Search Results - "pharmacokinetics"

A Window for Enhanced Oral Delivery of Therapeutics via Lipid Nanoparticles by Amekyeh H, Sabra R, Billa N

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Targeted co-delivery biomimetic nanoparticles reverse macrophage polarization for enhanced rheumatoid arthritis therapy by Xiu Zheng, Xin Yu, Chenglong Wang, Yan Liu, Ming Jia, Fenting Lei, Ji Tian, Chunhong Li

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Clinical trial evaluating apomorphine oromucosal solution in Parkinson's disease patients by Eva Thijssen, Bert Tuk, Michel Cakici, Veerle vanVelze, Erica Klaassen, Frans Merkus, Teus vanLaar, Philip Kremer, Geert Jan Groeneveld

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Impact of CNS Diseases on Drug Delivery to Brain Extracellular and Intracellular Target Sites in Human: A "WHAT-IF" Simulation Study by Mohammed A. A. Saleh, Elizabeth C. M. de Lange

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Establishing a Relationship between In Vitro Potency in Cell-Based Assays and Clinical Efficacious Concentrations for Approved GLP-1 Receptor Agonists by Alessandro Boianelli, Pär Nordell, Joseph Earl, Jacqueline Naylor, David Hornigold, Rasmus Jansson Löfmark, Monika Sundqvist

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Metabolism and disposition of opicapone in the rat and metabolic enzymes phenotyping by Ana I. Loureiro, Carlos Fernandes‐Lopes, Maria João Bonifácio, Filipa Sousa, László E. Kiss, Patricio Soares‐da‐Silva

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PBPK Model of Coproporphyrin I: Evaluation of the Impact of SLCO1B1 Genotype, Ethnicity, and Sex on its Inter‐Individual Variability by Hiroyuki Takita, Shelby Barnett, Yueping Zhang, Karelle Ménochet, Hong Shen, Kayode Ogungbenro, Aleksandra Galetin

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Discovery of pulmonary fibrosis inhibitor targeting TGF-β RI in Polygonum cuspidatum by high resolution mass spectrometry with in silico strategy by Huarong Xu, Jiameng Qu, Jian Wang, Kefei Han, Qing Li, Wenchuan Bi, Ran Liu

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Very low monomethyl fumarate exposure via human milk: a case report-a contribution from the ConcePTION project by Martje Van Neste, Martje Van Neste, Nina Nauwelaerts, Michael Ceulemans, Michael Ceulemans, Michael Ceulemans, Benedikte Cuppers, Pieter Annaert, Pieter Annaert, Anne Smits, Anne Smits, Anne Smits, Karel Allegaert, Karel Allegaert, Karel Allegaert, Karel Allegaert

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PK/PD modeling links accelerated resolution of COVID‐19‐related clinical symptoms to SARS‐CoV‐2 viral load reduction in patients following treatment with Bamlanivimab alone or Baml... by C. Steven Ernest II, Jenny Y. Chien, Dipak R. Patel, Emmanuel Chigutsa

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In Vitro and Ex Vivo Investigation of the Antibacterial Effects of Methylene Blue against Methicillin-Resistant <i>Staphylococcus aureus</i> by Deniz Gazel, Mehmet Erinmez, Gönenç Çalışkantürk, Khandakar A. S. M. Saadat

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Cannabidiol Treatment for Refractory Epilepsies in Pediatrics by Umberto Raucci, Nicola Pietrafusa, Maria Chiara Paolino, Giovanni Di Nardo, Maria Pia Villa, Piero Pavone, Gianluca Terrin, Nicola Specchio, Pasquale Striano, Pasquale Parisi

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Inclusion complexes and self-assembled cyclodextrin aggregates for increasing the solubility of benzimidazoles by Leticia Norma Carpentieri Rodrigues, Anna Carollina Moraes Tavares, Beatriz Tavares Ferreira, Adriana Karla Cardoso Amorim Reis, Luciana Morita Katiki

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Assessing Bioequivalence of Antiepileptic Drugs: Are the Current Requirements too Permissive? by Camila F Rediguieri, Jorge L Zeredo

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Continuous high-dose infusion of doripenem in a pneumonia patient infected by carbapenem-resistant Pseudomonas aeruginosa: a case report by Kazutaka Oda, Hidenobu Kamohara, Tomomi Katanoda, Yumi Hashiguchi, Koji Iwamura, Kisato Nosaka, Hirofumi Jono, Hideyuki Saito

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Ibuprofen plasma concentration profile in deliberate ibuprofen overdose with circulatory depression treated with therapeutic plasma exchange: a case report by Stefanie Geith, Bertold Renner, Christian Rabe, Jochen Stenzel, Florian Eyer

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FcRn-enhancing mutations lead to increased and prolonged levels of the HIV CCR5-blocking monoclonal antibody leronlimab in the fetuses and newborns of pregnant rhesus macaques by Joanna Zikos, Gabriela M. Webb, Helen L. Wu, Jason S. Reed, Jennifer Watanabe, Jodie L. Usachenko, Ala M. Shaqra, Celia A. Schiffer, Koen K. A. Van Rompay, Jonah B. Sacha, Diogo M. Magnani

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Ghrelin transport across the blood-brain barrier can occur independently of the growth hormone secretagogue receptor by Elizabeth M. Rhea, Therese S. Salameh, Sarah Gray, Jingjing Niu, William A. Banks, Jenny Tong

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Improved Local Anesthesia at Inflamed Tissue Using the Association of Articaine and Copaiba Oil in Avocado Butter Nanostructured Lipid Carriers by Gustavo Henrique Rodrigues da Silva, Julia Borges Paes Lemes, Gabriela Geronimo, Fabíola Vieira de Carvalho, Talita Cesarim Mendonça, Kauê Franco Malange, Fernando Freitas de Lima, Márcia Cristina Breitkreitz, Carlos Amilcar Parada, Teresa Dalla Costa, Eneida de Paula

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Model Based Identification of Linezolid Exposure-toxicity Thresholds in Hospitalized Patients by Jie Fang, Xiao-Shan Zhang, Xiao-Shan Zhang, Chun-Hong Zhang, Zi-Ye Zhou, Lu Han, Ye-Xuan Wang, Xiao-Shuang He, Xiao-Lan Bian, Guan-Yang Lin, Zheng Jiao, Ying Dai, Xu-Ben Yu, Jing-Ye Pan

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