Search Results - "pharmacokinetics"

Alendronate modified mPEG-PLGA nano-micelle drug delivery system loaded with astragaloside has anti-osteoporotic effect in rats by Yanhai Xi, Weiheng Wang, Liang Ma, Ning Xu, Changgui Shi, Guohua Xu, Hailong He, Wenming Pan

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Hepatotoxicity of AKR1C3 Inhibitor BAY1128688: Findings from an Early Terminated Phase IIa Trial for the Treatment of Endometriosis by Jan Hilpert, Esther Groettrup-Wolfers, Hristiyan Kosturski, Laura Bennett, Catriona L. K. Barnes, Kerstin Gude, Isabella Gashaw, Stefanie Reif, Thomas Steger-Hartmann, Christian Scheerans, Alexander Solms, Antje Rottmann, Guangping Mao, Charles Chapron

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From Drug Discovery to Drug Approval: A Comprehensive Review of the Pharmacogenomics Status Quo with a Special Focus on Egypt by Fadya M. Elgarhy, Abdallah Borham, Noha Alziny, Khlood R. AbdElaal, Mahmoud Shuaib, Abobaker Salem Musaibah, Mohamed Ali Hussein, Anwar Abdelnaser

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Characterization of concurrent target suppression by JNJ-61178104, a bispecific antibody against human tumor necrosis factor and interleukin-17A by Songmao Zheng, Fang Shen, Brian Jones, Damien Fink, Brian Geist, Ivo Nnane, Zhao Zhou, Jeff Hall, Ravi Malaviya, Tatiana Ort, Weirong Wang

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Glutathione sulfotransferase inhibition activity of a self-fermented beverage, Kanji by Abida Latif, Khalid Hussain, Naureen Shehzadi, Muhammad Islam, Muhammad Tanveer Khan, Rukhsana Anwar, Humaira Majeed Khan, Nadeem Irfan Bukhari

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High-Throughput Screening and Molecular Dynamics Simulation of Natural Product-like Compounds against Alzheimer's Disease through Multitarget Approach by Danish Iqbal, Md Tabish Rehman, Abdulaziz Bin Dukhyil, Syed Mohd Danish Rizvi, Mohamed F. Al Ajmi, Bader Mohammed Alshehri, Saeed Banawas, M. Salman Khan, Wael Alturaiki, Mohammed Alsaweed

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Importance of Rare DPYD Genetic Polymorphisms for 5-Fluorouracil Therapy in the Japanese Population by Eiji Hishinuma, Eiji Hishinuma, Yoko Narita, Kai Obuchi, Akiko Ueda, Sakae Saito, Sakae Saito, Shu Tadaka, Kengo Kinoshita, Kengo Kinoshita, Kengo Kinoshita, Masamitsu Maekawa, Masamitsu Maekawa, Nariyasu Mano, Noriyasu Hirasawa, Noriyasu Hirasawa, Noriyasu Hirasawa, Masahiro Hiratsuka, Masahiro Hiratsuka, Masahiro Hiratsuka, Masahiro Hiratsuka

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The SGLT2 Inhibitor Empagliflozin Might Be a New Approach for the Prevention of Acute Kidney Injury by Chang Chu, Yong-Ping Lu, Lianghong Yin, Berthold Hocher

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Comparing Two Equations for Estimation of Kidney Function (Cock-croft-Gault and Glomerular Filtration Rate Assessment in Liver Disease) for Vancomycin Dosing in Adult Liver Transpl... by Yasaman Saee, Simin Dashti-Khavidaki, Zahra Ahmadinejad, Fereshteh Ghiasvand

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A Robust and Fast/Multiplex Pharmacogenetics Assay to Simultaneously Analyze 17 Clinically Relevant Genetic Polymorphisms in <i>CYP3A4</i>, <i>CYP3A5</i>, <i>CYP1A2</i>, <i>CYP2C9<... by Camille Tron, Régis Bouvet, Marie-Clémence Verdier, Fabien Lamoureux, Benjamin Hennart, Christèle Dubourg, Eric Bellissant, Marie-Dominique Galibert

