Search Results - "pharmacokinetics"

In silico evaluation of Vitis amurensis Rupr. Polyphenol compounds for their inhibition potency against COVID-19 main enzymes Mpro and RdRp by Imen Souid, Atef Korchef, Safouan Souid

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Pharmacometrics enhanced Bayesian borrowing approach to improve clinical trial efficiency: Case of empagliflozin in type 2 diabetes by Lucie Fayette, Martin Oliver Sailer, Alejandro Perez‐Pitarch

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Darovasertib, a novel treatment for metastatic uveal melanoma by Lei Cao, Shuzhen Chen, Rainie Sun, Rainie Sun, Charles R. Ashby, Liuya Wei, Zoufang Huang, Zhe-Sheng Chen

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Tutorial for $DESIGN in NONMEM: Clinical trial evaluation and optimization by Robert J. Bauer, Andrew C. Hooker, France Mentre

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Influence of YES1 Kinase and Tyrosine Phosphorylation on the Activity of OCT1 by Muhammad Erfan Uddin, Dominique A. Garrison, Kyeongmin Kim, Yan Jin, Eric D. Eisenmann, Kevin M. Huang, Alice A. Gibson, Zeping Hu, Alex Sparreboom, Shuiying Hu

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Design, synthesis, molecular modeling, and biological evaluation of acrylamide derivatives as potent inhibitors of human dihydroorotate dehydrogenase for the treatment of rheumatoi... by Fanxun Zeng, Shiliang Li, Guantian Yang, Yating Luo, Tiantian Qi, Yingfan Liang, Tingyuan Yang, Letian Zhang, Rui Wang, Lili Zhu, Honglin Li, Xiaoyong Xu

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Simvastatin nanoliposome induces myocardial and hepatic toxicities due to its absorption enhancement in mice by Nuerbiye Tuerdi, Gulinigaer Anwaier, Xing Zhang, Shu Liu, Wanli Shen, Wen Liu, Qiang Shen, Rong Qi

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Synthesis and biological evaluation of pyrrolidine-based T-type calcium channel inhibitors for the treatment of neuropathic pain by Hak Kyun Yang, Woo Seung Son, Keon Seung Lim, Gun Hee Kim, Eun Jeong Lim, Changdev G. Gadhe, Jae Yeol Lee, Kyu-Sung Jeong, Sang Min Lim, Ae Nim Pae

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Polyphenols in Almond Skins after Blanching Modulate Plasma Biomarkers of Oxidative Stress in Healthy Humans by C.-Y. Oliver Chen, Paul E. Milbury, Jeffrey B. Blumberg

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Liposomes for systematic delivery of vancomycin hydrochloride to decrease nephrotoxicity: Characterization and evaluation by Junli Liu, Zhonglan Wang, Fubing Li, Jinhua Gao, Longmei Wang, Guihua Huang

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Compartmental and COMSOL Multiphysics 3D Modeling of Drug Diffusion to the Vitreous Following the Administration of a Sustained-Release Drug Delivery System by Emily Dosmar, Gabrielle Vuotto, Xingqi Su, Emily Roberts, Abigail Lannoy, Garet J. Bailey, William F. Mieler, Jennifer J. Kang-Mieler

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Effect of 5-Oxo-2-Pyrrolidinecarboxylic Acid (PCA) as a New Topically Applied Agent for Dry Eye Syndrome Treatment by Silvia Tampucci, Daniela Monti, Susi Burgalassi, Eleonora Terreni, Erica Zucchetti, Filippo Baldacci, Patrizia Chetoni

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Design of Marine Cyclodepsipeptide Analogues Targeting <i>Candida albicans</i> Efflux Pump CaCdr1p by Ricardo Ribeiro, Sara Fortes, Lia Costa, Andreia Palmeira, Eugénia Pinto, Emília Sousa, Carla Fernandes

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Ginsenoside Rg1 protects against transient focal cerebral ischemic injury and suppresses its systemic metabolic changes in cerabral injury rats by Mingbao Lin, Wei Sun, Wan Gong, Yasi Ding, Yuanyan Zhuang, Qi Hou

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Changing the drug development and therapeutic paradigm with biologic drug combinations and bispecifics: How to choose between these two approaches? by Songmao Zheng, Rodney Prell, Jennifer Sheng, Yow‐Ming Wang, Lora Hamuro

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Obstructive Sleep Apnea and Acute Lower Respiratory Tract Infections: A Narrative Literature Review by Marko Nemet, Marija Vukoja

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Nanoparticles from Gantrez-based conjugates for the oral delivery of camptothecin by Judit Huarte, Socorro Espuelas, Cristina Martínez-Oharriz, Juan M. Irache

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Prospects and Challenges of Phospholipid-Based Prodrugs by Milica Markovic, Shimon Ben-Shabat, Shahar Keinan, Aaron Aponick, Ellen M. Zimmermann, Arik Dahan

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DEVELOPMENT AND EVALUATION OF CONTROLLED RELEASE FORMULATION OF LAMIVUDINE BASED ON MICROPOROUS OSMOTIC TABLET TECHNOLOGY USING FRUCTOSE AS OSMOGEN by Chinmayakeshari sahoo, Surepalli Ram Mohan Rao, Muvvala Sudhakar

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No dose adjustment of metformin or substrates of organic cation transporters (OCT)1 and OCT2 and multidrug and toxin extrusion protein (MATE)1/2K with fostemsavir coadministration... by Dung Nguyen, Xiusheng Miao, Kunal Taskar, Mindy Magee, Pete Gorycki, Katy Moore, Guoying Tai

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