Search Results - "pharmacokinetics"

Therapeutic Doses of Eltrombopag do not Inhibit Hepatic BCRP in Healthy Volunteers: Intravenous Ceftriaxone as a Model by Daniel Valente Neves, Carolina Pinto Vieira, Adriana Rocha, Vera Lucia Lanchote

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P-Glycoprotein (ABCB1/MDR1) and BCRP (ABCG2) Limit Brain Accumulation and Cytochrome P450-3A (CYP3A) Restricts Oral Exposure of the RET Inhibitor Selpercatinib (RETEVMO) by Yaogeng Wang, Rolf W. Sparidans, Sander Potters, Rahime Şentürk, Maria C. Lebre, Jos H. Beijnen, Alfred H. Schinkel

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Investigation of the Inhibitory Effect of Simvastatin on the Metabolism of Lidocaine Both in vitro and in vivo by Wang Y, Ou-yang Q, Huang W, Huang H, Zhuang X, Lin Q, Zeng D

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High-fat diets enhance and delay ursodeoxycholic acid absorption but elevate circulating hydrophobic bile salts by Liang Huang, Liang Huang, Wei Wei, Xiaomei Huang, Xuejing Li, Haisha Liu, Lanlan Gui, Lanlan Gui, Jinping Jiang, Linfei Wan, Xiangxiang Zhou, Jingsong Ding, Xuehua Jiang, Bikui Zhang, Ke Lan, Ke Lan

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Radiation Increases Bioavailability of Lisinopril, a Mitigator of Radiation-Induced Toxicities by Meetha Medhora, Meetha Medhora, Meetha Medhora, Meetha Medhora, Meetha Medhora, Preeya Phadnis, Jayashree Narayanan, Tracy Gasperetti, Jacek Zielonka, Jacek Zielonka, John E. Moulder, Brian L. Fish, Aniko Szabo

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Development of Arteannuin B Sustained-Release Microspheres for Anti-Tumor Therapy by Integrated Experimental and Molecular Modeling Approaches by Yanqing Wang, Weijuan Huang, Nannan Wang, Defang Ouyang, Lifeng Xiao, Sirui Zhang, Xiaozheng Ou, Tingsha He, Rongmin Yu, Liyan Song

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A New Framework to Implement Model-Informed Dosing in Clinical Guidelines: Piperacillin and Amikacin as Proof of Concept by Stan J. F. Hartman, Joost G. E. Swaving, Stijn W. van Beek, Bianca D. van Groen, Marika de Hoop, Marika de Hoop, Tjitske M. van der Zanden, Tjitske M. van der Zanden, Rob ter Heine, Saskia N. de Wildt, Saskia N. de Wildt, Saskia N. de Wildt, Saskia N. de Wildt

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Study of the ketohexokinase inhibitor PF‐06835919 as a clinical cytochrome P450 3A inducer: Integrated use of oral midazolam and liquid biopsy by Ruolun Qiu, Kari Fonseca, Arthur Bergman, Jian Lin, David Tess, Lauren Newman, Alia Fahmy, Zivile Useckaite, Andrew Rowland, Manoli Vourvahis, David Rodrigues

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Computational approach towards the design of artemisinin-thymoquinone hybrids against main protease of SARS-COV-2 by Victor Moreira de Oliveira, Matheus Nunes da Rocha, Emanuel Paula Magalhães, Francisco Rogênio da Silva Mendes, Márcia Machado Marinho, Ramon Róseo Paula Pessoa Bezerra de Menezes, Tiago Lima Sampaio, Hélcio Silva dos Santos, Alice Maria Costa Martins, Emmanuel Silva Marinho

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Pharmacometric Analysis of Intranasal and Intravenous Nalbuphine to Optimize Pain Management in Infants by Miriam Pfiffner, Eva Berger-Olah, Priska Vonbach, Priska Vonbach, Marc Pfister, Verena Gotta

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Anti-infective Medicines Use in Children and Neonates With Pre-existing Kidney Dysfunction: A Systematic Review by Chiara Minotti, Elisa Barbieri, Denis Doni, Cristina Impieri, Carlo Giaquinto, Daniele Donà

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Orally Administered Koumine Persists Longer in the Plasma of Aged Rats Than That of Adult Rats as Assessed by Ultra-Performance Liquid Chromatography-Tandem Mass Spectrometry by Li-Xiang Ye, Ying Xu, Shui-Hua Zhang, Da-Xuan Cao, Ling-Fan Chen, Yan-Ping Su, Hui-Hui Huang, Chang-Xi Yu, Chang-Xi Yu, Chang-Xi Yu

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A randomized, double-blind, placebo-controlled phase I trial of inhalation treatment of recombinant TFF2-IFN protein: A multifunctional candidate for the treatment of COVID-19 by Yan Liu, Yan Liu, Guanxing Zhai, Weihui Fu, Xiaoyan Zhang, Xiaoyan Zhang, Jianqing Xu, Jianqing Xu

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Total Coumarins from Hydrangea paniculata Show Renal Protective Effects in Lipopolysaccharide-Induced Acute Kidney Injury via Anti-inflammatory and Antioxidant Activities by Sen Zhang, Jie Ma, Li Sheng, Dongming Zhang, Xiaoguang Chen, Jingzhi Yang, Dongjie Wang

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In vitro, in vivo, and in silico approaches for evaluating the preclinical DMPK profiles of ammoxetine, a novel chiral serotonin and norepinephrine reuptake inhibitor by Xiuqing Zhu, Xiuqing Zhu, Yuexin Li, Huan Luo, Yunxia Zhang, Zhenqing Zhang, Jinglai Li

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Lorazepam-Induced Memory Deficits by J Gordon Millichap

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Neonatal pharmacology and clinical implications by Antonio Ruggiero, Anna Ariano, Silvia Triarico, Michele Antonio Capozza, Pietro Ferrara, Giorgio Attinà

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Drug-Drug Interactions at Organic Cation Transporter 1 by Shiwei Zhou, Shiwei Zhou, Shiwei Zhou, Sujuan Zeng, Yan Shu, Yan Shu

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Factors, effecting on drug bioavailability by P. . Bochkov, R. . Shevchenko, A. . Litvin, G. . Kolyvanov, V. . Zherdev

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Clinical Pharmacology of Hormonal Emergency Contraceptive Pills by Celia M. J. Matyanga, Blessing Dzingirai

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