Search Results - "pharmacokinetics"

Pharmacological effects of Berberine - A Chinese medicine, against xenobiotics toxicity by Annu Phogat, Jagjeet Singh, Vinay Malik

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Evaluation of Piperacillin/Sulbactam, Piperacillin/Tazobactam and Cefoperazone/Sulbactam Dosages in Gram-Negative Bacterial Bloodstream Infections by Monte Carlo Simulation by Xueting Wang, Luying Xiong, Wei Yu, Chen Huang, Jinru Ji, Chaoqun Ying, Zhiying Liu, Yunbo Chen, Yonghong Xiao

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Izokibep: Preclinical development and first-in-human study of a novel IL-17A neutralizing Affibody molecule in patients with plaque psoriasis by Susanne Klint, Joachim Feldwisch, Lindvi Gudmundsdotter, Karin Dillner Bergstedt, Elin Gunneriusson, Ingmarie Höidén Guthenberg, Anders Wennborg, Andrew C. Nyborg, Amol P. Kamboj, Paul M. Peloso, David Bejker, Fredrik Y. Frejd

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Effect of enzalutamide on PK of P‐gp and BCRP substrates in cancer patients: CYP450 induction may not always predict overall effect on transporters by Srinivasu Poondru, Vitalii Ghicavii, Reza Khosravan, Pooja Manchandani, Nakyo Heo, Selina Moy, Tomasz Wojtkowski, Melanie Patton, Gabriel P. Haas

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Interactions Between Ephedra sinica and Prunus armeniaca: From Stereoselectivity to Deamination as a Metabolic Detoxification Mechanism of Amygdalin by Yan Qin, Shanshan Wang, Qiuyu Wen, Qiuyu Wen, Quan Xia, Quan Xia, Sheng Wang, Guanjun Chen, Jiayin Sun, Chenlin Shen, Chenlin Shen, Shuai Song, Shuai Song

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A glyco-engineering approach for site-specific conjugation to Fab glycans by Maria L. Jaramillo, Traian Sulea, Yves Durocher, Mauro Acchione, Melissa J. Schur, Anna Robotham, John F. Kelly, Marie-France Goneau, Alma Robert, Yuneivy Cepero-Donates, Michel Gilbert

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Superior anti-neoplastic activities of triacontanol-PEG conjugate: synthesis, characterization and biological evaluations by Yimeng Zhou, Ning Li, Zhixia Qiu, Xiaoyu Lu, Min Fang, Xijing Chen, Lili Ren, Guangji Wang, Pingkai Ouyang

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Applications of linking PBPK and PD models to predict the impact of genotypic variability, formulation differences, differences in target binding capacity and target site drug conc... by Manoranjenni eChetty, Rachel eRose, Khaled eAbduljalil, Nikunjkumar ePatel, Gaohua eLu, Theresa eCain, Masoud eJamei, Amin eRostami-Hodjegan, Amin eRostami-Hodjegan

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Intestinally-restricted Janus Kinase inhibition: a potential approach to maximize the therapeutic index in inflammatory bowel disease therapy by David T. Beattie, M. Teresa Pulido-Rios, Fei Shen, Melissa Ho, Eva Situ, Pam R. Tsuruda, Patrick Brassil, Melanie Kleinschek, Sharath Hegde

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Cannabinoids and Pain: New Insights From Old Molecules by Sonja Vučković, Dragana Srebro, Katarina Savić Vujović, Čedomir Vučetić, Čedomir Vučetić, Milica Prostran

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High initial target blood concentration in target‐controlled infusion: A randomized controlled trial by Toshiaki Fujisawa, Shigeru Takuma, Yukie Nitta

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CYP2C9, CYPC19 and CYP2D6 gene profiles and gene susceptibility to drug response and toxicity in Turkish population by Merve Arici, Gül Özhan

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Randomized, placebo‐controlled, double‐blind phase I trial of co‐administered pyronaridine and piperaquine in healthy adults of sub‐Saharan origin by Andrea Kuemmerle, Denis Gossen, Annick Janin, Andrew Stokes, Nada Abla, Maja Szramowska, Ulrike Lorch, Myriam El Gaaloul, Isabelle Borghini‐Fuhrer, Stephan Chalon

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Oseltamivir phosphate for suspension is bioequivalent to TAMIFLU in healthy volunteers: a randomized, open-label clinical study by Ying Wang, Bangzhong Tang, Jing Xie, Xiaoqin Wang, Peng Ren, Guangmei Wu, Cuixia He, Minhui Zhu, Yue Su, Jiaxiang Ding, Yuanyuan Xu, Ling Fan, Qin Ge, Yuzhou Ding, Juan Zhu, Bingyan Liu, Rongfang Shan, Huan Zhou

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Optimizing pharmacotherapy in elderly patients: the role of pharmacists by Lee JK, Alshehri S, Kutbi HI, Martin JR

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β-Cell Autophagy Pathway and Endoplasmic Reticulum Stress Regulating-Role of Liposomal Curcumin in Experimental Diabetes Mellitus: A Molecular and Morphometric Study by Safaa I. Khater, Mohamed F. Dowidar, Aya E. Abdel-Aziz, Tarek Khamis, Naief Dahran, Leena S. Alqahtani, Mohamed M. M. Metwally, Al-Sa, Mohammed Alsieni, Manal E. Alosaimi, Maram H. Abduljabbar, Amany Abdel-Rahman Mohamed

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Bioanalysis of the Ex Vivo Labile PACE4 Inhibitory Peptide Ac-[<span style="font-variant: small-caps">d-</span>Leu]LLLRVK-Amba in Whole Blood Using Ultra-Performance Liquid Chromat... by Max Sauter, Jonas Haag, Cindy Bay, Florian Leuschner, Walter E. Haefeli, Tim Christian Kuhn, Jürgen Burhenne

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Inhalation delivery dramatically improves the efficacy of topotecan for the treatment of local and distant lung cancer by Philip J. Kuehl, Christin M. Yingling, Devon Dubose, Michael Burke, David A. Revelli, Wenshu Chen, Wendy W. Dye, Steven A. Belinsky, Mathewos Tessema

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Scope and relevance of a pulmonary biopharmaceutical classification system AAPS/FDA/USP Workshop March 16-17th, 2015 in Baltimore, MD by Jayne E. Hastedt, Per Bäckman, Andrew R. Clark, William Doub, Anthony Hickey, Guenther Hochhaus, Phil J. Kuehl, Claus-Michael Lehr, Peter Mauser, Jason McConville, Ralph Niven, Masahiro Sakagimi, Jeffry G. Weers

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Enhancement of oral bioavailability and anti-Parkinsonian efficacy of resveratrol through a nanocrystal formulation by Sha Xiong, Wei Liu, Yile Zhou, Yousheng Mo, Yao Liu, Xiaojia Chen, Huafeng Pan, Dongsheng Yuan, Qi Wang, Tongkai Chen

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