Arama Sonuçları - "pyrimidine"

Recombinant Photolyase-Thymine Alleviated UVB-Induced Photodamage in Mice by Repairing CPD Photoproducts and Ameliorating Oxidative Stress Yazar: Zhaoyang Wang, Ziyi Li, Yaling Lei, Yuan Liu, Yuqing Feng, Derong Chen, Siying Ma, Ziyan Xiao, Meirong Hu, Jingxian Deng, Yuxin Wang, Qihao Zhang, Yadong Huang, Yan Yang

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Adipocyte Xbp1s overexpression drives uridine production and reduces obesity Yazar: Yingfeng Deng, Zhao V. Wang, Ruth Gordillo, Yi Zhu, Aktar Ali, Chen Zhang, Xiaoding Wang, Mengle Shao, Zhuzhen Zhang, Puneeth Iyengar, Rana K. Gupta, Jay D. Horton, Joseph A. Hill, Philipp E. Scherer

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Inhibition studies on a panel of human carbonic anhydrases with N1-substituted secondary sulfonamides incorporating thiazolinone or imidazolone-indole tails Yazar: Fadi M. Awadallah, Silvia Bua, Walaa R. Mahmoud, Hossam H. Nada, Alessio Nocentini, Claudiu T. Supuran

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A computational multi-targeting approach for drug repositioning for psoriasis treatment Yazar: Akachukwu Ibezim, Emmanuel Onah, Ebubechukwu N. Dim, Fidele Ntie-Kang

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Biological Evaluations and Computer-Aided Approaches of Janus Kinases 2 and 3 Inhibitors for Cancer Treatment: A Review Yazar: Lenci K. Vázquez-Jiménez, Gildardo Rivera, Alfredo Juárez-Saldivar, Jessica L. Ortega-Balleza, Eyra Ortiz-Pérez, Elena Jaime-Sánchez, Alma Paz-González, Edgar E. Lara-Ramírez

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Quetiapine and novel PDE10A inhibitors potentiate the anti-BuChE activity of donepezil Yazar: Joanna Sikora, Maria Podsiedlik, Tadeusz Pietras, Marcin Kosmalski, Mikołaj Matłoka, Rafał Moszczyński-Petkowski, Maciej Wieczorek, Magdalena Markowicz-Piasecka

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Guanine Deaminase Stimulates Ultraviolet-induced Keratinocyte Senescence in Seborrhoeic Keratosis via Guanine Metabolites Yazar: Kyung Ah Cheong, Ai-Young Lee

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Anticancer properties and mechanism of action of the fungal nucleoside clitocine and its derivatives Yazar: Christian Bailly

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Synergistic Killing of Polymyxin B in Combination With the Antineoplastic Drug Mitotane Against Polymyxin-Susceptible and -Resistant Acinetobacter baumannii: A Metabolomic Study Yazar: Thien B. Tran, Thien B. Tran, Phillip J. Bergen, Darren J. Creek, Tony Velkov, Tony Velkov, Jian Li

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Formyl-Peptide Receptor 2 Signaling Redirects Glucose and Glutamine into Anabolic Pathways in Metabolic Reprogramming of Lung Cancer Cells Yazar: Tiziana Pecchillo Cimmino, Ester Pagano, Mariano Stornaiuolo, Gabriella Esposito, Rosario Ammendola, Fabio Cattaneo

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Metabolic Characterization of Antifolate Responsiveness and Non-responsiveness in Malignant Pleural Mesothelioma Cells Yazar: Yuzo Sato, Yuzo Sato, Yuzo Sato, Yuzo Sato, Shiori Matsuda, Shiori Matsuda, Shiori Matsuda, Ami Maruyama, Ami Maruyama, Joji Nakayama, Joji Nakayama, Joji Nakayama, Tomoyuki Miyashita, Tomoyuki Miyashita, Tomoyuki Miyashita, Hibiki Udagawa, Shigeki Umemura, Kazuyoshi Yanagihara, Atsushi Ochiai, Masaru Tomita, Masaru Tomita, Tomoyoshi Soga, Tomoyoshi Soga, Katsuya Tsuchihara, Hideki Makinoshima, Hideki Makinoshima

