Zoekresultaten - "pharmacometrics"

Application of multistate modeling to clinical data analysis door Joachim Grevel, Joshua Veasy, Blesson Chacko

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A quantitative approach to the choice of number of samples for percentile estimation in bootstrap and visual predictive check analyses door E. Niclas Jonsson, Joakim Nyberg

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Understanding effect site pharmacology of uprifosbuvir, a hepatitis C virus nucleoside inhibitor: Case study of a multidisciplinary modeling approach in drug development door Paul van den Berg, Wei Gao, Maurice J. Ahsman, Leticia Arrington, Filippos Kesisoglou, Randy Miller, Teun M. Post, Matthew L. Rizk

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A novel Bayesian generative approach for estimating tumor dynamics from published studies door Arya Pourzanjani, Saurabh Modi, Jamie Connarn, Xinwen Zhang, Vijay Upreti, Chih‐Wei Lin, Khamir Mehta

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Deep Learning Methods Applied to Drug Concentration Prediction of Olanzapine door Richard Khusial, Robert R. Bies, Ayman Akil

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A Mechanistic Systems Pharmacology Model for Prediction of LDL Cholesterol Lowering by PCSK9 Antagonism in Human Dyslipidemic Populations door K Gadkar, N Budha, A Baruch, J D Davis, P Fielder, S Ramanujan

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Quantitative Systems Pharmacology and Empirical Models: Friends or Foes? door Neil Benson

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How Do We "Validate" a QSP Model? door Daniel C. Kirouac

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The Risk of Treating Populations Instead of Patients door Amelia N. Deitchman

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Quantitative systems pharmacology in the age of artificial intelligence door Benjamin Ribba

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Response to "mixed‐effects models and the drug titration paradox" door Niels Rode Kristensen, Henrik Agersø

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Quantitative Systems Pharmacology: A Regulatory Perspective on Translation door Issam Zineh

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Industrialization of Quantitative Systems Pharmacology door Brian Topp, Maria E. Trujillo, Vikram Sinha

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The Use of Translational Modelling and Simulation to Develop Immunomodulatory Therapy as an Adjunct to Antibiotic Treatment in the Context of Pneumonia door Robin Michelet, Moreno Ursino, Sandrine Boulet, Sebastian Franck, Fiordiligie Casilag, Mara Baldry, Jens Rolff, Madelé van Dyk, Sebastian G. Wicha, Jean-Claude Sirard, Emmanuelle Comets, Sarah Zohar, Charlotte Kloft

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Population Pharmacokinetics of Intravenous Artesunate: A Pooled Analysis of Individual Data From Patients With Severe Malaria door S G Zaloumis, J Tarning, S Krishna, R N Price, N J White, T M E Davis, J M McCaw, P Olliaro, R J Maude, P Kremsner, A Dondorp, M Gomes, K Barnes, J A Simpson

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Navigating the landscape of parameter identifiability methods: A workflow recommendation for model development door Martijn vanNoort, Martijn Ruppert, Joost DeJongh, Eleonora Marostica, Rolien Bosch, Emir Mešić, Nelleke Snelder

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Introduction of an artificial neural network-based method for concentration‐time predictions door Dominic Stefan Bräm, Neil Parrott, Lucy Hutchinson, Bernhard Steiert

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Modulation of Cell State to Improve Drug Therapy door James M. Gallo

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CYTOCON DB: A versatile database of human cell and molecule concentrations for accelerating model development door Rajat Desikan, Priya Jayachandran

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Time‐varying covariates, overadjustment bias and mediation in pharmacokinetic/pharmacodynamic modeling door Sebastiaan Camiel Goulooze, Nelleke Snelder

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