Zoekresultaten - "pharmacometrics"

The potential and pitfalls of artificial intelligence in clinical pharmacology door Martin Johnson, Mishal Patel, Alex Phipps, Mihaela van derSchaar, Dave Boulton, Megan Gibbs

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US Food and Drug Administration embraces using innovation to identify optimized dosages for patients with cancer door Stacy S. Shord, Hao Zhu, Jiang Liu, Atiqur Rahman, Brian Booth, Issam Zineh

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Physiologically‐based pharmacokinetic modeling for primary metabolites of CYP3A and P‐glycoprotein inhibitors in drug-drug interactions: Should we assume the free drug hypothesis?... door Shinji Yamazaki, Raymond Evers, Loeckie De Zwart

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American Society for Clinical Pharmacology and Therapeutics 2019 Annual Meeting Pre‐Conferences door Jane P.F. Bai, Cynthia J. Musante, Suzana Petanceska, Lei Zhang, Liang Zhao, Ping Zhao

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Response Letter to the Editor: "Assumption Checking Before Application of the Prespecified QT Linear Mixed Effect Model is Essential" door Yeamin Huh, Steve Riley, Timothy Nicholas

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Individualized Absorption Models in Population Pharmacokinetic Analyses door Mutaz M. Jaber, Mahmoud Al‐Kofahi, Kyriakie Sarafoglou, Richard C. Brundage

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Assumption Checking Before Application of the Prespecified QT Linear Mixed Effect Model is Essential door Dinko Rekić, Joanna Parkinson, Holly Kimko

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Development of a cystic fibrosis population model for physiologically based pharmacokinetic models: Is it worth it? door Eunjin Hong, Paul M. Beringer

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Moving the needle for oncology dose optimization: A call for action door Karthik Venkatakrishnan, Priya Jayachandran, Shirley K. Seo, Piet H. van derGraaf, John A. Wagner, Neeraj Gupta

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Quantitative Prediction of Drug-Drug Interactions Involving Inhibitory Metabolites by Physiologically Based Pharmacokinetic Models: Is it Worth It? door M Tod, S Goutelle, L Bourguignon, N Bleyzac

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Editorial: Emerging talents in Frontiers in Pharmacology: Drug metabolism and transport 2022 door Terry D. Hinds, Massimo Valoti, Yurong Lai, Thomas P. C. Dorlo, Yan Li

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Estimands-What they are and why they are important for pharmacometricians door Mouna Akacha, Christian Bartels, Björn Bornkamp, Frank Bretz, Neva Coello, Thomas Dumortier, Michael Looby, Oliver Sander, Heinz Schmidli, Jean‐Louis Steimer, Camille Vong

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Antibodies to Modulate Surface Receptor Systems Are Often Bivalent and Must Compete in a Two‐Dimensional Cell Contact Region door Brian J. Schmidt, Christine Bee, Minhua Han, Yawu Jing, Yougan Cheng, Daniel J. Tenney, Tarek A. Leil

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Methods for Predicting Diabetes Phase III Efficacy Outcome From Early Data: Superior Performance Obtained Using Longitudinal Approaches door JB Møller, NR Kristensen, S Klim, MO Karlsson, SH Ingwersen, MC Kjellsson

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Increasing impact of quantitative methods and modeling in establishment of bioequivalence and characterization of drug delivery door Miyoung Yoon, Andrew Babiskin, Meng Hu, Fang Wu, Sam G. Raney, Lanyan Fang, Liang Zhao

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EMA perspective on the value of model‐informed drug development for labeling recommendations regarding medicine use during pregnancy and breastfeeding door Efthymios Manolis, Flora Tshinanu Musuamba, Corinne S. deVries, Pieter J. Colin, Martin B. Oleksiewicz

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Pharmacokinetic Characterization to Enable Medicine Use in Pregnancy, the Potential Role of Physiologically‐Based Pharmacokinetic Modeling: A Regulatory Perspective door Susan Cole, Paola Coppola, Essam Kerwash, Janet Nooney, Siu Ping Lam

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Considerations for Adapting Pre-existing Mechanistic Quantitative Systems Pharmacology Models for New Research Contexts door Michael Weis, Rebecca Baillie, Christina Friedrich

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Enhancing inclusivity in clinical trials: Model‐informed drug development for pregnant individuals in the era of personalized medicine door André Dallmann, Peter L. Bonate, Janelle Burnham, Blessy George, Lynne Yao, Jane Knöchel

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Population Pharmacokinetics of CC-122 door Cheng Y, Chen J, Pourdehnad M, Zhou S, Li Y

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