Search Results - "pharmacokinetics"

In vitro PK/PD modeling of tyrosine kinase inhibitors in non‐small cell lung cancer cell lines by Linda Wanika, Neil D. Evans, Martin Johnson, Helen Tomkinson, Michael J. Chappell

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Scaling Pharmacodynamics from Rats to Humans to Support Erythropoietin and Romiplostim Combination Therapy to Treat Erythropoietin-Resistant Anemia by Xiaoqing Fan, Wojciech Krzyzanski, Dongyang Liu, Raymond S. M. Wong, Xiaoyu Yan

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Midazolam-sirupus, formulation and pharmacodynamic efficacy by K. Goracinova, K. Mladenovska, O. Gelevska, E. Fredro-Kumbaradzi, M. Glavas-Dodov, J. Nanceva

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Exploring molecular docking with E-pharmacophore and QSAR models to predict potent inhibitors of 14-α-demethylase protease from Moringa spp by Damilola Alex Omoboyowa

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Thermosensitive porphyrin-incorporated hydrogel with four-arm PEG-PCL copolymer (II): doxorubicin loaded hydrogel as a dual fluorescent drug delivery system for simultaneous imagin... by Xia Dong, Hongli Chen, Jingwen Qin, Chang Wei, Jie Liang, Tianjun Liu, Deling Kong, Feng Lv

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Evaluation of commonly used cardiovascular drugs in inhibiting vonoprazan metabolism in vitro and in vivo by Yiran Wang, Yiran Wang, Jihua Shi, Dapeng Dai, Jianping Cai, Shuanghu Wang, Yun Hong, Shan Zhou, Fangling Zhao, Fangling Zhao, Quan Zhou, Peiwu Geng, Yunfang Zhou, Xue Xu, Qingfeng Luo

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Structural principles of insulin formulation and analog design: A century of innovation by Mark A. Jarosinski, Balamurugan Dhayalan, Yen-Shan Chen, Deepak Chatterjee, Nicolás Varas, Michael A. Weiss

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Stoichiometry of multi-specific immune checkpoint RNA Abs for T cell activation and tumor inhibition using ultra-stable RNA nanoparticles by Dan Shu, Long Zhang, Xuefeng Bai, Jianhua Yu, Peixuan Guo

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Novel Mechanistic PBPK Model to Predict Renal Clearance in Varying Stages of CKD by Incorporating Tubular Adaptation and Dynamic Passive Reabsorption by Weize Huang, Nina Isoherranen

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Development and characterization of liposomal formulation of bortezomib by Anil K. Deshantri, Josbert M. Metselaar, Stavroula Zagkou, Gert Storm, Sanjay N. Mandhane, Marcel H.A.M. Fens, Raymond M. Schiffelers

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Evolving drug regulatory landscape in China: A clinical pharmacology perspective by Weifeng Tang, Ying Huang, Diansong Zhou, Yao Huang, Yingxue Chen, Song Ren, Yan Li, Shengqian Wu, Xiaoying Zhao, Xuyang Song, Haidong Wang, Yuwen Jin, Hongtao Yu, Li Zhang, Yunfei Li, David Boulton, Kevin Shen

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Impact of SLCO1B1 Genetic Variation on Rosuvastatin Systemic Exposure in Pediatric Hypercholesterolemia by Jonathan B. Wagner, Susan Abdel‐Rahman, Andrea Gaedigk, Roger Gaedigk, Geetha Raghuveer, Vincent S. Staggs, Leon Van Haandel, J. Steven Leeder

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The biased apelin receptor agonist, MM07, reverses Sugen/hypoxia-induced pulmonary arterial hypertension as effectively as the endothelin antagonist macitentan by Thomas L. Williams, Duuamene Nyimanu, Rhoda E. Kuc, Richard Foster, Robert C. Glen, Robert C. Glen, Janet J. Maguire, Anthony P. Davenport

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Building an adaptive dose simulation framework to aid dose and schedule selection by Richard Hooijmaijers, Ridhi Parasrampuria, Eleonora Marostica, Geraldine Ferron‐Brady, Teun M. Post, Sandra A. G. Visser

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Lipid Composition-, Medium pH-, and Drug-Concentration-Dependent Membrane Interactions of Ibuprofen, Diclofenac, and Celecoxib: Hypothetical Association with Their Analgesic and Ga... by Maki Mizogami, Hironori Tsuchiya

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Simultaneous LC-ESI-MS/MS Quantification of Levosimendan and Its Metabolites for Therapeutic Drug Monitoring of Cardiac Surgery Patients by Hannah Kipka, Roland Tomasi, Max Hübner, Uwe Liebchen, Christian Hagl, Klaus T. Wanner, Hanna Mannell, Georg Höfner

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Therapeutic Potential of AntagomiR-23b for Treating Myotonic Dystrophy by Estefanía Cerro-Herreros, Irene González-Martínez, Nerea Moreno-Cervera, Sarah Overby, Manuel Pérez-Alonso, Beatriz Llamusí, Rubén Artero

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Simultaneous Quantification of Seven Antifungal Agents in Human Serum Using Liquid Chromatography-Tandem Mass Spectrometry by Wenjing Li, Yang Li, Junlong Cai, Yue Wang, Yanan Liu, Hankun Hu, Liang Liu

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Synthesis and Characterization of Nano-Sized 4-Aminosalicylic Acid-Sulfamethazine Cocrystals by Ala' Salem, Anna Takácsi-Nagy, Sándor Nagy, Alexandra Hagymási, Fruzsina Gősi, Barbara Vörös-Horváth, Tomislav Balić, Szilárd Pál, Aleksandar Széchenyi

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Clinical decision support for chemotherapy‐induced neutropenia using a hybrid pharmacodynamic/machine learning model by Jasmine H. Hughes, Dominic M. H. Tong, Vanessa Burns, Bobby Daly, Pedram Razavi, Jaap J. Boelens, Srijib Goswami, Ron J. Keizer

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