Search Results - "phosphorylation"

Safety, pharmacokinetics and target engagement of novel RIPK1 inhibitor SAR443060 (DNL747) for neurodegenerative disorders: Randomized, placebo‐controlled, double‐blind phase I/Ib... by Maurits F. J. M. Vissers, Jules A. A. C. Heuberger, Geert Jan Groeneveld, Jerome Oude Nijhuis, Peter Paul De Deyn, Salah Hadi, Jeffrey Harris, Richard M. Tsai, Andres Cruz‐Herranz, Fen Huang, Vincent Tong, Rebecca Erickson, Yuda Zhu, Kimberly Scearce‐Levie, Jennifer Hsiao‐Nakamoto, Xinyan Tang, Megan Chang, Brian M. Fox, Anthony A. Estrada, Robert J. Pomponio, Miguel Alonso‐Alonso, Moshe Zilberstein, Nazem Atassi, Matthew D. Troyer, Carole Ho

Connect to this object online.

Isolation and anti-neuroinflammation activity of sesquiterpenoids from Artemisia argyi: computational simulation and experimental verification by Caiwenjie La, Menghe Li, Zexu Wang, Tao Liu, Qiongzhen Zeng, Pinghua Sun, Zhe Ren, Cuifang Ye, Qiuying Liu, Yifei Wang

Connect to this object online.

Morinda officinalis iridoid glycosides, as an inhibitor of GSK-3β, alleviates rheumatoid arthritis through inhibition of NF-κB and JAK2/STAT3 pathway by Yi Shen, Ronghua Bao, Xinyuan Ye, Heming Li, Yiqi Sun, Qiuru Ren, Jinman Du, Tianwen Ye, Quanlong Zhang, Qiming Zhao, Ting Han, Luping Qin, Qiaoyan Zhang

Connect to this object online.

Suan-Zao-Ren Decoction ameliorates synaptic plasticity through inhibition of the Aβ deposition and JAK2/STAT3 signaling pathway in AD model of APP/PS1 transgenic mice by Qing-Hua Long, Yong-Gui Wu, Li-Ling He, Li Ding, Ai-Hua Tan, He-Yuan Shi, Ping Wang

Connect to this object online.

Limited impact on glucose homeostasis of leptin receptor deletion from insulin- or proglucagon-expressing cells by Helen Soedling, David J. Hodson, Alice E. Adrianssens, Fiona M. Gribble, Frank Reimann, Stefan Trapp, Guy A. Rutter

Connect to this object online.

Efficacy of probiotic Streptococcus thermophilus in counteracting TGF-β1-induced fibrotic response in normal human dermal fibroblasts by Francesca Lombardi, Francesca Rosaria Augello, Serena Artone, Blerina Bahiti, Jenna Marie Sheldon, Maurizio Giuliani, Maria Grazia Cifone, Paola Palumbo, Benedetta Cinque

Connect to this object online.

Sodium butyrate alleviates R97-116 peptide-induced myasthenia gravis in mice by improving the gut microbiota and modulating immune response by Jing Sun, Juanjuan Chen, Qinfang Xie, Mengjiao Sun, Wenjing Zhang, Hongxia Wang, Ning Liu, Qi Wang, Manxia Wang

Connect to this object online.

Enhanced Activation of mTOR Signaling Pathway Was Found in the Hypertrophic and Nodular Lesions of Port Wine Stains by Xu MN, Wang Q, Wang M, Xu Y, Yuan SM

Connect to this object online.

β-aminoisobutyrics acid, a metabolite of BCAA, activates the AMPK/Nrf-2 pathway to prevent ferroptosis and ameliorates lung ischemia-reperfusion injury by Ziyue Zhang, Xingbing Li, Jingwen Guo, Bo He, Lianpan Wu, Rongpei Yang, Xingyue Li, Dandong Fang, XiaoLi Yang, Donghai Yang, Fengxian Wang, Ming Tang, Yu Han, Pedro A. Jose, Hongyong Wang, Chunyu Zeng

Connect to this object online.

Traditional Chinese Medicine, Qingfei Paidu Decoction and Xuanfei Baidu Decoction, Inhibited Cytokine Production via NF-κB Signaling Pathway in Macrophages: Implications for Corona... by Yujia Li, Yujia Li, Bin Li, Pan Wang, Qinghua Wang

Connect to this object online.