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The use of extrapolation based on modeling and simulation to support high‐dose regimens of ceftaroline fosamil in pediatric patients with complicated skin and soft‐tissue infection... by Phylinda L.S. Chan, Lynn McFadyen, Andrea Quaye, Heidi Leister‐Tebbe, Victoria M. Hendrick, Jennifer Hammond, Susan Raber

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Acute liver failure in a term neonate after repeated paracetamol administration by Fabio Bucaretchi, Carla Borrasca Fernandes, Maira Migliari Branco, Eduardo Mello De Capitani, Stephen Hyslop, Jamil Pedro S. Caldas, Carolina Araujo Moreno, Gilda Porta

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Dichondra repens J.R.Forst. and G.Forst.: A Review of Its Traditional Uses, Chemistry, Pharmacology, Toxicology and Applications by Qi Yao, Ying Wang, Zhiyu Dong, Chencen Lai, Botao Chang, Qiuju Gong, Shuaijun Ren, Dongxue Sun, Jie Lu, Ying Gao

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The Effect of Intracellular Tacrolimus Exposure on Calcineurin Inhibition in Immediate- and Extended-Release Tacrolimus Formulations by Pere Fontova, Lisanne N. van Merendonk, Anna Vidal-Alabró, Raül Rigo-Bonnin, Gema Cerezo, Stefaan van Oevelen, Oriol Bestard, Edoardo Melilli, Nuria Montero, Ana Coloma, Anna Manonelles, Joan Torras, Josep M. Cruzado, Josep M. Grinyó, Helena Colom, Nuria Lloberas

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Potential of fenugreek (Trigonella foenum-graecum L.) metabolites as dental residual ridge resorption inhibitors through estrogen receptor signaling: In silico study by Ester Handayani Lodra, Muhammad Chair Effendi, Nur Permatasari, Respati Suryanto Dradjat

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Sex-related differences of lipid metabolism induced by triptolide: The possible role of the LXRα/SREBP-1 signaling pathway by Zhenzhou eJiang, Zhenzhou eJiang, Xiao eHuang, Shan eHuang, Hongli eGuo, Lu eWang, Xiaojiaoyang eLi, Xin eHuang, Xin eHuang, Tao eWang, Luyong eZhang, Luyong eZhang, Lixin eSun, Lixin eSun

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A first‐in‐human phase I study of SHR‐1906, a humanized monoclonal antibody against connective tissue growth factor, in healthy participants by Lin‐Lin Song, Hai‐Yan Zhou, Pan‐Pan Ye, Qian Li, Ke‐Guang Chen, Ye‐Hui Zhang, Fu‐Rong Zhao, Jin‐Yi Shi, Yuan Luo, Min Zhu, Jian‐Jun Zhang, Xin‐Mei Yang, Wei Zhao

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Bempedoic Acid, the First-in-Class Oral ATP Citrate Lyase Inhibitor with Hypocholesterolemic Activity: Clinical Pharmacology and Drug-Drug Interactions by Nicola Ferri, Elisa Colombo, Alberto Corsini

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Total Phenytoin concentration is not well correlated with active free drug in critically-ill head trauma patients by Kourosh Sadeghi, Farin Hadi, Arezoo Ahmadi, Hadi Hamishehkar, Mohammad-Taghi Beigmohammadi, Ata Mahmoodpoor, Mohammad Reza Rouini, Shirin Farhudi, Narjes Hendoui, Atabak Najafi, Mojtaba Mojtahedzadeh

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Amidated Pluronic Decorated Muco-Penetrating Self-Nano Emulsifying Drug Delivery System (SNEDDS) for Improved Anti-<i>Salmonella typhi</i> Potential by Rabia Arshad, Muhammad Salman Arshad, Tanveer A. Tabish, Syed Nisar Hussain Shah, Saira Afzal, Gul Shahnaz

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