Search Results - "pharmacokinetics"

Influence of Cytochrome P450 2C19 Genotype on Helicobacter pylori Proton Pump Inhibitor-Amoxicillin-Clarithromycin Eradication Therapy: A Meta-Analysis by Yuko Morino, Mitsushige Sugimoto, Naoyoshi Nagata, Ryota Niikiura, Eri Iwata, Mariko Hamada, Yusuke Kawai, Tatsuhiro Fujimiya, Hironori Takeuchi, Sakae Unezaki, Takashi Kawai

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Hepatic Cytochrome P450 Abundance and Activity in the Developing and Adult Göttingen Minipig: Pivotal Data for PBPK Modeling by Laura Buyssens, Laura De Clerck, Wim Schelstraete, Maarten Dhaenens, Dieter Deforce, Miriam Ayuso, Chris Van Ginneken, Steven Van Cruchten

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Effervescent N-Acetylcysteine Tablets versus Oral Solution N-Acetylcysteine in Fasting Healthy Adults: An Open-Label, Randomized, Single-Dose, Crossover, Relative Bioavailability S... by Spencer C. Greene, MD, FACEP, FACMT, Patrick K. Noonan, PhD, Carlos Sanabria, MD, FACP, W. Frank Peacock, MD, FACEP, FACC

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Elevation of tacrolimus concentration after administration of methotrexate for treatment of graft-versus-host disease in pediatric patients received allogeneic hematopoietic stem c... by Chiaki Inoue, Takehito Yamamoto, Hiroshi Miyata, Hiroshi Suzuki, Tappei Takada

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Bioequivalence Study of 100-mg Cilostazol Tablets in Healthy Thai Adult Volunteers by Somruedee Chatsiricharoenkul, MD, Yanisorn Nanchaipruek, MD, Patcharaporn Manopinives, MSc (Pharm), Suparat Atakulreka, MPharm, Suvimol Niyomnaitham, MD, PhD

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A prospective, observational study comparing the PK/PD relationships of generic Meropenem (Mercide®) to the innovator brand in critically ill patients by Mer M, Snyman JR, van Rensburg CEJ, van Tonder JJ, Laurens I

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Silver nanoparticles from Saudi and syrian black cumin seed extracts: Green synthesis, ADME, toxicity, comparative research, and biological appraisal by Mohammad Rashid, Md Tanwir Athar, Mohammed Abdelmageed, Mohammed Hilal M Al-Harbi, Asif Husain, Dheeraj Bisht, Rajeshwar Kamal Kant Arya

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Rejuveinix Shows a Favorable Clinical Safety Profile in Human Subjects and Exhibits Potent Preclinical Protective Activity in the Lipopolysaccharide-Galactosamine Mouse Model of Ac... by Fatih M. Uckun, Fatih M. Uckun, James Carlson, Cemal Orhan, Joy Powell, Natalie M. Pizzimenti, Hendrik van Wyk, Ibrahim H. Ozercan, Michael Volk, Kazim Sahin

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In vitro and in vivo evaluation of a tetrazine-conjugated poly-L-lysine effector molecule labeled with astatine-211 by Chiara Timperanza, Holger Jensen, Ellinor Hansson, Tom Bäck, Sture Lindegren, Emma Aneheim

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Identifying non-nucleoside inhibitors of RNA-dependent RNA-polymerase of SARS-CoV-2 through per-residue energy decomposition-based pharmacophore modeling, molecular docking, and mo... by Shahkaar Aziz, Muhammad Waqas, Tapan Kumar Mohanta, Sobia Ahsan Halim, Aqib Iqbal, Amjad Ali, Asaad Khalid, Ashraf N. Abdalla, Ajmal Khan, Ahmed Al-Harrasi

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Inhibitory Effect of AB-PINACA, Indazole Carboxamide Synthetic Cannabinoid, on Human Major Drug-Metabolizing Enzymes and Transporters by Eun Jeong Park, Ria Park, Ji-Hyeon Jeon, Yong-Yeon Cho, Joo Young Lee, Han Chang Kang, Im-Sook Song, Hye Suk Lee

