Search Results - "protein engineering"

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  1. 61
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    Design and characteristics of cytotoxic fibroblast growth factor 1 conjugate for fibroblast growth factor receptor-targeted cancer therapy by Szlachcic A, Zakrzewska M, Lobocki M, Jakimowicz P, Otlewski J

    Published 2016
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  2. 62
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    Dimeric Lectin Chimeras as Novel Candidates for Gb3-Mediated Transcytotic Drug Delivery through Cellular Barriers by Maokai Xu, Maria Antonova, Pavel Salavei, Katharina Illek, Ana Valeria Meléndez, Ramin Omidvar, Roland Thuenauer, Olga Makshakova, Winfried Römer

    Published 2023
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  3. 63
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    A bioengineered anti‐VEGF protein with high affinity and high concentration for intravitreal treatment of wet age‐related macular degeneration by Chengnan Huang, Yuelin Wang, Jinliang Huang, Huiqin Liu, Zhidong Chen, Yang Jiang, Youxin Chen, Feng Qian

    Published 2024
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  4. 64
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    Journey of TRAIL from bench to bedside and its potential role in immuno-oncology by George E. Naoum, Donald J. Buchsbaum, Fady Tawadros, Ammad Farooqi, Waleed O. Arafat

    Published 2017
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  5. 65
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    Structural principles of insulin formulation and analog design: A century of innovation by Mark A. Jarosinski, Balamurugan Dhayalan, Yen-Shan Chen, Deepak Chatterjee, Nicolás Varas, Michael A. Weiss

    Published 2021
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  6. 66
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    Improving the pharmacokinetics, biodistribution and plasma stability of monobodies by Adrian Valentin Dinh-Fricke, Oliver Hantschel

    Published 2024
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  7. 67
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    AlbuCORE: an albumin-based molecular scaffold for multivalent biologics design by Mario Sanches, Igor D'Angelo, Maria Jaramillo, Jason Baardsnes, John Zwaagstra, Joe Schrag, Ian Schoenhofen, Mauro Acchione, Sam Lawn, Grant Wickman, Nina Weisser, David K. Y. Poon, Gordon Ng, Surjit Dixit

    Published 2020
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  8. 68
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    Engineering hydrophobicity and manufacturability for optimized biparatopic antibody-drug conjugates targeting c-MET by Andreas Evers, Simon Krah, Deniz Demir, Ramona Gaa, Desislava Elter, Christian Schroeter, Stefan Zielonka, Nicolas Rasche, Julia Dotterweich, Christine Knuehl, Achim Doerner

    Published 2024
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  9. 69
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    Engineering miniature CRISPR-Cas Un1Cas12f1 for efficient base editing by Yueer Hu, Linxiao Han, Qiqin Mo, Zengming Du, Wei Jiang, Xia Wu, Jing Zheng, Xiao Xiao, Yadong Sun, Hanhui Ma

    Published 2024
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  10. 70
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    Repurposing the McoTI-II Rigid Molecular Scaffold in to Inhibitor of 'Papain Superfamily' Cysteine Proteases by Manasi Mishra, Vigyasa Singh, Meenakshi B. Tellis, Rakesh S. Joshi, Shailja Singh

    Published 2020
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  11. 71
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    Rationally designed Campylobacter jejuni Cas9 enables efficient gene activation and base editing by Yuxi Chen, Rui Kang, Yuanling Jiang, Qi Zheng, Yue Yang, Jiaqi Liu, Guanglan Wu, Weijun Zhao, Zhan Li, Chengxiang Peng, Pengfei Zhang, Fei Peng, Qianyi Liu, Sihui Hu, Xiao Luo, Guifang Wu, Kaixin Cui, Junjiu Huang, Yongming Wang, Zhou Songyang, Puping Liang

    Published 2024
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  12. 72
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    Gene Silencing Mediated by siRNA-binding Fusion Proteins Is Attenuated by Double-stranded RNA-binding Domain Structure by James C Geoghegan, Brian L Gilmore, Beverly L Davidson

    Published 2012
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  13. 73
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    Glycan Profile Analysis of Engineered Trastuzumab with Rationally Added Glycosylation Sequons Presents Significantly Increased Glycan Complexity by Esteban Cruz, Vicki Sifniotis, Zeynep Sumer-Bayraktar, Mouhamad Reslan, Lorna Wilkinson-White, Stuart Cordwell, Veysel Kayser

    Published 2021
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  14. 74
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    Genome scale analysis of pathogenic variants targetable for single base editing by Alexander V. Lavrov, Georgi G. Varenikov, Mikhail Yu Skoblov

    Published 2020
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  15. 75
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    Development of a high yielding expression platform for the introduction of non-natural amino acids in protein sequences by Gargi Roy, Jason Reier, Andrew Garcia, Tom Martin, Megan Rice, Jihong Wang, Meagan Prophet, Ronald Christie, William Dall'Acqua, Sanjeev Ahuja, Michael A Bowen, Marcello Marelli

    Published 2020
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  16. 76
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    A novel conditional active biologic anti-EpCAM x anti-CD3 bispecific antibody with synergistic tumor selectivity for cancer immunotherapy by Gerhard Frey, Ana Paula G. Cugnetti, Haizhen Liu, Charles Xing, Christina Wheeler, Hwai Wen Chang, William J. Boyle, Jay M. Short

    Published 2024
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  17. 77
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    Engineering an anti-CD52 antibody for enhanced deamidation stability by Huawei Qiu, Ronnie Wei, Julie Jaworski, Ekaterina Boudanova, Heather Hughes, Scott VanPatten, Anders Lund, Jaime Day, Yanfeng Zhou, Tracey McSherry, Clark Q. Pan, Rebecca Sendak

    Published 2019
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  18. 78
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    Predicting Antibody Developability Profiles Through Early Stage Discovery Screening by Marc Bailly, Carl Mieczkowski, Veronica Juan, Essam Metwally, Daniela Tomazela, Jeanne Baker, Makiko Uchida, Ester Kofman, Fahimeh Raoufi, Soha Motlagh, Yao Yu, Jihea Park, Smita Raghava, John Welsh, Michael Rauscher, Gopalan Raghunathan, Mark Hsieh, Yi-Ling Chen, Hang Thu Nguyen, Nhung Nguyen, Dan Cipriano, Laurence Fayadat-Dilman

    Published 2020
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  19. 79
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    Simultaneous Control of <i>Staphylococcus aureus</i> and <i>Bacillus cereus</i> Using a Hybrid Endolysin LysB4EAD-LysSA11 by Bokyung Son, Minsuk Kong, Yoyeon Cha, Jaewoo Bai, Sangryeol Ryu

    Published 2020
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  20. 80
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    Recombinant Proteins for Assembling as Nano- and Micro-Scale Materials for Drug Delivery: A Host Comparative Overview by José Luis Corchero, Marianna T. P. Favaro, Merce Márquez-Martínez, Jara Lascorz, Carlos Martínez-Torró, Julieta M. Sánchez, Hèctor López-Laguna, Luís Carlos de Souza Ferreira, Esther Vázquez, Neus Ferrer-Miralles, Antonio Villaverde, Eloi Parladé

    Published 2023
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