Search Results - "polypeptide"

PACAP38 synergizes with irradiation to suppress the proliferation of multiple cancer cells via regulating SOX6/Wnt/β-catenin signaling by Ran Wu, Ran Wu, Chun-Xiang Cao, Chun-Xiang Cao, Chun-Xiang Cao, Lu Cao, Lu Cao, Jun Su, Ke-Man Liao, Ke-Man Liao, Huan Li, Huan Li, Qian Zhu, Qian Zhu, Shu-Yan Li, Shu-Yan Li, Min Li, Min Li, Jia-Yi Chen, Jia-Yi Chen

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The Active Glucuronide Metabolite of the Brain Protectant IMM-H004 with Poor Blood-Brain Barrier Permeability Demonstrates a High Partition in the Rat Brain via Multiple Mechanisms by Jianwei Jiang, Lijun Luo, Ziqian Zhang, Xiao Liu, Naihong Chen, Yan Li, Li Sheng

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A long‐acting GDF15 analog causes robust, sustained weight loss and reduction of food intake in an obese nonhuman primate model by Songmao Zheng, David Polidori, Yuanping Wang, Brian Geist, Xiefan Lin‐Schmidt, Jennifer L. Furman, Serena Nelson, Andrea R. Nawrocki, Simon A. Hinke

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Clinical assessment of momelotinib drug-drug interactions via CYP3A metabolism and transporters by Yu Liu Ho, Pete Gorycki, Geraldine Ferron‐Brady, Paul Martin, Georgios Vlasakakis

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Regulatory guidelines do not accurately predict tolvaptan and metabolite interactions at BCRP, OATP1B1, and OAT3 transporters by Susan E. Shoaf, Patricia Bricmont, Jennifer Repella Gordon

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Biological Distribution after Oral Administration of Radioiodine-Labeled Acetaminophen to Estimate Gastrointestinal Absorption Function via OATPs, OATs, and/or MRPs by Kakeru Sato, Asuka Mizutani, Yuka Muranaka, Jianwei Yao, Masato Kobayashi, Kana Yamazaki, Ryuichi Nishii, Kodai Nishi, Takeo Nakanishi, Ikumi Tamai, Keiichi Kawai

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Serum sirtuin-1 a potential marker in the diagnosis of rheumatoid arthritis by Liming Tan, Tanglin Ouyang, Xu Li, Yinyi Chen, Shipeng Ke, Jiayuan Chen, Ye Liu, Fajun Zeng, Yingxing Chen, Jing Long, Qingyue Deng, Xiaoyan Hu

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Treatment with metformin and a dipeptidyl peptidase-4 inhibitor elevates apelin levels in patients with type 2 diabetes mellitus by Fan YJ, Zhang Y, Li XS, Zheng H, Song YP, Zhang N, Shen CF, Fan XF, Ren FD, Shen JY, Ren GG, Yang JL

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The utility of endogenous glycochenodeoxycholate-3-sulfate and 4β-hydroxycholesterol to evaluate the hepatic disposition of atorvastatin in rats by Yanrong Ma, Mingyan Xin, Yuanjie Wen, Huan Wang, Guoqiang Zhang, Jianye Dai, Xin-An Wu

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Elabela Attenuates the TGF-β1-Induced Epithelial-Mesenchymal Transition of Peritoneal Mesothelial Cells in Patients Receiving Peritoneal Dialysis by Shunyun Xie, Feng Xu, Yue Lu, Yixian Zhang, Xinyang Li, Mengyuan Yu, Wenpeng Cui

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INITIATING PATIENTS ON GLP-1/COMBINED GLP-1 AND GIP AGONISTS: A QUALITY IMPROVEMENT PROJECT by Shreya Srivastava, MD, MPH

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Investigation of pharmacokinetic drug interaction between clesacostat and DGAT2 inhibitor ervogastat in healthy adult participants by Aarti Sawant‐Basak, Arthur J. Bergman, Jessica Mancuso, Sakambari Tripathy, James R. Gosset, Laure Mendes da Costa, William P. Esler, Roberto A. Calle

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An open-label, controlled trial of the clinical effects of Laennec® in patients with nonalcoholic steatohepatitis or cirrhosis by M. Imawari, M. Nagase, I. Yu. Torshin, O. A. Gromova

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Will Tirzepatide become a game-changer in the pharmacological treatment of obesity? - literature review by Aleksandra Doryń, Kinga Woźniak, Magdalena Jung, Maximilian Jung, Patryk Hedesz, Klaudia Warzycka, Monika Gardian-Baj, Alicja Szczerbiak, Wiktoria Ulicka, Katarzyna Kuśmierczyk, Karolina Maliszewska

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Melatonin Modulates the Antioxidant Defenses and the Expression of Proinflammatory Mediators in Pancreatic Stellate Cells Subjected to Hypoxia by Matias Estaras, Manuel R. Gonzalez-Portillo, Remigio Martinez, Alfredo Garcia, Mario Estevez, Miguel Fernandez-Bermejo, Jose M. Mateos, Daniel Vara, Gerardo Blanco-Fernández, Diego Lopez-Guerra, Vicente Roncero, Gines M. Salido, Antonio Gonzalez

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PBPK modeling to predict drug‐drug interactions of ivosidenib as a perpetrator in cancer patients and qualification of the Simcyp platform for CYP3A4 induction by Jayaprakasam Bolleddula, Alice Ke, Hua Yang, Chandra Prakash

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Molecular Expression and Characterization of Erythroid-Specific 5-Aminolevulinate Synthase Gain-of-Function Mutations Causing X-Linked Protoporphyria by David F. Bishop, Vassili Tchaikovskii, Irina Nazarenko, Robert J. Desnick

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An INSULIN and IAPP dual reporter enables tracking of functional maturation of stem cell-derived insulin producing cells by Carmen L. Bayly, Xiao-Qing Dai, Cuilan Nian, Paul C. Orban, C. Bruce Verchere, Patrick E. MacDonald, Francis C. Lynn

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Structure and Dynamics of a Site-Specific Labeled Fc Fragment with Altered Effector Functions by D. Travis Gallagher, Chris McCullough, Robert G. Brinson, Joomi Ahn, John P. Marino, Nazzareno Dimasi

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Xiaozhang Tie Improves Intestinal Motility in Rats With Cirrhotic Ascites by Regulating the Stem Cell Factor/c-kit Pathway in Interstitial Cells of Cajal by Qiang Zhao, Feng Xing, Yanyan Tao, Hongliang Liu, Kai Huang, Yuan Peng, Nianping Feng, Chenghai Liu, Chenghai Liu, Chenghai Liu, Chenghai Liu

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