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Combination of sofosbuvir and daclatasvir in the treatment of genotype 3 chronic hepatitis C virus infection in patients on maintenance hemodialysis by Sperl J, Frankova S, Kreidlova M, Merta D, Tothova M, Spicak J

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Model Informed Dosing Regimen and Phase I Results of the Anti‐PD‐1 Antibody Budigalimab (ABBV‐181) by John Powderly, Alexander Spira, Shunsuke Kondo, Toshihiko Doi, Jason J. Luke, Drew Rasco, Bo Gao, Minna Tanner, Philippe A. Cassier, Anas Gazzah, Antoine Italiano, Diego Tosi, Daniel E. Afar, Apurvasena Parikh, Benjamin Engelhardt, Stefan Englert, Stacie L. Lambert, Sreeneeranj Kasichayanula, Sven Mensing, Rajeev Menon, Gregory Vosganian, Anthony Tolcher

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Toxicity Associated with Immune Checkpoint Inhibitors: Analysis of Immune-Related Adverse Events with a Pembrolizumab Biosimilar (Pembroria) by M. Yu. Fedyanin, A. V. Snegovoy, V. V. Breder, Yu. N. Linkova, A. V. Zinkina-Orikhan, S. B. Setkina, S. N. Fogt, V. S. Chistiakov, N. A. Kravtsova

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Inhibition of Caffeine Metabolism by Apiaceous and Rutaceae Families of Plant Products in Humans: In Vivo and In Vitro Studies by Zeyad Alehaideb, Zeyad Alehaideb, Zeyad Alehaideb, Mohamed Sheriffdeen, Francis C. P. Law

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Effects of 3,4-Methylenedioxymethamphetamine on Conditioned Fear Extinction and Retention in a Crossover Study in Healthy Subjects by Patrick Vizeli, Patrick Vizeli, Patrick Vizeli, Isabelle Straumann, Isabelle Straumann, Urs Duthaler, Urs Duthaler, Nimmy Varghese, Nimmy Varghese, Anne Eckert, Anne Eckert, Martin P. Paulus, Victoria Risbrough, Victoria Risbrough, Matthias E. Liechti, Matthias E. Liechti

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Organic Anion Transporting Polypeptide 2B1 (OATP2B1) Genetic Variants: In Vitro Functional Characterization and Association With Circulating Concentrations of Endogenous Substrates by Samantha Medwid, Samantha Medwid, Hayley R. Price, Daniel P. Taylor, Jaymie Mailloux, Jaymie Mailloux, Ute I. Schwarz, Ute I. Schwarz, Richard B. Kim, Richard B. Kim, Richard B. Kim, Rommel G. Tirona, Rommel G. Tirona

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Complexes of Ibuprofen Thiazolidin-4-One Derivatives with β-Cyclodextrin: Characterization and In Vivo Release Profile and Biological Evaluation by Ioana Mirela Vasincu, Maria Apotrosoaei, Florentina Lupascu, Andreea-Teodora Iacob, Simona-Eliza Giusca, Irina-Draga Caruntu, Narcisa-Laura Marangoci, Anca Roxana Petrovici, Gabriela Dumitrita Stanciu, Bogdan-Ionel Tamba, Bianca-Stefania Profire, Alin-Viorel Focsa, Mariana Pinteala, Lenuta Profire

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Decorating sdAbs with Chelators: Effect of Conjugation on Biodistribution and Functionality by Henri Baudhuin, Janik Puttemans, Heleen Hanssens, Philippe Vanwolleghem, Sophie Hernot, Geert Raes, Catarina Xavier, Tony Lahoutte, Pieterjan Debie

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Brivaracetam: review of its pharmacology and potential use as adjunctive therapy in patients with partial onset seizures by Mumoli L, Palleria C, Gasparini S, Citraro R, Labate A, Ferlazzo E, Gambardella A, De Sarro G, Russo E

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