The small molecule SERCA activator CDN1163 increases energy metabolism in human skeletal muscle cells by Abel M. Mengeste, Jenny Lund, Parmeshwar Katare, Roya Ghobadi, Hege G. Bakke, Per Kristian Lunde, Lars Eide, Gavin O' Mahony, Sven Göpel, Xiao-Rong Peng, Eili Tranheim Kase, G. Hege Thoresen, Arild C. Rustan

Connect to this object online.

Sugiol Masters Apoptotic Precision to Halt Gastric Cancer Cell Proliferation by Tahani Bakhsh, Samah Sulaiman Abuzahrah, Safa H. Qahl, Mohamed A. Akela, Irfan A. Rather

Connect to this object online.

Vagal afferent fibers contribute to the anti-inflammatory reactions by vagus nerve stimulation in concanavalin A model of hepatitis in rats by Byung Gon Jo, Seung-Hyung Kim, Uk Namgung

Connect to this object online.

Aldosterone Jeopardizes Myocardial Insulin and β-Adrenergic Receptor Signaling via G Protein-Coupled Receptor Kinase 2 by Alessandro Cannavo, Alessandro Cannavo, Federica Marzano, Andrea Elia, Daniela Liccardo, Leonardo Bencivenga, Giuseppina Gambino, Claudia Perna, Antonio Rapacciuolo, Antonio Cittadini, Nicola Ferrara, Nicola Ferrara, Nazareno Paolocci, Nazareno Paolocci, Walter J. Koch, Giuseppe Rengo, Giuseppe Rengo

Connect to this object online.

High Mobility Group Box1 Inhibitor Glycyrrhizic Acid Attenuates Kidney Injury in Streptozotocin-Induced Diabetic Rats by Hong Zhang, Ru Zhang, Juan Chen, Min Shi, Wei Li, Xiangcheng Zhang

Connect to this object online.

Bcl-2-like protein-10 increases aggressive features of melanoma cells by Donatella Del Bufalo, Marta Di Martile, Elisabetta Valentini, Isabella Manni, Ilenia Masi, Antonella D'Amore, Antonio Filippini, Carmine Nicoletti, Marco Zaccarini, Carlo Cota, Maria Victoria Castro, María Josefina Quezada, Laura Rosanò, Pablo Lopez-Bergami, Simona D'Aguanno

Connect to this object online.

Estrogen receptor-α in female skeletal muscle is not required for regulation of muscle insulin sensitivity and mitochondrial regulation by Melissa R. Iñigo, Adam J. Amorese, Michael D. Tarpey, Nicholas P. Balestrieri, Keith G. Jones, Daniel J. Patteson, Kathryn C. Jackson, Maria.J. Torres, Chien-Te Lin, Cody D. Smith, Timothy D. Heden, Shawna L. McMillin, Luke A. Weyrauch, Erin C. Stanley, Cameron A. Schmidt, Brita B. Kilburg-Basnyat, Sky W. Reece, Christine E. Psaltis, Leslie A. Leinwand, Katsu Funai, Joseph M. McClung, Kymberly M. Gowdy, Carol A. Witczak, Dawn A. Lowe, P. Darrell Neufer, Espen E. Spangenburg

Connect to this object online.

Deferoxamine Treatment Effectively Prevents Periodontitis Progression by Reducing Inflammation and Osteoclastogenesis in Experimental Periodontitis Rats by Zhu Y, Qiao S, Pang Y, Wang H, Zhou Y

Connect to this object online.

Urolithin A attenuates osteoclast differentiation and compensates for ovariectomy-induced bone loss in mice by inhibiting PI3K/AKT/mTOR signaling pathway by Wenyun Zhou, Weijun Zhou, Zibin Zhou, Yonghao Bi, Zhigao Zhou, Shaozhe Chen, Zihong Lin, Jiajie Ye, Gang Xie, Wenjie Liu, Dantao Xie, Zhen Lian, Ruiwu Zheng, Xianghua Hu, Xinjia Wang, Guixin Yuan, Guanfeng Yao

Connect to this object online.

Tumour‐induced alterations in single‐nucleus transcriptome of atrophying muscles indicate enhanced protein degradation and reduced oxidative metabolism by Samet Agca, Aylin Domaniku‐Waraich, Sevval Nur Bilgic, Melis Sucuoglu, Meric Dag, Sukru Anil Dogan, Serkan Kir

Connect to this object online.