Antisense RNA Design, Delivery, and Analysis

Table of Contents: “…Introduction and History of the Chemistry of Nucleic Acids Therapeutics -- Antisense RNA Therapeutics: A Brief Overview -- Design of Bifunctional Antisense Oligonucleotides for Exon Inclusion -- Design and Delivery of SINEUP: A New Modular Tool to Increase Protein Translation -- How to Design U1 snRNA Molecules for Splicing Rescue -- Conjugation of Nucleic Acids and Drugs to Gold Nanoparticles -- Determination of Optimum Ratio of Cationic Polymers and Small Interfering RNA with Agarose Gel Retardation Assay -- Generation of Protein-Phosphorodiamidate Morpholino Oligomer Conjugates for Efficient Cellular Delivery via Anthrax Protective Antigen -- Development and Use of Cellular Systems to Assess and Correct Splicing Defects -- Modeling Splicing Variants Amenable to Antisense Therapy by Use of CRISPR-Cas9-Based Gene Editing in HepG2 Cells -- In Vitro Models for the Evaluation of Antisense Oligonucleotides in Skin -- In Vitro Delivery of PMOs in Myoblasts by Electroporation -- Rapid Determination of MBNL1 Protein Levels by Quantitative Dot Blot for Evaluation of Antisense Oligonucleotides in Myotonic Dystrophy Myoblasts -- Evaluation of Exon Skipping and Dystrophin Restoration in In Vitro Models of Duchenne Muscular Dystrophy -- Generation of Human iPSC-Derived Myotubes to Investigate RNA-Based Therapies In Vitro -- Eye on a Dish Models to Evaluate Splicing Modulation -- Establishment of In Vitro Brain Models for AON Delivery -- Considerations for Generating Humanized Mouse Models to Test Efficacy of Antisense Oligonucleotides -- Generation of Humanized Zebrafish Models for the In Vivo Assessment of Antisense Oligonucleotide-Based Splice Modulation Therapies -- Use of Small Animal Models for Duchenne and Parameters to Assess Efficiency upon Antisense Treatment -- In Vivo Models for the Evaluation of Antisense Oligonucleotides in Skin -- Delivery of Antisense Oligonucleotides to the Mouse Retina -- Delivery of Antisense Oligonucleotides to the Mouse Brain by Intracerebroventricular Injections -- Intrathecal Delivery of Therapeutic Oligonucleotides for Potent Modulation of Gene Expression in the Central Nervous System -- Preclinical Safety Assessment of Therapeutic Oligonucleotides -- Preclinical Evaluation of the Renal Toxicity of Oligonucleotide Therapeutics in Mice -- Protocol for Isolation and Culture of Mouse Hepatocytes (HCs), Kupffer Cells (KCs), and Liver Sinusoidal Endothelial Cells (LSECs) in Analyses of Hepatic Drug Distribution -- Patent Considerations When Embarking on New Antisense Drug Programs.…”
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Biotechnologie praxisorientiert unterrichten Aktuelle Kontexte für Schule und Lehrerfortbildung / by Schöppner, Patricia, Großbruchhaus, Sara, Nerdel, Claudia

Table of Contents: “…Einleitung -- Fachwissenschaftlicher Hintergrund: Von der DNA zum Protein -- Methodische Grundlagen: Von der Entdeckung zur Nutzung der DNA -- Fachdidaktischer Hintergrund: Gestaltung eines innovativen Biologieunterrichts -- Praktische Umsetzung an der Schule -- Tatort DNA -- Eat, Sleep, Repeat - Wie Evolution unsere innere Uhr beeinflusst -- Taste Impossible - Wie die Zunge uns schützt -- Food Wars Episode I: Laktoseintoleranz schlägt zurück -- Food Wars Episode II - Eine neue Hoffnung: Herstellung laktosefreier Milchprodukte -- Eine runde Sache: W-Seminar Angebote an bayerischen Gymnasien.…”
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The Basics of General, Organic, and Biological Chemistry by Ball, David W, Hill, John W, Scott, Rhonda J

