Search Results - "pharmacokinetics"

Development and optimization of multivesicular gefitinib liposomal transdermal system employing lipoid S100 for breast cancer: pharmacokinetics, bioavailability, and skin irritation studies in Wistar rats by Jyoti S. Patel, Nulgumnalli Manjunathaiah Raghavendra, B. Sajeev Kumar

Connect to this object online.

Population pharmacokinetic analysis of TQ-B3203 following intravenous administration of TQ-B3203 liposome injection in Chinese patients with advanced solid tumors by Xiaoqing Li, Yunhai Bo, Han Yin, Xiaohong Liu, Xu Li, Fen Yang

Connect to this object online.

Case Report: Monitoring Vancomycin Concentrations and Pharmacokinetic Parameters in Continuous Veno-Venous Hemofiltration Patients to Guide Individualized Dosage Regimens: A Case Analysis by Jihui Chen, Xiaohui Huang, Zhiyan Lin, Chao Li, Haoshu Ding, Junming Du, Lixia Li

Connect to this object online.

Model-Informed Drug Development of New Cefoperazone Sodium and Sulbactam Sodium Combination (3:1): Pharmacokinetic/Pharmacodynamic Analysis and Antibacterial Efficacy Against Enterobacteriaceae by Xi-Wei Ji, Xiao Zhu, Yun Li, Feng Xue, Isabelle Hui San Kuan, Isabelle Hui San Kuan, Qing-Feng He, Xiang-Rui Meng, Xiao-Qiang Xiang, Yi-Min Cui, Bo Zheng

Connect to this object online.

Pharmacokinetics of a Cytochrome P450 2E1 Probe, Chlorzoxazone, and its 6-Hydroxy Metabolite in Poloxamer 407-Induced Hyperlipidemic Rats by Mi Hye Kwon, Cheol Jung Lee, Yong Yeon Cho, Hee Eun Kang

Connect to this object online.

Comparative Pharmacokinetics of Three Bioactive Diterpenoids of Rabdosia serra Extract in Normal and Con A-Induced Liver Injury Rats Using UPLC-MS/MS by Fangle Liu, Fangle Liu, Yun Zeng, Pengyu Dai, Kaiwen Huang, Kaihui Zhang, Tao Tao, Meiqi Wang, Chenchen Zhu, Chaozhan Lin

Connect to this object online.

Generic Workflow to Predict Medicine Concentrations in Human Milk Using Physiologically-Based Pharmacokinetic (PBPK) Modelling-A Contribution from the ConcePTION Project by Nina Nauwelaerts, Julia Macente, Neel Deferm, Rodolfo Hernandes Bonan, Miao-Chan Huang, Martje Van Neste, David Bibi, Justine Badee, Frederico S. Martins, Anne Smits, Karel Allegaert, Thomas Bouillon, Pieter Annaert

Connect to this object online.

Drug-drug interactions between pemafibrate and statins on pharmacokinetics in healthy male volunteers: Open‐label, randomized, 6‐sequence, 3‐period crossover studies by Tomohiro Kamimura, Neil Hounslow, Hideki Suganami, Ryohei Tanigawa

Connect to this object online.

Randomized single oral dose phase 1 study of safety, tolerability, and pharmacokinetics of Iminosugar UV-4 Hydrochloride (UV-4B) in healthy subjects. by Michael Callahan, Anthony M Treston, Grace Lin, Marla Smith, Brian Kaufman, Mansoora Khaliq, Lisa Evans DeWald, Kevin Spurgers, Kelly L Warfield, Preeya Lowe, Matthew Duchars, Aruna Sampath, Urban Ramstedt

Connect to this object online.

A Promising Single Oral Disintegrating Tablet for Co-Delivery of Pitavastatin Calcium and Lornoxicam Using Co-Processed Excipients: Formulation, Characterization and Pharmacokinetic Study by Teaima MH, Abdel-Haleem KM, Osama R, El-Nabarawi MA, Elnahas OS

Connect to this object online.

Comparative Pharmacokinetics of Hydrophilic Components in Salvia miltiorrhiza Bge. and Carthamus tinctorius L. in Rats That Underwent Cerebral Ischemia Reperfusion Using an HPLC-DAD Method by Xixi Zhao, Li Yu, Yulin Chen, Yu Wang, Haitong Wan, Jiehong Yang

Connect to this object online.

Bioanalytical Assay Development and Validation for the Pharmacokinetic Study of GMC1, a Novel FKBP52 Co-chaperone Inhibitor for Castration Resistant Prostate Cancer by Oscar Ekpenyong, Candace Cooper, Jing Ma, Naihsuan C. Guy, Ashley N. Payan, Fuqiang Ban, Artem Cherkasov, Marc B. Cox, Dong Liang, Huan Xie

Connect to this object online.

Comparable pharmacokinetics and pharmacodynamics of two epoetin alfa formulations Eporon® and Eprex® following a single subcutaneous administration in healthy male volunteers by Yoon S, Rhee SJ, Heo SJ, Oh TY, Yoon SH, Cho JY, Lee S, Yu KS

Connect to this object online.

A phase I randomized, double‐blinded, placebo‐controlled study assessing the safety and pharmacokinetics of RIPK1 inhibitor GFH312 in healthy subjects by Jason Lickliter, Shuang Wang, Wenxin Zhang, Huaqiang Zhu, Jing Wang, Congqiao Zhao, Haige Shen, Yu Wang

Connect to this object online.

Development, validation of liquid chromatography-tandem mass spectrometry method for simultaneous determination of rosuvastatin and metformin in human plasma and its application to a pharmacokinetic study by P Pavan Kumar, T. E. G. K. Murthy, M V Basaveswara Rao

Connect to this object online.

A Phase 1, Randomized, Double-Blind, Single-Dose, Placebo-Controlled Safety, Tolerability, And Pharmacokinetic/Pharmacodynamic Study Of Evolocumab In Healthy Chinese Subjects by Liu C, Lu H, Yuan F, Chen WL, Xu HR, Li H, Hsu CP, Egbuna O, Wu J, Dias C, Abosaleem B, Rana J, Monsalvo ML, Li XN, Yu Z

Connect to this object online.

IVIVC assessment, pharmacokinetic evaluation, and X-ray radiography mapping of Novel Parteck® SRP 80 and hypromellose-loaded LTD4 receptor antagonist chronosystem by Saniya Jawed, C. S. Satish

Connect to this object online.

Phase 1 safety, tolerability, and pharmacokinetic study of single ascending doses of XM17 (recombinant human follicle-stimulating hormone) in downregulated healthy women by Lammerich A, Bias P, Gertz B

Connect to this object online.

Open-Label, Phase I, Pharmacokinetic Studies in Healthy Chinese Subjects to Evaluate the Bioequivalence and Food Effect of a Novel Formulation of Abiraterone Acetate Tablets by Feng Z, Liu Y, Kuang Y, Yang S, Li J, Ye L, Huang J, Pei Q, Huang Y, Yang G

Connect to this object online.

Investigation of CYP3A induction by PF‐05251749 in early clinical development: comparison of linear slope physiologically based pharmacokinetic prediction and biomarker response by Jian Lin, Francois Gaudreault, Nathaniel Johnson, Zhiwu Lin, Parya Nouri, Theunis C. Goosen, Aarti Sawant‐Basak

Connect to this object online.