Search Results - "pharmacokinetics"

Co-Amorphous Formation of Simvastatin-Ezetimibe: Enhanced Physical Stability, Bioavailability and Cholesterol-Lowering Effects in LDLr−/−Mice by Shamuha Bahetibieke, Sakib M. Moinuddin, Asiya Baiyisaiti, Xiaoang Liu, Jie Zhang, Guomin Liu, Qin Shi, Ankang Peng, Jun Tao, Chang Di, Ting Cai, Rong Qi

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A randomised, controlled, two-Centre open-label study in healthy Japanese subjects to evaluate the effect on biomarkers of exposure of switching from a conventional cigarette to a... by Nathan Gale, Mike McEwan, Alison C. Eldridge, Neil Sherwood, Edward Bowen, Simon McDermott, Emma Holmes, Andrew Hedge, Stuart Hossack, Oscar M. Camacho, Graham Errington, John McAughey, James Murphy, Chuan Liu, Christopher J. Proctor, Ian M. Fearon

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Novel ⁶⁸Ga-Labeled Pyridine-Based Fibroblast Activation Protein-Targeted Tracers with High Tumor-to-Background Contrast by Arsyangela Verena, Hsiou-Ting Kuo, Helen Merkens, Jutta Zeisler, Shreya Bendre, Antonio A. W. L. Wong, François Bénard, Kuo-Shyan Lin

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First‐in‐human study of JNJ‐67571244, a CD33 × CD3 bispecific antibody, in relapsed/refractory acute myeloid leukemia and myelodysplastic syndrome by Rupa Narayan, Ana Alfonso Piérola, William B. Donnellan, Antonieta Molero Yordi, Maher Abdul‐Hay, Uwe Platzbecker, Marion Subklewe, Tapan Mahendra Kadia, Juan Manuel Alonso‐Domínguez, James McCloskey, Kathryn Bradford, Martin Curtis, Nikki Daskalakis, Christina Guttke, Karim Safer, Brett Hiebert, Joseph Murphy, Xiang Li, Ken Duchin, Daniel Esteban

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Pharmacology and immuno-virologic efficacy of once-a-day HAART in African HIV-infected children: ANRS 12103 phase II trial by Boubacar Nacro, Emmanuelle Zoure, Hervé Hien, Hassane Tamboura, François Rouet, Adama Ouiminga, Ali Drabo, Souleymane Yameogo, Alain Hien, Hélène Peyriere, Olivier Mathieu, Deborah Hirt, Jean-Marc Treluyer, Joëlle Nicolas, Vincent Foulongne, Michel Segondy, Philippe van de Perre, Serge Diagbouga, Philippe Msellati

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The fallacy of enzymatic hydrolysis for the determination of bioactive curcumin in plasma samples as an indication of bioavailability: a comparative study by Sidney J. Stohs, C. Y. O. Chen, Harry G. Preuss, Sidhartha D. Ray, Luke R. Bucci, Jin Ji, Kevin J. Ruff

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Latamoxef for Neonates With Early-Onset Neonatal Sepsis: A Study Protocol for a Randomized Controlled Trial by Hui Qi, Yue-E Wu, Ya-Li Liu, Chen Kou, Ze-Ming Wang, Xiao-Xia Peng, Liang Chen, Hong Cui, Ya-Juan Wang, Jie-Qiong Li, Wei Zhao, Wei Zhao, A-Dong Shen, A-Dong Shen

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First‐in‐human study of JNJ‐63709178, a CD123/CD3 targeting antibody, in relapsed/refractory acute myeloid leukemia by Michael Boyiadzis, Pinkal Desai, Nikki Daskalakis, William Donnellan, Lucille Ferrante, Jenna D. Goldberg, Michael R. Grunwald, Christina Guttke, Xiang Li, Jose Antonio Perez‐Simon, Olga Salamero, Trevor Tucker, Xiaoying Xu, Jay Yang, Naveen Pemmaraju, Juan Manuel Alonso‐Dominguez