Table of Contents: “…Chapter 1: Chemistry, Matter, and Measurement -- Chapter 2: Elements, Atoms, and the Periodic Table -- Chapter 3: Ionic Bonding and Simple Ionic Compounds -- Chapter 4: Covalent Bonding and Simple Molecular Compounds -- Chapter 5: Introduction to Chemical Reactions -- Chapter 6: Quantities in Chemical Reactions -- Chapter 7: Energy and Chemical Processes -- Chapter 8: Solids, Liquids, and Gases -- Chapter 9: Solutions -- Chapter 10: Acids and Bases -- Chapter 11: Nuclear Chemistry -- Chapter 12: Organic Chemistry: Alkanes and Halogenated Hydrocarbons -- Chapter 13: Unsaturated and Aromatic Hydrocarbons -- Chapter 14: Organic Compounds of Oxygen -- Chapter 15: Organic Acids and Bases and Some of Their Derivatives -- Chapter 16: Carbohydrates -- Chapter 17: Lipids -- Chapter 18: Amino Acids, Proteins, and Enzymes -- Chapter 19: Nucleic Acids -- Chapter 20: Energy Metabolism…”
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From Growing to Biology Plants 1e by Hacisalihoglu, Gokhan

Table of Contents: “…HUMAN NUTRITION FROM PLANTS AND PLANT-BASED PROTEINS -- CHAPTER 20. SEED GERMINATION AND SEEDLING ESTABLISHMMENT -- CHAPTER 21. …”
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A dynamic interplay between membranes and the cytoskeleton critical for cell development and signaling by Clement Thomas

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Frontiers of Sulfur Metabolism in Plant Growth, Development, and Stress Response by Stanislav Kopriva

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Myelin-Mediated Inhibition of Axonal Regeneration: Past, Present, and Future by Wilfredo Mellado

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Neural circuits underlying emotion and motivation: Insights from optogenetics and pharmacogenetics by Mary Kay Lobo

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The Proceedings from Halophiles 2013, the International Congress on Halophilic Microorganisms by Antonio Ventosa

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Single Membrane Channels Formed by Connexins or Pannexins: Focus on the Nervous System by Juan Andres Orellana

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Systems Biology of Transcription Regulation by Joerg Linde

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Dietary Plant Origin Bio-Active Compounds, Intestinal Functionality and Microbiome

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Electrical Properties of Model Lipid Membranes

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Applications of Instrumental Methods for Food and Food By-Products Analysis

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Review on the epidemiology of Bovine Rotavirus and its public health significance by Abebe Garoma Gichile

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Pemanfaatan Ampas Tahu Dan Daun Kelor Sebagai Media Tambahan Untuk Pertumbuhan Dan Produktivitas Jamur Tiram Putih (Pleurotus ostreatus) by Rahmawati, Jevi Milda, , Dra. Suparti, M.Si

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Pertumbuhan Misellium Bibit F1 Jamur Tiram(Pleurotus Ostreatus) Dan Jamur Merang (Volvariella Volvaceae) PadaMedia Kacang Hijau Dan Kedelai Hitam Dari Bibit F0Media Biji Nangka by Ekawati, Desy, , Dra. Suparti, M.Si

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POTENSI DELIMA (PUNICA GRANATUM) SEBAGAI HEPATOPROTEKTOR TERHADAP PERBAIKAN HISTOPATOLOGI HEPAR PADA KEADAAN HEPATOTOKSISITAS IMBAS OBAT SECARA IN VIVO : SYSTEMATIC LITERATURE REVI... by Marwah Widhawati,

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OPTIMASI FERMENTASI ISOLAT ACTINOMYCETES SEBAGAI ANTIBAKTERI TERHADAP PERTUMBUHAN STAPHYLOCOCCUS AUREUS SECARA IN VITRO by Anastasia Joanne,

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Principles of Biology Biology 211, 212, and 213 by Bartee, Lisa, Shriner, Walter, Creech, Catherine

Table of Contents: “…-- Cell Structure and Function -- The Cell Membrane and Transport -- Cell Communication -- Enzyme-catalyzed reactions -- How cells obtain energy -- Photosynthesis -- Cell Division - Binary Fission and Mitosis -- BIOLOGY 212 - Genetics -- DNA and Chromosome Structure -- DNA Replication -- Mutations -- Protein Synthesis -- Gene Regulation -- Meiosis - Sexual Reproduction -- Patterns of Inheritance -- Genetics: Dog Coat Color -- Biotechnology -- BIOLOGY 213 - Ecology and Evolution -- Introduction to Evolution -- Evolution in Action -- Evolutionary Relationships -- Ecology and the Biosphere -- Population and Community Ecology -- Ecosystems -- Conservation Biology and Biodiversity…”
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