Search Results - "pharmacokinetics"

Successful High-Dosage Monotherapy of Tigecycline in a Multidrug-Resistant <i>Klebsiella pneumoniae</i> Pneumonia-Septicemia Model in Rats by Hessel Van der Weide, Marian T. Ten Kate, Denise M. C. Vermeulen-de Jongh, Aart Van der Meijden, Rixt A. Wijma, Stefan A. Boers, Mireille Van Westreenen, John P. Hays, Wil H. F. Goessens, Irma A. J. M. Bakker-Woudenberg

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Neutrophil elastase as a versatile cleavage enzyme for activation of αvβ3 integrin-targeted small molecule drug conjugates with different payload classes in the tumor microenvironm... by Anne-Sophie Rebstock, Mareike Wiedmann, Beatrix Stelte-Ludwig, Harvey Wong, Amy J. Johnson, Raquel Izumi, Ahmed Hamdy, Hans-Georg Lerchen

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Assessing acute systemic effects of an inhaled drug with serial echocardiography: a placebo-controlled comparison of inhaled and intravenous dihydroergotamine by Noveck RJ, Douglas PS, Chow SC, Mangum B, Kori S, Kellerman DJ

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Effect of Betanin, the Major Pigment of Red Beetroot (<i>Beta vulgaris</i> L.), on the Activity of Recombinant Human Cytochrome P450 Enzymes by Sung Ho Lim, Seoungpyo Bae, Ho Seon Lee, Hyo-Kyung Han, Chang-Ik Choi

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Comparison of the Blood-Brain Barrier Transport and Vulnerability to P-Glycoprotein-Mediated Drug-Drug Interaction of Domperidone versus Metoclopramide Assessed Using In Vitro Assa... by Louise Breuil, Sébastien Goutal, Solène Marie, Antonio Del Vecchio, Davide Audisio, Amélie Soyer, Maud Goislard, Wadad Saba, Nicolas Tournier, Fabien Caillé

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Serum infliximab levels and clinical response in hidradenitis suppurativa by Erwin Benassaia, Jean‐David Bouaziz, Marie Jachiet, Florence Cordoliani, Anne Saussine, Clemence Lepelletier, Lauriane Goldwirt, Charles Cassius, Adèle deMasson, Martine Bagot, Hervé Bachelez, Florence Assan

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Acetazolamide and human carbonic anhydrases: retrospect, review and discussion of an intimate relationship by Dimitrios Tsikas

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Combinative effects of akarkara root-derived metabolites on anti-inflammatory and anti-alzheimer key enzymes: integrating bioassay-guided fractionation, GC-MS analysis, and in sili... by Rana M. Ibrahim, Passent M. Abdel-Baki, Ghada F. Elmasry, Ahmed A. El-Rashedy, Nariman E. Mahdy

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Variability of efavirenz plasma concentrations among pediatric HIV patients treated with efavirenz based combination antiretroviral therapy in Dar es Salaam, Tanzania by Selemani Saidi Sungi, Eliford Ngaimisi, Nzovu Ulenga, Philip Sasi, Sabina Mugusi

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PBPK-based translation from preclinical species to humans for the full-size IgG therapeutic efalizumab by Maria Franz, Ravi Kumar Jairam, Lars Kuepfer, Nina Hanke

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Gene Expression and Protein Abundance of Hepatic Drug Metabolizing Enzymes in Liver Pathology by Marek Drozdzik, Joanna Lapczuk-Romanska, Christoph Wenzel, Sylwia Szelag-Pieniek, Mariola Post, Łukasz Skalski, Mateusz Kurzawski, Stefan Oswald

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MIJ821 (onfasprodil) in healthy volunteers: First‐in‐human, randomized, placebo‐controlled study (single ascending dose and repeated intravenous dose) by Baltazar Gomez‐Mancilla, Jeffrey A. Levy, Subramanian Ganesan, Thomas Faller, Gil Issachar, Ziv Peremen, Offir Laufer, Revital Shani‐Hershkovich, Kostas Biliouris, Ela Walker, Mark P. Healy, Oleksandr Sverdlov, Sachin Desai, S. Nassir Ghaemi, Jang‐Ho Cha, Y. Gopi Shanker

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In vivo study of doxorubicin-loaded cell-penetrating peptide-modified pH-sensitive liposomes: biocompatibility, bio-distribution, and pharmacodynamics in BALB/c nude mice bearing h... by Ding Y, Cui W, Sun D, Wang GL, Hei Y, Meng S, Chen JH, Xie Y, Wang ZQ

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Determination of the Cut-off Value for Imatinib Plasma Levels Linked to Occurrence of Bone Pain in CML Patients by Hamza MS, Shouman SA, Abdelfattah R, Moussa HS, Omran MM

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Oral calcitonin by Hamdy RC, Daley DN

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A clinical trial of enteral Levetiracetam for acute seizures in pediatric cerebral malaria by Gretchen L. Birbeck, Susan T. Herman, Edmund V. Capparelli, Fraction K. Dzinjalamala, Samah G. Abdel Baki, Macpherson Mallewa, Neema M. Toto, Douglas G. Postels, Joseph C. Gardiner, Terrie E. Taylor, Karl B. Seydel

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Elimination of plasma soluble antigen in cynomolgus monkeys by combining pH-dependent antigen binding and novel Fc engineering by Yuji Hori, Ken Ohmine, Hitoshi Katada, Yuki Noguchi, Kazuki Sato, Takeru Nambu, Lam Runyi Adeline, Gan Siok Wan, Kenta Haraya, Kazuhisa Ozeki, Masahiko Nanami, Tatsuhiko Tachibana, Zenjiro Sampei, Taichi Kuramochi, Junichi Nezu, Kunihiro Hattori, Tomoyuki Igawa

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Study of Linearization of Hill Dose-Effect Curve with Metabolic Velocity Instead of Drug Concentration by Run-Nan LIU, Yu TANG, Ping-An LIU, Wen-Long LIU, Qi-Meng FAN, Si-Yang CHEN, Peng HE, Hai-Ying LI, Fu-Yuan HE, Kai-Wen DENG

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Efficacy of Sub-Tenon Micro-Perfusion of Cyclophosphamide in Rabbits with Severe Ocular Inflammation by Zhao L, Peng M, Lin W, Tan Q, Khan MA, Lin D

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Eugenol-Rich Essential Oils from Flower Buds and Leaves of <i>Syzygium aromaticum</i> Show Antifungal Activity against <i>Candida</i> and <i>Cryptococcus</i> Species by Evariste Josué Momo, François Nguimatsia, Laure Ateufouet Ngouango, Paul Keilah Lunga, Boniface Pone Kamdem, Pierre Michel Jazet Dongmo

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