Search Results - "pharmacokinetics"

Quantification of the Therapeutic Antibody Ocrelizumab in Mouse Brain Interstitial Fluid Using Cerebral Open Flow Microperfusion and Simultaneous Monitoring of the Blood-Brain Barr... by Thomas Altendorfer-Kroath, Joanna Hummer, Denise Kollmann, Beate Boulgaropoulos, Reingard Raml, Thomas Birngruber

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Subcutaneous implants for long-acting drug therapy in laboratory animals may generate unintended drug reservoirs by Michael Guarnieri, Betty M Tyler, Louis DeTolla, Ming Zhao, Barry Kobrin

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Discovery of novel 2,4-diarylaminopyrimidine hydrazone derivatives as potent anti-thyroid cancer agents capable of inhibiting FAK by Hongting Li, Mei-Qi Jia, Zhao-Long Qin, Changliang Lu, Weili Chu, Ze Zhang, Jinbo Niu, Jian Song, Sai-Yang Zhang, Lijun Fu

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Reduction-Responsive Stearyl Alcohol-Cabazitaxel Prodrug Nanoassemblies for Cancer Chemotherapy by Yuting Liu, Xinhui Wang, Zhe Wang, Rui Liao, Qian Qiu, Yuequan Wang, Cong Luo

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In Vitro and In Vivo Evaluation of Oral Controlled Release Formulation of BCS Class I Drug Using Polymer Matrix System by Mosab Arafat, Muhammad Sarfraz, Mohammad F. Bostanudin, Anna Esmaeil, Aisha Salam, Salahdein AbuRuz

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The Combined Anti-Tumor Efficacy of Bioactive Hydroxyapatite Nanoparticles Loaded with Altretamine by Yahia Alghazwani, Krishnaraju Venkatesan, Kousalya Prabahar, Mohamed El-Sherbiny, Nehal Elsherbiny, Mona Qushawy

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l-Carnitine conjugated chitosan-stearic acid polymeric micelles for improving the oral bioavailability of paclitaxel by Tan Yang, Jianfang Feng, Qian Zhang, Wei Wu, Hailan Mo, Lanzhen Huang, Wei Zhang

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Defining desirable natural product derived anticancer drug space: optimization of molecular physicochemical properties and ADMET attributes by Deepika Singh

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1,3,4-Oxadiazole-naphthalene hybrids as potential VEGFR-2 inhibitors: design, synthesis, antiproliferative activity, apoptotic effect, and in silico studies by Mohamed Hagras, Marwa A. Saleh, Rogy R. Ezz Eldin, Abdelrahman A. Abuelkhir, Emad Gamil Khidr, Ahmed A. El-Husseiny, Hesham A. El-Mahdy, Eslam B. Elkaeed, Ibrahim H. Eissa

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Antioxidant, Anti-Inflammatory, and Anticarcinogenic Efficacy of an Ayurvedic Formulation: Amritotharanam Kashyam by Lakshmi Sundaram Raman, Anitha Shanmuganathan, Sangeeta Chandrashekar, Prabhu Kaliyaperumal, Elumalai Perumal, Ram Krishna Rao Mudiganti, K. T. Nachammai, Langeswaran Kulanthaivel, Gowtham Kumar Subbaraj, Kirubhanand Chandrasekaran, Bharat Ramrao Sontakke, Senthilkumar Subramanian

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Clinically important drug interactions with opioid and non-opioid analgesics by Vezmar-Kovačević Sandra, Vučićević Katarina, Topić-Vučenović Valentina, Rajkovača Zvezdana, Miljković Branislava

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Phytochemical Characterization and In Vitro and In Silico Biological Studies from Ferns of Genus <i>Blechnum</i> (Blechnaceae, Polypodiales) by Alfredo Torres-Benítez, José Erick Ortega-Valencia, Mathias Flores-González, Marta Sánchez, Mario J. Simirgiotis, María Pilar Gómez-Serranillos

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Assessment of Finite and Infinite Dose In Vitro Experiments in Transdermal Drug Delivery by Luisa Coderch, Ilaria Collini, Victor Carrer, Clara Barba, Cristina Alonso

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Design, Synthesis, anticancer evaluation and in silico studies of 2,4,6-trimethoxychalcone derivatives by Tong Li, Weiwei Li, Xianjing Yang, Gong Chen, Xiaobao Jin, Weiqiang Chen, Lianbao Ye

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Comprehensive Assessment of the Stability of Selected Coxibs in Variable Environmental Conditions along with the Assessment of Their Potential Hepatotoxicity by Paweł Gumułka, Łukasz Pecio, Paweł Żmudzki, Krzesimir Ciura, Krystyna Skalicka-Woźniak, Monika Dąbrowska, Małgorzata Starek

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Hyaluronidase Inhibitor-Incorporated Cross-Linked Hyaluronic Acid Hydrogels for Subcutaneous Injection by Min-Hwan Kim, Ju-Hwan Park, Duy-Thuc Nguyen, Sungyun Kim, Da In Jeong, Hyun-Jong Cho, Dae-Duk Kim

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Biased computation of probability of target attainment for antimicrobial drugs by Pierre‐Louis Toutain, Peggy Gandia, Ludovic Pelligand, Aude A. Ferran, Peter Lees, Alain Bousquet‐Mélou, Didier Concordet

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An Engineered IFNγ-Antibody Fusion Protein with Improved Tumor-Homing Properties by Cesare Di Nitto, Ettore Gilardoni, Jacqueline Mock, Lisa Nadal, Tobias Weiss, Michael Weller, Frauke Seehusen, Chiara Libbra, Emanuele Puca, Dario Neri, Roberto De Luca

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A convolution‐based in vitro‐in vivo correlation model for methylphenidate hydrochloride delayed‐release and extended‐release capsule by Pawan Kumar Gupta, Bev Incledon, Jogarao V. S. Gobburu, Roberto Gomeni

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2-Thiopyrimidine/chalcone hybrids: design, synthesis, ADMET prediction, and anticancer evaluation as STAT3/STAT5a inhibitors by Phoebe F. Lamie, John N. Philoppes

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