Search Results - "pharmacokinetics"

Effect of CYP3A5 Genotypes on the Pharmacokinetics of Carbamazepine when used as Monotherapy or Co-Administered with Phenytoin, Phenobarbital or Valproic Acid in Thai Patients by Duangchit Panomvana, Tharathorn Traiyawong, Somchai Towanabut

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Pharmacokinetic comparison of a fixed-dose combination versus concomitant administration of fimasartan, amlodipine, and rosuvastatin using partial replicated design in healthy adult subjects by Oh M, Ghim JL, Park SE, Kim EY, Shin JG

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Pharmacokinetics and Metabolite Profiling of Trepibutone in Rats Using Ultra-High Performance Liquid Chromatography Combined With Hybrid Quadrupole-Orbitrap and Triple Quadrupole Mass Spectrometers by Zhi Sun, Zhi Sun, Jie Yang, Jie Yang, Liwei Liu, Liwei Liu, Yanyan Xu, Yanyan Xu, Lin Zhou, Lin Zhou, Qingquan Jia, Yingying Shi, Yingying Shi, Xiangyu Du, Jian Kang, Jian Kang, Lihua Zuo, Lihua Zuo

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A Semi-Mechanistic Population Pharmacokinetic Model of Noscapine in Healthy Subjects Considering Hepatic First-Pass Extraction and CYP2C9 Genotypes by Zhendong Chen, Max Taubert, Chunli Chen, Jana Boland, Qian Dong, Muhammad Bilal, Charalambos Dokos, Bertil Wachall, Manfred Wargenau, Bernhard Scheidel, Martin H. J. Wiesen, Elke Schaeffeler, Roman Tremmel, Matthias Schwab, Uwe Fuhr

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Pharmacokinetic/pharmacodynamic issues for optimizing treatment with beta-lactams of Gram-negative infections in critically ill orthotopic liver transplant recipients: a comprehensive review by Milo Gatti, Milo Gatti, Federico Pea, Federico Pea

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Pharmacokinetics of single‐dose rivaroxaban under fed state in obese vs. non‐obese subjects: An open‐label controlled clinical trial (RIVOBESE‐PK) by Majdoleen Alalawneh, Ahmed Awaisu, Ibtihal Abdallah, Hazem Elewa, Mohammed Danjuma, Kamal M. Matar, Akram M. ElKashlan, Yasser Elshayep, Fathy Ibrahim, Ousama Rachid

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Novel protocol for multiple-dose oral administration of the L-type Ca2+ channel blocker isradipine in mice: A dose-finding pharmacokinetic study by Tamara Theiner, Nadine J. Ortner, Herbert Oberacher, Gospava Stojanovic, Petronel Tuluc, Jörg Striessnig

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The Development and Validation of a Novel "Dual Cocktail" Probe for Cytochrome P450s and Transporter Functions to Evaluate Pharmacokinetic Drug-Drug and Herb-Drug Interactions by Mihwa Kwon, Ji-Hyeon Jeon, Min-Koo Choi, Im-Sook Song

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Quantitative prediction of pharmacokinetic properties of drugs in humans: Recent advance in in vitro models to predict the impact of efflux transporters in the small intestine and blood-brain barrier by Yoshiki Hashimoto, Kazuyoshi Michiba, Kazuya Maeda, Hiroyuki Kusuhara

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Influence of Hydrophobic Side-Chain Length in Amphiphilic Gradient Copoly(2-oxazoline)s on the Therapeutics Loading, Stability, Cellular Uptake and Pharmacokinetics of Nano-Formulation with Curcumin by Shubhashis Datta, Veronika Huntošová, Annamária Jutková, Róbert Seliga, Juraj Kronek, Adriána Tomkova, Lenka Lenkavská, Mariana Máčajová, Boris Bilčík, Barbora Kundeková, Ivan Čavarga, Ewa Pavlova, Miroslav Šlouf, Pavol Miškovský, Daniel Jancura

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Effect of ABCB1 Gene Carriage and Drug-Drug Interactions on Apixaban and Rivaroxaban Pharmacokinetics and Clinical Outcomes in Patients with Atrial Fibrillation and Deep Vein Thrombosis by L. V. Fedina, I. N. Sychev, T. D. Rastvorova, E. V. Strigunkova, A. A. Kachanova, Z. A. Sozaeva, P. O. Bochkov, A. V. Vardanyan, K. B. Mirzayev, D. A. Sychev

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Pharmacokinetics, Pharmacodynamics and Drug-Drug Interactions of New Anti-Migraine Drugs-Lasmiditan, Gepants, and Calcitonin-Gene-Related Peptide (CGRP) Receptor Monoclonal Antibodies by Danuta Szkutnik-Fiedler

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A Phase 1, Multicenter, Open-Label Study to Evaluate the Pharmacokinetics of Iberdomide in Subjects with Mild, Moderate, or Severe Hepatic Impairment Compared with Healthy Subjects by Cheng Y, Ye Y, Gaudy A, Ghosh A, Xue Y, Wang A, Zhou S, Li Y

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Initial dosage optimisation of cyclosporine in Chinese paediatric patients undergoing allogeneic haematopoietic stem cell transplantation based on population pharmacokinetics: a retrospective study by Yan Li, Sha Liu, Hua Jiang, Wei Zheng, Min Huang, Huanwen Feng, Xianggui Wang, Yuxian Lin, Haojie Qiu, Teng Fong Chan, Xiaolan Mo, Jiali Li

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Absence of a significant pharmacokinetic interaction between atorvastatin and fenofibrate: A randomized, crossover, study of a fixed-dose formulation in healthy Mexican subjects by Omar ePatiño-Rodríguez, Rosa María eMartínez-Medina, Irma eTorres-Roque, Maricela eMartínez-Delgado, America Susana Mares-Garcia, Abraham eEscobedo-Moratilla, Amador eCovarrubias-Pinedo, Angélica eArzola-Paniagua, José Luis eHerrera-Torres, José ePérez-Urizar

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Safety, tolerance, and pharmacokinetics of salvianolic acid B in healthy Chinese volunteers: A randomized, double-blind, placebo-controlled phase 1 clinical trial by Junlin Cheng, Jun Long, Jingjing Zhang, Le Han, Yunfang Hu, Jianghui Liu, Runze Qiu, Zhibin Zhu, Hongwei Fan

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Vancomycin Area under the Concentration-Time Curve Estimation Using Bayesian Modeling versus First-Order Pharmacokinetic Equations: A Quasi-Experimental Study by Yazed Saleh Alsowaida, David W. Kubiak, Brandon Dionne, Mary P. Kovacevic, Jeffrey C. Pearson

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A phase I, single and continuous dose administration study on the safety, tolerability, and pharmacokinetics of neorudin, a novel recombinant anticoagulant protein, in healthy subjects by Yubin Liu, Meixia Wang, Xiaona Dong, Jia He, Lin Zhang, Ying Zhou, Xia Xia, Guifang Dou, Chu‐tse Wu, Jide Jin

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Fluorescence Detection of Zabofloxacin, a Novel Fluoroquinolone Antibiotic, in Plasma, Bile, and Urine by HPLC: The First Oral and Intravenous Applications in a Pharmacokinetic Study in Rats by Hyo Eon Jin, In Hyul Kang, Chang Koo Shim

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Pharmacokinetics of prednisolone in children: an open-label, randomised, two-treatment cross-over trial investigating the bioequivalence of different prednisolone formulations in children with airway disease by Sissel Sundell Haslund-Krog, Helle Holst, Maria Schmidt, Ron Mathot, Andreas Kryger Jensen, Inger Merete Jørgensen

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