Search Results - "pharmacokinetics"

Intracellular and Plasma Trough Concentration and Pharmacogenetics of Telaprevir by Jessica Cusato, Sarah Allegra, Amedeo De Nicolò, Lucio Boglione, Giovanna Fatiguso, Adnan Mohamed Abdi, Giuseppe Cariti, Giovanni Di Perri, Antonio D'Avolio

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Incorporation of ion exchange functionalized-montmorillonite into solid lipid nanoparticles with low irritation enhances drug bioavailability for glaucoma treatment by Shuo Liu, Xinyue Han, Hanyu Liu, Yawen Zhao, Huamei Li, Ilva D. Rupenthal, Zhufen Lv, Yanzhong Chen, Fan Yang, Qineng Ping, Yufang Pan, Dongzhi Hou

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Design, synthesis, and biological evaluation of 2,4-dimorpholinopyrimidine-5-carbonitrile derivatives as orally bioavailable PI3K inhibitors by Daowei Huang, Daowei Huang, Daowei Huang, Jixia Yang, Qingwei Zhang, Xiaolei Zhou, Yanbo Wang, Zhenhua Shang, Zhenhua Shang, Zhenhua Shang, Jianqi Li, Baoyin Zhang

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Localization of ^99mTc-GRP Analogs in GRPR-Expressing Tumors: Effects of Peptide Length and Neprilysin Inhibition on Biological Responses by Aikaterini Kaloudi, Emmanouil Lymperis, Panagiotis Kanellopoulos, Beatrice Waser, Marion de Jong, Eric P. Krenning, Jean Claude Reubi, Berthold A. Nock, Theodosia Maina

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Orally delivered rutin in lipid-based nano-formulation exerts strong antithrombotic effects by protein disulfide isomerase inhibition by Dan Chen, Yurong Liu, Peiwen Liu, Yang Zhou, Longguang Jiang, Cai Yuan, Mingdong Huang

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Probing In Silico the Benzimidazole Privileged Scaffold for the Development of Drug-like Anti-RSV Agents by Elena Cichero, Alessio Calautti, Valeria Francesconi, Michele Tonelli, Silvia Schenone, Paola Fossa

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Formulation, characterization, optimization, and in-vivo performance of febuxostat self-nano-emulsifying system loaded sublingual films by Basant A. Habib, Amina S. Abd El-Samiae, Boushra M. El-Houssieny, Randa Tag

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A novel matrix dispersion based on phospholipid complex for improving oral bioavailability of baicalein: preparation, in vitro and in vivo evaluations by Yang Zhou, Wujun Dong, Jun Ye, Huazhen Hao, Junzhuo Zhou, Renyun Wang, Yuling Liu

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Synthesis, 3D-QSAR, and Molecular Modeling Studies of Triazole Bearing Compounds as a Promising Scaffold for Cyclooxygenase-2 Inhibition by Ranza Elrayess, Mohamed Saleh Elgawish, Marwa Elewa, Mohamed S. Nafie, Sameh S. Elhady, Asmaa S. A. Yassen

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Using novobiocin as a specific inhibitor of breast cancer resistant protein to assess the role of transporter in the absorption and disposition of topotecan by Yaming Su, Peidi Hu, Sung-Hack Lee, Patrick J Sinko

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Effects of sedative psychotropic drugs combined with oxycodone on respiratory depression in the rat by Lin Xu, Ashok Krishna, Sharron Stewart, Katherine Shea, Rebecca Racz, James L. Weaver, Donna A. Volpe, Nageswara R. Pilli, Suresh Narayanasamy, Jeffry Florian, Vikram Patel, Murali K. Matta, Marc B. Stone, Hao Zhu, Michael C. Davis, David G. Strauss, Rodney Rouse

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Evaluation of moxifloxacin in canine and non‐human primate telemetry assays: Comparison of QTc interval prolongation by timepoint and concentration‐QTc analysis by Ray W. Chui, Joel Baublits, Fiona A. Chandra, Zack W. Jones, Michael J. Engwall, Hugo M. Vargas

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Biliary excretion and enterohepatic circulation of thienorphine and its glucuronide conjugate in rats by Jingting Deng, Xiaomei Zhuang, Guolin Shen, Hua Li, Zehui Gong

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Modulation of Multispecific Transporters by <i>Uncaria tomentosa</i> Extract and Its Major Phytoconstituents by Nóra Szilvásy, Panna Lajer, Attila Horváth, Katalin Veres, Judit Hohmann, Zsuzsanna Schelz, Renáta Minorics, István Zupkó, Zsuzsanna Gáborik, Emese Kis, Csilla Temesszentandrási-Ambrus

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In vitro mechanistic study on mycophenolate mofetil drug interactions: effect of prednisone, cyclosporine, and others by Junjun Mao, Feifei Yu, Weiwei Qin, Guixian She, Yi Rong, Zhuohan Hu, Mingkang Zhong

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Implementation of a reference-scaled average bioequivalence approach for highly variable generic drug products of agomelatine in Chinese subjects by Fang Tang, Rui Zhou, Zeneng Cheng, Guoping Yang, Aiqiao Chen, Zhi Liu, Hongyi Tan, Shuang Yang, Sanwang Li, Lingli Mu, Peng Yu

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Effeciveness of Citalopram, Alprazolam and Clomipramine in Amelioration of Negative Sympotoms in Schizphrenia by Saeed Shoja'-Shafti

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Modelling intramuscular drug fate in vitro with tissue-relevant biomimetic hydrogels by Adam McCartan, Julia Mackay, David Curran, Randall J Mrsny

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Radiopharmaceutical Formulation and Preclinical Testing of ⁶⁸Ga-Labeled DOTA-MGS5 for the Regulatory Approval of a First Exploratory Clinical Trial by Anton A. Hörmann, Maximilian Klingler, Christine Rangger, Christian Mair, Clemens Decristoforo, Christian Uprimny, Irene J. Virgolini, Elisabeth von Guggenberg

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First‐in‐human study with SAR445088: A novel selective classical complement pathway inhibitor by Timothy Chow, Pirouz Shamszad, Christopher Vinnard, Esther Yoon, Julia Belinski, Irene Karpenko, Laurent Perrin, Kristen Auwarter, Michael Storek, Howard Surks, Nancy Wong, Yehuda Z. Cohen

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