Search Results - "pharmacokinetics"

Association between Extended Meropenem Regimen and Achievement of Aggressive PK/PD in Patients Receiving Continuous Renal Replacement Therapy for Septic AKI by Shinya Chihara, Tomoyuki Ishigo, Satoshi Kazuma, Kana Matsumoto, Kunihiko Morita, Yoshiki Masuda

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Designing phase I oncology dose escalation using dose-exposure-toxicity models as a complementary approach to model‐based dose-toxicity models by Kristyn Pantoja, Shankar Lanke, Alain Munafo, Anja Victor, Christina Habermehl, Armin Schueler, Karthik Venkatakrishnan, Pascal Girard, Kosalaram Goteti

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Preparation and evaluation of Vinpocetine self-emulsifying pH gradient release pellets by Mengqi Liu, Shiming Zhang, Shuxia Cui, Fen Chen, Lianqun Jia, Shu Wang, Xiumei Gai, Pingfei Li, Feifei Yang, Weisan Pan, Xinggang Yang

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Clinical pharmacology and tolerability of REC‐994, a redox‐cycling nitroxide compound, in randomized phase 1 dose‐finding studies by Ron Alfa, Timothy Considine, Shafique Virani, Matt Pfeiffer, Anthony Donato, Daniel Dickerson, Diana Shuster, Joel Ellis, Kristen Rushton, Helen Wei, Christopher Gibson

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A strategy for the efficient construction of anti-PD1-based bispecific antibodies with desired IgG-like properties by Jie Zhao, Liangfeng Jiang, Haodong Yang, Lan Deng, Xiaoqing Meng, Jian Ding, Sixing Yang, Le Zhao, Wei Xu, Xiaolong Wang, Zhenping Zhu, Haomin Huang

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A System Pharmacology Model for Decoding the Synergistic Mechanisms of Compound Kushen Injection in Treating Breast Cancer by Yi Li, Kexin Wang, Kexin Wang, Yupeng Chen, Yupeng Chen, Jieqi Cai, Jieqi Cai, Xuemei Qin, Aiping Lu, Daogang Guan, Daogang Guan, Genggeng Qin, Weiguo Chen

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A practical strategy to subcutaneous administered in-situ gelling co-delivery system of arsenic and retinoic acid for the treatment of acute promyelocytic leukemia by Xiao Liu, Weiwei Yin, Andy Samuel Widjaya, Yueying Yang, Yunhu Liu, Yanyan Jiang

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A dynamic model of the intestinal epithelium integrates multiple sources of preclinical data and enables clinical translation of drug‐induced toxicity by Louis Gall, Ferran Jardi, Lieve Lammens, Janet Piñero, Terezinha M. Souza, Daniela Rodrigues, Danyel G. J. Jennen, Theo M. deKok, Luke Coyle, Seung‐Wook Chung, Sofia Ferreira, Heeseung Jo, Kylie A. Beattie, Colette Kelly, Carrie A. Duckworth, D. Mark Pritchard, Carmen Pin

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Use of In Vivo Imaging and Physiologically-Based Kinetic Modelling to Predict Hepatic Transporter Mediated Drug-Drug Interactions in Rats by Nicola Melillo, Daniel Scotcher, J. Gerry Kenna, Claudia Green, Catherine D. G. Hines, Iina Laitinen, Paul D. Hockings, Kayode Ogungbenro, Ebony R. Gunwhy, Steven Sourbron, John C. Waterton, Gunnar Schuetz, Aleksandra Galetin

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In silico identification of promiscuous scaffolds as potential inhibitors of 1-deoxy-d-xylulose 5-phosphate reductoisomerase for treatment of Falciparum malaria by Abdul Wadood, Mehreen Ghufran, Syed Fahad Hassan, Huma Khan, Syed Sikandar Azam, Umer Rashid

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Orally Administered Crocin Protects Against Cerebral Ischemia/Reperfusion Injury Through the Metabolic Transformation of Crocetin by Gut Microbiota by Yue Zhang, Jianliang Geng, Yu Hong, Li Jiao, Shuning Li, Runbin Sun, Yuan Xie, Caixia Yan, Jiye Aa, Guangji Wang

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Remogliflozin Etabonate in the Treatment of Type 2 Diabetes: Design, Development, and Place in Therapy by Mohan V, Mithal A, Joshi SR, Aravind SR, Chowdhury S

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Phytochemical Profiling, In Vitro Biological Activities, and In-Silico Studies of <i>Ficus vasta Forssk.</i>: An Unexplored Plant by Hanan Y. Aati, Mariyam Anwar, Jawaher Al-Qahtani, Areej Al-Taweel, Kashif-, Sultan Aati, Faisal Usman, Bilal Ahmad Ghalloo, Hafiz Muhammad Asif, Jafir Hussain Shirazi, Aliza Abbasi

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Wettability and contact angle affect precorneal retention and pharmacodynamic behavior of microspheres by Hanyu Liu, Xinyue Han, Huamei Li, Qi Tao, Jie Hu, Shuo Liu, Huaixin Liu, Jun Zhou, Wei Li, Fan Yang, Qineng Ping, Shijie Wei, Hongmei Liu, Huaqing Lin, Dongzhi Hou

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Evaluation of Real-World Vancomycin Dosing and Attainment of Therapeutic Drug Monitoring Targets by Nicole Bradley, Kimberly Ng

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Kreon^® (Creon^®) vs. Lipancrea^®: <i>In Vitro</i> Comparison of Two Encapsulated Pancreatin Preparations by Sven Hartmann, Grazyna Rydzewska, J. Enrique Domínguez-Muñoz

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Solid lipid nanoparticles loaded with iron to overcome barriers for treatment of iron deficiency anemia by Hosny KM, Banjar ZM, Hariri AH, Hassan AH

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Selective Serotonin Reuptake Inhibitors and Adverse Effects: A Narrative Review by Amber N. Edinoff, Haseeb A. Akuly, Tony A. Hanna, Carolina O. Ochoa, Shelby J. Patti, Yahya A. Ghaffar, Alan D. Kaye, Omar Viswanath, Ivan Urits, Andrea G. Boyer, Elyse M. Cornett, Adam M. Kaye

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Piperacillin Steady State Concentrations in Target Tissues Relevant for PJI Treatment-A Randomized Porcine Microdialysis Study Comparing Continuous Infusion with Intermittent Short... by Hans Christian Rasmussen, Pelle Hanberg, Martin Knudsen, Sara Kousgaard Tøstesen, Andrea René Jørgensen, Elisabeth Krogsgaard Petersen, Kristina Öbrink-Hansen, Kjeld Søballe, Maiken Stilling, Mats Bue

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Model‐informed pediatric dose selection of marzeptacog alfa (activated): An exposure matching strategy by Alan Faraj, Rob C. vanWijk, Linda Neuman, Shraddha Desai, Grant E. Blouse, Tom Knudsen, Ulrika S. H. Simonsson

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