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Molecular design, synthesis and in vitro biological evaluation of thienopyrimidine-hydroxamic acids as chimeric kinase HDAC inhibitors: a challenging approach to combat cancer Yazar: Mona M. Abdel-Atty, Nahla A. Farag, Rabah A. T. Serya, Khaled A. M. Abouzid, Samar Mowafy

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Design, synthesis, and biological investigation of selective human carbonic anhydrase II, IX, and XII inhibitors using 7-aryl/heteroaryl triazolopyrimidines bearing a sulfanilamide... Yazar: Romeo Romagnoli, Tiziano De Ventura, Stefano Manfredini, Erika Baldini, Claudiu T. Supuran, Alessio Nocentini, Andrea Brancale, Carmine Varricchio, Roberta Bortolozzi, Lorenzo Manfreda, Giampietro Viola

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Design, Synthesis and Biological Investigation of 2-Anilino Triazolopyrimidines as Tubulin Polymerization Inhibitors with Anticancer Activities Yazar: Romeo Romagnoli, Paola Oliva, Filippo Prencipe, Stefano Manfredini, Federica Budassi, Andrea Brancale, Salvatore Ferla, Ernest Hamel, Diana Corallo, Sanja Aveic, Lorenzo Manfreda, Elena Mariotto, Roberta Bortolozzi, Giampietro Viola

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Profiling Ribonucleotide and Deoxyribonucleotide Pools Perturbed by Remdesivir in Human Bronchial Epithelial Cells Yazar: Yan Li, Hui-Xia Zhang, Wen-Di Luo, Christopher Wai Kei Lam, Cai-Yun Wang, Li-Ping Bai, Vincent Kam Wai Wong, Wei Zhang, Zhi-Hong Jiang

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Transcriptomics and metabolomics reveal changes in the regulatory mechanisms of osteosarcoma under different culture methods in vitro Yazar: Sen Yang, Zhi Tian, Yi Feng, Kun Zhang, Yongchun Pan, Yuan Li, Zhichao Wang, Wenhao Wei, Xiaochen Qiao, Ruhao Zhou, Lei Yan, Qian Li, Hua Guo, Jie Yuan, Pengcui Li, Zhi Lv

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Design, Synthesis, In Vitro, and In Silico Studies of New <i>N</i>⁵-Substituted-pyrazolo[3,4-<i>d</i>]pyrimidinone Derivatives as Anticancer CDK2 Inhibitors Yazar: Waheed A. Zaki, Selwan M. El-Sayed, Mohamed Alswah, Ahmed El-Morsy, Ashraf H. Bayoumi, Abrahman S. Mayhoub, Walaa H. Moustafa, Aeshah A. Awaji, Eun Joo Roh, Ahmed H.E. Hassan, Kazem Mahmoud

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Shenfu injection improves isoproterenol-induced heart failure in rats by modulating co-metabolism and regulating the trimethylamine-N-oxide - inflammation axis Yazar: Lin Li, Lin Li, Jiahao Ye, Zhenyu Zhao, Siyuan Hu, Hao Liang, Hao Liang, Ji Ouyang, Zhixi Hu, Zhixi Hu

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MOLECULAR MECHANISMS OF ACTION OF MAGNESIUM OROTATE ON CARDIOVASCULAR SYSTEM Yazar: I. Yu. Torshin, O. A. Gromova

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Novel Purine Chemotypes with Activity against <i>Plasmodium falciparum</i> and <i>Trypanosoma cruzi</i> Yazar: Nieves Martinez-Peinado, Álvaro Lorente-Macías, Alejandro García-Salguero, Nuria Cortes-Serra, Ángel Fenollar-Collado, Albert Ros-Lucas, Joaquim Gascon, Maria-Jesus Pinazo, Ignacio J. Molina, Asier Unciti-Broceta, Juan J. Díaz-Mochón, María J. Pineda de las Infantas y Villatoro, Luis Izquierdo, Julio Alonso-Padilla

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