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A randomized trial comparing the pharmacology of magnesium sulfate when used to treat severe preeclampsia with serial intravenous boluses versus a continuous intravenous infusion by Thomas Easterling, Mary Hebert, Hillary Bracken, Emad Darwish, Mohamed Cherine Ramadan, Salwa Shaarawy, Dyanna Charles, Tamer Abdel-Aziz, Ahmed Shokry Nasr, Sherif Mohamed Safwal, Beverly Winikoff

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The effect of pregnancy-related hormones on hepatic transporters: studies with premenopausal human hepatocytes by Jhohann Richard de Lima Benzi, Yik Pui Tsang, Jashvant D. Unadkat

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INFLUENCE OF CHRONOTHERAPY WITH DIFFERENT ANTIHYPERTENSIVE DRUGS ON CIRCADIAN BLOOD PRESSURE PATTERN by V. M. Gorbunov, E. Yu. Fedorova, A. D. Deev, O. Yu. Isaikina, V. G. Belolipetskaya, E. A. Zhabina

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Benzoquinoline Derivatives: A Straightforward and Efficient Route to Antibacterial and Antifungal Agents by Vasilichia Antoci, Liliana Oniciuc, Dorina Amariucai-Mantu, Costel Moldoveanu, Violeta Mangalagiu, Andreea Madalina Amarandei, Claudiu N. Lungu, Simona Dunca, Ionel I. Mangalagiu, Gheorghita Zbancioc

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Toward Stability Enhancement of NTS₁R-Targeted Radioligands: Structural Interventions on [^99mTc]Tc-DT1 by Panagiotis Kanellopoulos, Berthold A. Nock, Eric P. Krenning, Theodosia Maina

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Atypical Pharmacodynamic Properties and Metabolic Profile of the Abused Synthetic Cannabinoid AB-PINACA: Potential Contribution to Pronounced Adverse Effects Relative to Δ9-THC by Rachel D. Hutchison, Benjamin M. Ford, Lirit N. Franks, Catheryn D. Wilson, Azure L. Yarbrough, Ryoichi Fujiwara, Mark K. Su, Denise Fernandez, Laura P. James, Jeffery H. Moran, Amy L. Patton, William E. Fantegrossi, Anna Radominska-Pandya, Paul L. Prather

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Bone targeting compounds for radiotherapy and imaging: *Me(III)-DOTA conjugates of bisphosphonic acid, pamidronic acid and zoledronic acid by M. Meckel, R. Bergmann, M. Miederer, F. Roesch

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Analgesic Activity of 5-Acetamido-2-Hydroxy Benzoic Acid Derivatives and an In-Vivo and In-Silico Analysis of Their Target Interactions by Cleydson B. R. Santos, Cleison C. Lobato, Sirlene S. B. Ota, Rai C. Silva, Renata C. V. S. Bittencourt, Jofre J. S. Freitas, Elenilze F. B. Ferreira, Marília B. Ferreira, Renata C. Silva, Anderson B. De Lima, Joaquín M. Campos, Rosivaldo S. Borges, José A. H. M. Bittencourt

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Differential Preincubation Effects of Nicardipine on OATP1B1- and OATP1B3-Mediated Transport in the Presence and Absence of Protein: Implications in Assessing OATP1B1- and OATP1B3-... by Ruhul Kayesh, Vishakha Tambe, Chao Xu, Wei Yue

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Strontium Sulfite: A New pH-Responsive Inorganic Nanocarrier to Deliver Therapeutic siRNAs to Cancer Cells by Md. Emranul Karim, Jayalaxmi Shetty, Rowshan Ara Islam, Ahsanul Kaiser, Athirah Bakhtiar, Ezharul Hoque Chowdhury

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Long-Lasting Exendin-4-Coated Gold Nanoparticles: Synthesis and In Vivo Evaluation of Hypoglycemic Activity by Reeju Amatya, Amala Joseph, Gu Seob Roh, Yassmine Benmokadem, Kyoung Ah Min, Meong Cheol Shin

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Bioaccumulation and biotransformation of simvastatin in probiotic bacteria: A step towards better understanding of drug-bile acids-microbiome interactions by Maja Đanić, Nebojša Pavlović, Slavica Lazarević, Bojan Stanimirov, Saša Vukmirović, Hani Al-Salami, Hani Al-Salami, Armin Mooranian, Armin Mooranian, Momir Mikov

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