Search Results - "pharmacokinetics"

Pharmacodynamic Evaluation and PK/PD-Based Dose Prediction of Tulathromycin: A Potential New Indication for Streptococcus suis Infection by Yu-Feng Zhou, Yu-Feng Zhou, Hui-Min Peng, Hui-Min Peng, Ming-Xiao Bu, Ming-Xiao Bu, Ya-Hong Liu, Ya-Hong Liu, Jian Sun, Jian Sun, Xiao-Ping Liao, Xiao-Ping Liao

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Relative bioavailability of diazoxide, manufactured at two different international locations, in healthy participants under fasting conditions: an open-label, two-stage, adaptive,... by Martin Otto Behm, Jialin Xu, Deborah Panebianco, Paul Fackler

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Lipid-based nanosystem of edaravone: development, optimization, characterization and in vitro/in vivo evaluation by Ankit Parikh, Krishna Kathawala, Chun Chuan Tan, Sanjay Garg, Xin-Fu Zhou

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Preparing and assessing the physiochemical properties of curcumin niosomes and evaluating their cytotoxicity in 3T3 and MCF-7 cell lines by Narges Ashraf Ganjooei, Mandana Ohadi, Seyyed Mohammad Amin Mostafavi, Behzad Behnam, Abbas Pardakhty

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Self-emulsifying micelles as a drug nanocarrier system for itraconazole oral bioavailability enhancement; in vitro and in vivo assessment by Nayyer Islam, Naveed Ullah Khan, Anam Razzaq, Zaheer Ullah Khan, Farid Menaa, Mohammad Y. Alfaifi, Serag Eldin I. Elbehairi, Haroon Iqbal, Jiang Ni

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Orally administered intelligent self-ablating nanoparticles: a new approach to improve drug cellular uptake and intestinal absorption by Yanzi Liang, Ruihuan Ding, Huihui Wang, Lanze Liu, Jibiao He, Yuping Tao, Zhenyu Zhao, Jie Zhang, Aiping Wang, Kaoxiang Sun, Youxin Li, Yanan Shi

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Killing a fly with a sledgehammer: Atezolizumab exposure in real‐world lung cancer patients by Sophie Marolleau, Alice Mogenet, Clara Boeri, Mourad Hamimed, Joseph Ciccolini, Laurent Greillier

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Use of In Vitro Dynamic Colon Model (DCM) to Inform a Physiologically Based Biopharmaceutic Model (PBBM) to Predict the In Vivo Performance of a Modified-Release Formulation of The... by Konstantinos Stamatopoulos, Connor O'Farrell, Mark J. H. Simmons, Hannah K. Batchelor, Nena Mistry

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Studies Regarding Antimicrobial Properties of Some Microbial Polyketides Derived from <i>Monascus</i> Strains by Daniela Albisoru, Nicoleta Radu, Lucia Camelia Pirvu, Amalia Stefaniu, Narcisa Băbeanu, Rusandica Stoica, Dragos Paul Mihai

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Lack of Evidence for Involvement of P-Glycoprotein in Brain Uptake of the Centrally Acting Analgesic, Tramadol in the Rat by Behjat Sheikholeslami, Mehrdad Hamidi, Hoda Lavasani, Mohammad Sharifzadeh, Mohammadreza Rouini

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Design and Evaluation of S-Protected Thiolated-Based Itopride Hydrochloride Polymeric Nanocrystals for Functional Dyspepsia: QbD-Driven Optimization, In Situ, In Vitro, and In Vivo... by Moutaz Y. Badr, Pratap Basim, Khaled M. Hosny, Waleed Y. Rizg, N. Raghavendra Naveen, Mallesh Kurakula, Fayez Alsulaimani, Awaji Y. Safhi, Fahad Y. Sabei, Mohammed Alissa, Abdulmohsin J. Alamoudi

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Antiproliferative Copper(II) Complexes Bearing Mixed Chelating Ligands: Structural Characterization, ROS Scavenging, In Silico Studies, and Anti-Melanoma Activity by Rodica Olar, Catalin Maxim, Mihaela Badea, Mihaela Bacalum, Mina Raileanu, Speranta Avram, Nataša Čelan Korošin, Teodora Burlanescu, Arpad Mihai Rostas

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Identification of ferroptosis as a novel mechanism for antitumor activity of natural product derivative a2 in gastric cancer by Ying Liu, Zan Song, Yajie Liu, Xubin Ma, Wang Wang, Yu Ke, Yichao Xu, Dequan Yu, Hongmin Liu

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Green rush and red warnings: Retrospective chart review of adverse events of interactions between cannabinoids and psychotropic drugs by Adrian Andrzej Chrobak, Jarosław Woroń, Jarosław Woroń, Jarosław Woroń, Marcin Siwek

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Local application of engineered insulin-like growth factor I mRNA demonstrates regenerative therapeutic potential in vivo by Justin S. Antony, Pascale Birrer, Claudia Bohnert, Sina Zimmerli, Petra Hillmann, Hervé Schaffhauser, Christine Hoeflich, Andreas Hoeflich, Ramzi Khairallah, Andreas T. Satoh, Isabelle Kappeler, Isabel Ferreira, Klaas P. Zuideveld, Friedrich Metzger

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The current place of direct oral anticoagulants in the prevention/treatment of venous thromboembolism by Tomić Maja

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A mechanistic PK/PD model to enable dose selection of the potent anti‐tryptase antibody (MTPS9579A) in patients with moderate‐to‐severe asthma by Sharon M. Rymut, Lindsay M. Henderson, Victor Poon, Tracy L. Staton, Fang Cai, Siddharth Sukumaran, Horace Rhee, Ryan Owen, Saroja Ramanujan, Kenta Yoshida

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Matrix Assisted Cocrystallization as an example of continuous and scalable method of obtaining pharmaceutical cocrystals on an industrial scale by Anna Magdalena Gołkowska, Aleksandra Jowita Dyba, Marta Maria Kozakiewicz, Karol Przemysław Nartowski

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PK/PD modeling of FXI antisense oligonucleotides to bridge the dose‐FXI activity relation from healthy volunteers to end‐stage renal disease patients by Stefan Willmann, Eleonora Marostica, Nelleke Snelder, Alexander Solms, Markus Jensen, Maximilian Lobmeyer, Anthonie W. A. Lensing, Claudette Bethune, Erin Morgan, Rosie Z. Yu, Yanfeng Wang, Shiangtung W. Jung, Richard Geary, Sanjay Bhanot

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Vancomycin Serum Concentration after 48 h of Administration: A 3-Years Survey in an Intensive Care Unit by Nicolas Perin, Claire Roger, Grégory Marin, Nicolas Molinari, Alexandre Evrard, Jean-Philippe Lavigne, Saber Barbar, Pierre Géraud Claret, Caroline Boutin, Laurent Muller, Jeffrey Lipman, Jean-Yves Lefrant, Samir Jaber, Jason A. Roberts

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