‐in‐human trial assessing the pharmacokinetic‐pharmacodynamic profile of a novel recombinant human chorionic gonadotropin in healthy women and men of reproductive age by Lars‐Erik Broksø Kyhl, Christiane Hesse, Per Larsson, Katharina Bruzelius, Bernadette Mannaerts

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Comparative pharmacokinetics and safety evaluation of high dosage regimens of Andrographis paniculata aqueous extract after single and multiple oral administration in healthy participants by Phanit Songvut, Nuchanart Rangkadilok, Nuchanart Rangkadilok, Nanthanit Pholphana, Tawit Suriyo, Tawit Suriyo, Duangchit Panomvana, Porranee Puranajoti, Jaratluck Akanimanee, Jutamaad Satayavivad, Jutamaad Satayavivad

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Safety, tolerability, and pharmacokinetics of single‐ and multiple‐ascending doses of olamkicept: Results from randomized, placebo‐controlled, first‐in‐human phase I trials by Frank‐Dietrich Wagner, Stefan Schreiber, Yu Bagger, Katharina Bruzelius, Ali Falahati, Ola Sternebring, Arjun Ravi, Philippe Pinton

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Changing the Drug Delivery System: Does It Add to Non-Compliance Ramifications Control? A Simulation Study on the Pharmacokinetics and Pharmacodynamics of Atypical Antipsychotic Drug by Mohammed H. Elkomy

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GSTZ1 genotypes correlate with dichloroacetate pharmacokinetics and chronic side effects in multiple myeloma patients in a pilot phase 2 clinical trial by Dan Dan Tian, Samuel K. Bennett, Lucy A. Coupland, Kathryn Forwood, Yadanar Lwin, Niloofar Pooryousef, Illa Tea, Thy T. Truong, Teresa Neeman, Philip Crispin, James D'Rozario, Anneke C. Blackburn

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Comparative pharmacokinetic study of dosage forms with morpholinium 2-[5-(pyridin-4-yl)-1,2,4-triazol-3-ylthio] acetate by I. V. Bushueva, V. V. Gladyshev, О. I. Panasenko, E. G. Knish

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Integration of a Physiologically Based Pharmacokinetic and Pharmacodynamic Model for Tegoprazan and Its Metabolite: Application for Predicting Food Effect and Intragastric pH Alterations by Hyeon-Cheol Jeong, Min-Gul Kim, Zhuodu Wei, Kyeong-Ryoon Lee, Jaehyeok Lee, Im-Sook Song, Kwang-Hee Shin

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Prediction of Drug-Drug Interactions with Bupropion and Its Metabolites as CYP2D6 Inhibitors Using a Physiologically-Based Pharmacokinetic Model by Caifu Xue, Xunjie Zhang, Weimin Cai

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Population pharmacokinetic and exposure‐response analyses from ALTA‐1L: Model‐based analyses supporting the brigatinib dose in ALK‐positive NSCLC by Neeraj Gupta, Karen L. Reckamp, David R. Camidge, Huub J. Kleijn, Aziz Ouerdani, Francesco Bellanti, John Maringwa, Michael J. Hanley, Shining Wang, Pingkuan Zhang, Karthik Venkatakrishnan

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Exploring Toxins for Hunting SARS-CoV-2 Main Protease Inhibitors: Molecular Docking, Molecular Dynamics, Pharmacokinetic Properties, and Reactome Study by Mahmoud A. A. Ibrahim, Alaa H. M. Abdelrahman, Laila A. Jaragh-Alhadad, Mohamed A. M. Atia, Othman R. Alzahrani, Muhammad Naeem Ahmed, Moustafa Sherief Moustafa, Mahmoud E. S. Soliman, Ahmed M. Shawky, Paul W. Paré, Mohamed-Elamir F. Hegazy, Peter A. Sidhom

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Pharmacokinetics and bioavailability of single dose ibuprofen and pseudoephedrine alone or in combination: a randomized three-period, cross-over trial in healthy Indian volunteers by Prashant eKale

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Discovery of highly selective and orally available benzimidazole-based phosphodiesterase 10 inhibitors with improved solubility and pharmacokinetic properties for treatment of pulmonary arterial hypertension by Yuncong Yang, Sirui Zhang, Qian Zhou, Chen Zhang, Yuqi Gao, Hao Wang, Zhe Li, Deyan Wu, Yinuo Wu, Yi-You Huang, Lei Guo, Hai-Bin Luo

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Development of quantification methods of a new selective carbonic anhydrase II inhibitor in plasma and blood and study of the pharmacokinetics of its ophthalmic suspension in rats by Alexander L. Khokhlov, Ilya I. Yaichkov, Mikhail K. Korsakov, Anton A. Shetnev, Nikita N. Volkhin, Sergey S. Petukhov

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Population pharmacokinetic‐pharmacodynamic modeling of clopidogrel for dose regimen optimization based on CYP2C19 phenotypes: A proof of concept study by Yun Seob Jung, Byung Hak Jin, Min Soo Park, Choon Ok Kim, Dongwoo Chae

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Use of High-Dose Nebulized Colistimethate in Patients with Colistin-Only Susceptible <i>Acinetobacter baumannii</i> VAP: Clinical, Pharmacokinetic and Microbiome Features by Gennaro De Pascale, Gabriele Pintaudi, Lucia Lisi, Flavio De Maio, Salvatore Lucio Cutuli, Eloisa Sofia Tanzarella, Simone Carelli, Gianmarco Lombardi, Melania Cesarano, Veronica Gennenzi, Gabriella Maria Pia Ciotti, Domenico Luca Grieco, Brunella Posteraro, Maurizio Sanguinetti, Pierluigi Navarra, Massimo Antonelli

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Applications, phytochemistry, pharmacological effects, pharmacokinetics, toxicity of Scutellaria baicalensis Georgi. and its probably potential therapeutic effects on COVID-19: a review by Jia-Wen Song, Jia-Ying Long, Long Xie, Lin-Lin Zhang, Qing-Xuan Xie, Hui-Juan Chen, Mao Deng, Xiao-Fang Li

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Pharmacokinetic and Pharmacodynamic Effects of Oral CXA‐10, a Nitro Fatty Acid, After Single and Multiple Ascending Doses in Healthy and Obese Subjects by Rachel M. Garner, Diane R. Mould, Carla Chieffo, Diane K. Jorkasky

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Pharmacokinetic Differences of Wuji Pill Components in Normal and Chronic Visceral Hypersensitivity Irritable Bowel Syndrome Rats Attributable to Changes in Tight Junction and Transporters by Zipeng Gong, Zipeng Gong, Qing Yang, Yajie Wang, Xiaogang Weng, Yujie Li, Yu Dong, Xiaoxin Zhu, Ying Chen

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A 42-Markers Pharmacokinetic Study Reveals Interactions of Berberine and Glycyrrhizic Acid in the Anti-diabetic Chinese Medicine Formula Gegen-Qinlian Decoction by Xue Qiao, Qi Wang, Shuang Wang, Yi Kuang, Kai Li, Wei Song, Min Ye

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Dipeptidyl Peptidase IV Inhibitory Peptides from Chickpea Proteins (<i>Cicer arietinum</i> L.): Pharmacokinetics, Molecular Interactions, and Multi-Bioactivities by José Antonio Mora-Melgem, Jesús Gilberto Arámburo-Gálvez, Feliznando Isidro Cárdenas-Torres, Jhonatan Gonzalez-Santamaria, Giovanni Isaí Ramírez-Torres, Aldo Alejandro Arvizu-Flores, Oscar Gerardo Figueroa-Salcido, Noé Ontiveros

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